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The primary data page shows the detailed antibody staining in 76 different cell types for each analyzed antibody. In addition, for each cell type, a knowledge-based annotated protein expression score based on all analyzed antibodies is displayed furthest to the right. The images and annotations can be accessed by clicking on the tissue name or score bar. More information can be found in Assays & Annotation.
The tissues and cell types can be ordered by organ, cell type or alphabetically. If ordered by organ, the tissues are presented in groups according to functional features. If ordered by cell type, the cells are presented in groups related to origin.
This score describes the level of antibody staining observed in the annotated cell types as not detected (n), low (l), medium (m) or high (h). It is based on the staining intensity and fraction of stained cells. The images and annotations can be accessed by clicking on the tissue name or score bar. More information can be found in Assays & Annotation.
Annotated protein expressioni
This score describes a knowledge-based best estimate of the protein expression in the annotated cell types as not detected (n), low (l), medium (m) or high (h). It is a result of stringent evaluation of immunohistochemical staining pattern, RNA data from internal and external sources and available protein/gene characterization data. More information can be found in Assays & Annotation.
Summarizing texts describe the staining pattern for each antibody based on staining intensity, fraction of stained cells and subcellular localization. More information can be found in Assays & Annotation.
HPA023420
Most normal tissues showed moderate cytoplasmic positivity. Bile duct cells, gall bladder, renal tubules and neuronal cells of the hippocampus displayed strong staining. Pancreatic islet cells and renal glomeruli were negative.
HPA023422
Most of the normal cells showed moderate cytoplasmic positivity. Strong staining was observed in hepatocytes, exocrine pancreas, renal tubuli, placenta and a subset of lymphoid cells outside the reaction centra of lymphoid tissues. Skin, glial cells and reaction center cells of lymphoid tissues were either negative or weakly stained.
CAB013497
Normal tissues showed moderate cytoplasmic staining. Squamous epithelia, gastrointestinal glands, pancreatic acini, trophoblastic cells and hematopoietic cells displayed strong staining. Kidney, liver, myocytes and glial cells were weakly stained or negative.
The Human Protein Atlas project is funded
