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The primary data page shows the detailed antibody staining in 76 different cell types for each analyzed antibody. In addition, for each cell type, a knowledge-based annotated protein expression score based on all analyzed antibodies is displayed furthest to the right. The images and annotations can be accessed by clicking on the tissue name or score bar. More information can be found in Assays & Annotation.
The tissues and cell types can be ordered by organ, cell type or alphabetically. If ordered by organ, the tissues are presented in groups according to functional features. If ordered by cell type, the cells are presented in groups related to origin.
This score describes the level of antibody staining observed in the annotated cell types as not detected (n), low (l), medium (m) or high (h). It is based on the staining intensity and fraction of stained cells. The images and annotations can be accessed by clicking on the tissue name or score bar. More information can be found in Assays & Annotation.
Annotated protein expressioni
This score describes a knowledge-based best estimate of the protein expression in the annotated cell types as not detected (n), low (l), medium (m) or high (h). It is a result of stringent evaluation of immunohistochemical staining pattern, RNA data from internal and external sources and available protein/gene characterization data. More information can be found in Assays & Annotation.
Summarizing texts describe the staining pattern for each antibody based on staining intensity, fraction of stained cells and subcellular localization. More information can be found in Assays & Annotation.
HPA019135
Subsets of lymphoid and inflammatory cells as well as glial and hematopoietic cells displayed moderate to strong cytoplasmic positivity. Renal tubules showed moderate membranous staining. Remaining normal tissues were weakly stained or negative.
HPA019137
Subtypes of immune cells, mainly located outside the germinal centra, displayed moderate to strong nuclear positivity. Strong nuclear staining was also observed in a few cells in respiratory epithelium. Remaining normal tissues were negative.
HPA027198
Adrenal glandular cells displayed strong cytoplasmic positivity while moderate staining was observed in the large intestine, hepatocytes, renal tubuli, placental trophoblasts and subsets of neuronal cells. Lymphoid cells in non-germinal center and renal glomeruli showed distinct nuclear positivity.
The Human Protein Atlas project is funded
