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The primary data page shows the detailed antibody staining in 76 different cell types for each analyzed antibody. In addition, for each cell type, a knowledge-based annotated protein expression score based on all analyzed antibodies is displayed furthest to the right. The images and annotations can be accessed by clicking on the tissue name or score bar. More information can be found in Assays & Annotation.
The tissues and cell types can be ordered by organ, cell type or alphabetically. If ordered by organ, the tissues are presented in groups according to functional features. If ordered by cell type, the cells are presented in groups related to origin.
This score describes the level of antibody staining observed in the annotated cell types as not detected (n), low (l), medium (m) or high (h). It is based on the staining intensity and fraction of stained cells. The images and annotations can be accessed by clicking on the tissue name or score bar. More information can be found in Assays & Annotation.
Annotated protein expressioni
This score describes a knowledge-based best estimate of the protein expression in the annotated cell types as not detected (n), low (l), medium (m) or high (h). It is a result of stringent evaluation of immunohistochemical staining pattern, RNA data from internal and external sources and available protein/gene characterization data. More information can be found in Assays & Annotation.
Summarizing texts describe the staining pattern for each antibody based on staining intensity, fraction of stained cells and subcellular localization. More information can be found in Assays & Annotation.
HPA052217
Most normal tissues displayed weak to moderate cytoplasmic and/or nuclear positivity. Exocrine glandular cells and follicle cells showed strong positivity. Liver and cells in CNS were weakly stained or negative.
HPA057284
Weak to moderate cytoplasmic positivity was observed in most normal tissues. Islets of Langerhans and adrenal gland were strongly stained. Squamous epithelial cells, uterus, cervix, breast, prostate, cells of CNS, hematopoietic cells and soft tissues were negative.
CAB004978
Most normal tissues displayed moderate nuclear and cytoplasmic positivity. Additional membranous staining was observed in intestinal glands, fallopian tube and gallbladder. Small intestine, Leydig cells and neuronal cells of cerebral cortex were strongly stained.
The Human Protein Atlas project is funded
