We use cookies to enhance the usability of our website. If you continue, we'll assume that you are happy to receive all cookies. More information. Don't show this again.
The Survival Scatter plot shows the clinical status (i.e. dead or alive) for all individuals in the patient cohort, based on the same data that underlies the corresponding Kaplan-Meier plots. Patients that are alive at last time for follow-up are shown in blue and patients who have died during the study are shown in red.
The x-axis shows the expression levels (FPKM) of the investigated gene in the tumor tissue at the time of diagnosis. The y-axis shows the follow-up time after diagnosis (years). Both axes are complimented with kernel density curves demonstrating the data density over the axes. The top density plot shows the expression levels (FPKM) distribution among dead (red) and alive patients (blue). The right density plot shows the data density of the survived years of dead patients with high and low expression levels respectively, stratified using the cutoff indicated by the vertical dashed line through the Survival Scatter plot. This cutoff is automatically defined based on the FPKM cutoff that minimizes the p-score. The cutoff can be changed by dragging the vertical line or by entering a cutoff value in the square labeled "Current cut-off".
Under the Survival Scatter plot the p-score landscape (black curve; left axis) is shown together with dead median separation (red curve; right axis). Dead median separation is the difference in median mRNA expression between patients who have died with high and low expression, respectively. It is calculated as follows: median FPKM expression of dead patients with high expression - median FPKM expression of dead patients with low expression. This is intended to aid the user in visually exploring custom cutoffs and the associated p-scores and dead median separation.
Individual patient data is displayed and can be filtered by clicking on one or more of the category buttons on the top of the page. Categories describing expression level and patient information include: high, low, alive, dead, female, male and tumor stages. The scale of the x-axis can be toggled between linear and log-scale by clicking on the "x log" button. Mouse-over function shows TCGA ID, patient information and mRNA expression (FPKM) for each patient.
& Survival analysisi
Kaplan-Meier plots summarize results from analysis of correlation between mRNA expression level and patient survival. Patients were divided based on level of expression into one of the two groups "low" (under cut off) or "high" (over cut off). X-axis shows time for survival (years) and y-axis shows the probability of survival, where 1.0 corresponds to 100 percent.
RPL36 is not prognostic in Pancreatic Adenocarcinoma (TCGA)
Stage:
Survival analysis
Current cut offi
Current cut-off shows the cut-off (FPKM) currently selected. It may be changed manually. When the current cut-off is changed, the vertical dashed line indicating cut-off, the interactive survival scatter plot and the Kaplan-Meier curve will be automatically adjusted to show results accordingly.
:
Best expression cut offi
Based on the FPKM value of each gene, patients were classified into two groups and association between prognosis (survival) and gene expression (FPKM) was examined. The best expression cut-off refers the FPKM value that yields maximal difference with regard to survival between the two groups at the lowest log-rank P-value. Best expression cut-off was selected based on survival analysis .
When clicking on this number, the vertical dashed line indicating cut-off, the interactive survival plot, and the Kaplan-Meier curve will be adjusted to show results based on the best expression cut-off.
Median expression refers to the median FPKM value calculated based on the gene expression (FPKM) data from all patients in this dataset. When clicking on this number, the vertical dashed line indicating cut-off, the interactive survival plot, and the Kaplan-Meier curve will be adjusted to show results based on the median expression.
Median follow up time refers to the median time (years) after diagnosis with this type of cancer, based on clinical data from all patients in this dataset.
: N/A
P scorei
Log-rank P value for Kaplan-Meier plot showing results from analysis of correlation between mRNA expression level and patient survival.
N/A
5-year survival highi
5-year survival for patients with higher expression than the expression cutoff.
For melanoma and glioma, 3-year survival is shown.
N/A
5-year survival lowi
5-year survival for patients with lower expression than the expression cutoff.
For melanoma and glioma, 3-year survival is shown.
N/A
TCGA RNA samplesi
RNA-seq data is reported as average FPKM (number Fragments Per Kilobase of exon per Million reads), generated by the The Cancer Genome Atlas (TCGA) .
Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. FPKM values of the individual samples are presented next to the box plot.
Average TPM
1367.3
Number of samples
176
Samples
Sample
Description
TPM
TCGA-HV-A7OP-01A
0 years, male, asian, stage:Stage IIB, alive, 978 days
8654.5
TCGA-IB-A7M4-01A
0 years, male, white, stage:Stage IIB, alive, 483 days
2757.0
TCGA-FB-AAQ0-01A
0 years, male, white, stage:Stage IIA, dead, 473 days
2369.4
TCGA-HZ-A9TJ-01A
0 years, male, white, stage:Stage IV, alive, 603 days
2361.1
TCGA-FB-A5VM-01A
0 years, male, white, stage:Stage IB, dead, 498 days
2348.0
TCGA-FB-AAQ6-01A
0 years, male, white, stage:Stage IA, dead, 244 days
2325.7
TCGA-FB-AAQ2-01A
0 years, female, white, stage:Stage IIB, dead, 153 days
2308.6
TCGA-HV-A7OL-01A
0 years, male, asian, stage:Stage IIA, alive, 252 days
2307.3
TCGA-FB-AAQ3-01A
0 years, female, white, stage:Stage IIB, dead, 31 days
2251.1
TCGA-IB-7886-01A
0 years, male, white, stage:Stage IIB, dead, 123 days
2199.4
TCGA-OE-A75W-01A
0 years, male, white, stage:Stage IIA, dead, 267 days
2176.0
TCGA-S4-A8RO-01A
0 years, female, white, stage:Stage IIB, alive, 525 days
2148.3
TCGA-2L-AAQE-01A
0 years, male, white, stage:Stage IIB, dead, 684 days
2137.5
TCGA-Z5-AAPL-01A
0 years, female, white, stage:Stage IIA, alive, 467 days
2128.3
TCGA-FB-AAPZ-01A
0 years, male, white, stage:Stage IIB, alive, 716 days
2096.0
TCGA-IB-AAUO-01A
0 years, female, white, stage:Stage IIB, dead, 239 days
2077.0
TCGA-YY-A8LH-01A
0 years, female, white, stage:Stage IIB, alive, 2016 days
2045.6
TCGA-F2-6879-01A
0 years, male, white, stage:Stage IIB, dead, 334 days
2041.2
TCGA-2J-AABI-01A
0 years, female, white, stage:Stage IIA, alive, 969 days
2028.0
TCGA-3A-A9I5-01A
0 years, male, white, stage:'--, alive, 1794 days
1971.0
TCGA-IB-7887-01A
0 years, female, white, stage:Stage IIB, dead, 110 days
1964.7
TCGA-2L-AAQL-01A
0 years, male, white, stage:Stage IIB, dead, 292 days
1957.9
TCGA-HZ-7289-01A
0 years, male, white, stage:Stage IIB, dead, 661 days
1910.5
TCGA-IB-7889-01A
0 years, female, white, stage:Stage IIB, dead, 481 days
1886.0
TCGA-LB-A8F3-01A
0 years, female, black or african american, stage:Stage IIA, alive, 379 days
1873.0
TCGA-US-A779-01A
0 years, female, white, stage:Stage IIB, dead, 511 days
1860.0
TCGA-3E-AAAZ-01A
0 years, male, white, stage:Stage IIA, dead, 2182 days
1841.5
TCGA-FB-A545-01A
0 years, female, white, stage:Stage IIB, dead, 732 days
1839.2
TCGA-2J-AABV-01A
0 years, male, white, stage:Stage IIB, dead, 652 days
1826.3
TCGA-2J-AABK-01A
0 years, male, white, stage:Stage IIB, alive, 484 days
1806.6
TCGA-IB-7644-01A
0 years, female, white, stage:Stage IV, dead, 394 days
1795.8
TCGA-2J-AAB8-01A
0 years, male, white, stage:Stage IIB, alive, 80 days
1794.8
TCGA-2J-AAB6-01A
0 years, male, white, stage:Stage IIA, dead, 293 days
1792.8
TCGA-3A-A9IL-01A
0 years, female, white, stage:Stage I, alive, 2741 days
1775.4
TCGA-Q3-A5QY-01A
0 years, male, white, stage:Stage IIB, alive, 416 days
1750.2
TCGA-FB-AAPQ-01A
0 years, male, white, stage:Stage IIB, dead, 1130 days
1743.0
TCGA-IB-A5SP-01A
0 years, male, white, stage:Stage IIA, alive, 482 days
1729.8
TCGA-RL-AAAS-01A
0 years, female, white, stage:Stage IB, alive, 9 days
1727.7
TCGA-FB-A78T-01A
0 years, female, white, stage:Stage IIB, dead, 375 days
1725.0
TCGA-3A-A9IN-01A
0 years, female, white, stage:Stage IB, alive, 2084 days
1719.5
TCGA-2J-AAB1-01A
0 years, male, white, stage:Stage IIB, dead, 66 days
1692.2
TCGA-US-A77J-01A
0 years, female, white, stage:Stage IIB, dead, 568 days
1689.3
TCGA-IB-AAUR-01A
0 years, male, white, stage:Stage IIB, alive, 338 days
1680.6
TCGA-HZ-8001-01A
0 years, male, white, stage:Stage III, alive, 706 days
1632.1
TCGA-Q3-AA2A-01A
0 years, female, white, stage:Stage IB, alive, 95 days
1613.8
TCGA-3A-A9IB-01A
0 years, female, white, stage:Stage IIB, dead, 224 days
1590.6
TCGA-IB-A7LX-01A
0 years, male, white, stage:Stage IIB, dead, 250 days
1589.9
TCGA-HZ-A8P1-01A
0 years, male, white, stage:Stage IB, alive, 7 days
1581.6
TCGA-S4-A8RM-01A
0 years, male, white, stage:Stage IIB, alive, 737 days
1580.1
TCGA-2L-AAQA-01A
0 years, male, white, stage:Stage IIB, dead, 143 days
1547.5
TCGA-F2-A44G-01A
0 years, female, white, stage:Stage IIB, dead, 233 days
1493.8
TCGA-FB-AAPU-01A
0 years, female, asian, stage:Stage IIA, dead, 381 days
1479.0
TCGA-YH-A8SY-01A
0 years, female, white, stage:'--, alive, 388 days
1470.7
TCGA-PZ-A5RE-01A
0 years, female, white, stage:Stage IIB, dead, 470 days
1457.8
TCGA-XD-AAUI-01A
0 years, female, white, stage:Stage IIB, dead, 366 days
1447.8
TCGA-3A-A9IJ-01A
0 years, male, white, stage:Stage IB, alive, 1854 days
1440.9
TCGA-HZ-8005-01A
0 years, male, white, stage:Stage IIB, dead, 120 days
1440.5
TCGA-YB-A89D-01A
0 years, male, white, stage:Stage IIB, alive, 350 days
1438.6
TCGA-IB-AAUV-01A
0 years, male, white, stage:Stage IIB, alive, 404 days
1421.4
TCGA-XN-A8T5-01A
0 years, female, white, stage:Stage IB, alive, 720 days
1420.3
TCGA-3A-A9IV-01A
0 years, female, white, stage:Stage IB, alive, 1103 days
1415.2
TCGA-XD-AAUG-01A
0 years, female, white, stage:Stage IV, alive, 420 days
1407.0
TCGA-HZ-A49H-01A
0 years, female, white, stage:Stage IIB, alive, 491 days
1397.5
TCGA-IB-A6UG-01A
0 years, male, white, stage:Stage IIB, dead, 41 days
1390.0
TCGA-2J-AABA-01A
0 years, male, white, stage:Stage IIB, dead, 607 days
1389.7
TCGA-FB-AAQ1-01A
0 years, male, white, stage:Stage IIB, dead, 123 days
1370.7
TCGA-IB-AAUS-01A
0 years, female, white, stage:Stage IIB, alive, 225 days
1360.3
TCGA-2J-AABH-01A
0 years, male, white, stage:Stage IIA, alive, 1287 days
1357.8
TCGA-2J-AAB9-01A
0 years, female, white, stage:Stage IIB, dead, 627 days
1356.7
TCGA-3E-AAAY-01A
0 years, male, white, stage:Stage IIB, alive, 2285 days
1354.2
TCGA-HV-A5A4-01A
0 years, female, asian, stage:Stage IIA, alive, 232 days
1331.8
TCGA-3A-A9IR-01A
0 years, female, white, stage:Stage IB, alive, 1542 days
1331.2
TCGA-3A-A9J0-01A
0 years, male, white, stage:Stage IIB, alive, 743 days
1317.2
TCGA-3A-A9IX-01A
0 years, male, white, stage:Stage IA, alive, 1037 days
1316.5
TCGA-H8-A6C1-01A
0 years, male, white, stage:Stage IIA, alive, 671 days
1307.3
TCGA-XD-AAUH-01A
0 years, female, white, stage:Stage IIB, alive, 395 days
1307.0
TCGA-IB-7888-01A
0 years, female, black or african american, stage:Stage IIA, dead, 1332 days
1293.8
TCGA-FB-AAPY-01A
0 years, male, white, stage:Stage IIB, dead, 1059 days
1279.0
TCGA-HV-A5A3-01A
0 years, male, asian, stage:Stage IIA, dead, 128 days
1277.7
TCGA-2J-AABE-01A
0 years, male, white, stage:Stage IIA, alive, 676 days
1273.1
TCGA-FB-A7DR-01A
0 years, male, asian, stage:Stage IIA, dead, 353 days
1257.4
TCGA-IB-A5SO-01A
0 years, male, white, stage:Stage IIB, dead, 365 days
1254.5
TCGA-HZ-7925-01A
0 years, male, white, stage:Stage IIB, dead, 614 days
1247.4
TCGA-2J-AAB4-01A
0 years, male, white, stage:Stage IIB, alive, 729 days
1245.9
TCGA-FB-AAPP-01A
0 years, male, white, stage:Stage IIB, dead, 485 days
1244.8
TCGA-2J-AABR-01A
0 years, female, white, stage:Stage IIA, alive, 438 days
1243.1
TCGA-FB-A4P5-01A
0 years, female, white, stage:Stage IIB, dead, 179 days
1235.3
TCGA-2L-AAQM-01A
0 years, male, white, stage:Stage IIB, alive, 1383 days
1232.3
TCGA-RB-A7B8-01A
0 years, female, white, stage:Stage IIB, dead, 466 days
1228.4
TCGA-2J-AABO-01A
0 years, male, white, stage:Stage IIB, alive, 440 days
1221.6
TCGA-IB-A6UF-01A
0 years, male, white, stage:Stage IIB, alive, 666 days
1210.4
TCGA-FB-AAPS-01A
0 years, female, white, stage:Stage IIB, alive, 228 days
1204.9
TCGA-HZ-A49I-01A
0 years, male, white, stage:Stage IIB, dead, 308 days
1203.0
TCGA-IB-AAUP-01A
0 years, male, white, stage:Stage IIB, alive, 431 days
1202.3
TCGA-US-A77G-01A
0 years, male, white, stage:Stage IIB, dead, 12 days
1197.9
TCGA-IB-A5SQ-01A
0 years, female, white, stage:Stage IB, dead, 219 days
1196.4
TCGA-3A-A9IH-01A
0 years, female, white, stage:Stage IA, alive, 1021 days
1193.9
TCGA-IB-A5ST-01A
0 years, female, white, stage:Stage IIB, alive, 635 days
1188.6
TCGA-IB-AAUQ-01A
0 years, male, white, stage:Stage IIB, dead, 183 days
1187.1
TCGA-HZ-A4BK-01A
0 years, male, white, stage:Stage IIB, alive, 657 days
1184.9
TCGA-3A-A9IC-01A
0 years, female, white, stage:Stage IIB, dead, 738 days
1182.8
TCGA-US-A776-01A
0 years, male, white, stage:Stage IIA, alive, 1216 days
1170.7
TCGA-IB-7893-01A
0 years, male, white, stage:Stage IIA, dead, 117 days
1163.1
TCGA-XD-AAUL-01A
0 years, male, white, stage:Stage IIA, alive, 498 days
1161.0
TCGA-3A-A9I7-01A
0 years, male, black or african american, stage:Stage IIB, alive, 1323 days
1153.5
TCGA-HV-AA8V-01A
0 years, male, asian, stage:Stage IIB, alive, 920 days
1123.7
TCGA-2L-AAQJ-01A
0 years, female, white, stage:Stage III, dead, 394 days
1119.8
TCGA-IB-AAUT-01A
0 years, male, white, stage:Stage IIB, alive, 287 days
1102.7
TCGA-2J-AABU-01A
0 years, male, white, stage:Stage IIB, dead, 277 days
1099.1
TCGA-F2-A44H-01A
0 years, male, white, stage:Stage IIA, alive, 586 days
1095.7
TCGA-3A-A9IU-01A
0 years, male, white, stage:Stage IIB, dead, 458 days
1092.9
TCGA-HZ-A77Q-01A
0 years, female, white, stage:Stage IIB, alive, 33 days
1092.3
TCGA-S4-A8RP-01A
0 years, female, white, stage:Stage IIB, dead, 702 days
1085.9
TCGA-2J-AABT-01A
0 years, female, white, stage:Stage IIB, alive, 319 days
1085.4
TCGA-3A-A9IZ-01A
0 years, male, white, stage:Stage IIB, dead, 308 days
1074.9
TCGA-HZ-7920-01A
0 years, male, white, stage:Stage IB, dead, 236 days
1069.8
TCGA-HZ-7926-01A
0 years, male, black or african american, stage:Stage IIB, dead, 518 days
1068.2
TCGA-FB-A4P6-01A
0 years, male, white, stage:Stage IIB, alive, 767 days
1065.6
TCGA-US-A77E-01A
0 years, male, white, stage:Stage IIB, dead, 430 days
1064.7
TCGA-H6-8124-01A
0 years, female, white, stage:Stage IIB, alive, 392 days
1059.9
TCGA-HZ-8002-01A
0 years, male, white, stage:Stage IIB, dead, 366 days
1053.7
TCGA-IB-7654-01A
0 years, male, white, stage:Stage IIB, dead, 476 days
1045.5
TCGA-US-A774-01A
0 years, female, white, stage:Stage IIB, dead, 695 days
1044.9
TCGA-HZ-A77O-01A
0 years, female, white, stage:Stage IIB, dead, 160 days
1040.8
TCGA-IB-7649-01A
0 years, female, stage:Stage IIB, dead, 467 days
1040.4
TCGA-IB-8127-01A
0 years, male, white, stage:Stage IIB, alive, 522 days
1039.9
TCGA-H6-A45N-01A
0 years, female, white, stage:Stage IIB, dead, 397 days
1038.6
TCGA-HZ-A77P-01A
0 years, male, white, stage:Stage IIB, alive, 330 days
1031.4
TCGA-F2-A7TX-01A
0 years, male, white, stage:Stage IIB, dead, 95 days
1027.7
TCGA-2L-AAQI-01A
0 years, male, white, stage:Stage IIB, dead, 103 days
1027.3
TCGA-2J-AABP-01A
0 years, female, white, stage:Stage IIB, alive, 463 days
1021.9
TCGA-IB-7890-01A
0 years, male, stage:Stage IB, dead, 598 days
1014.1
TCGA-RB-AA9M-01A
0 years, male, white, stage:Stage IIB, alive, 286 days
1010.8
TCGA-HV-AA8X-01A
0 years, female, asian, stage:Stage IIB, dead, 532 days
1006.9
TCGA-HZ-7919-01A
0 years, female, white, stage:Stage IIB, dead, 593 days
1002.5
TCGA-M8-A5N4-01A
0 years, female, stage:Stage IIA, alive, 584 days
998.8
TCGA-IB-AAUW-01A
0 years, female, white, stage:Stage IIB, dead, 230 days
984.4
TCGA-F2-7273-01A
0 years, male, black or african american, stage:Stage IIB, dead, 592 days
981.8
TCGA-HZ-8519-01A
0 years, male, white, stage:Stage IA, alive, 454 days
974.7
TCGA-IB-7885-01A
0 years, female, white, stage:Stage IIB, alive, 1257 days
970.8
TCGA-3A-A9I9-01A
0 years, male, white, stage:Stage IIA, dead, 634 days
970.2
TCGA-2J-AABF-01A
0 years, male, white, stage:Stage IIB, dead, 691 days
965.2
TCGA-XN-A8T3-01A
0 years, male, white, stage:Stage IB, alive, 951 days
959.9
TCGA-HZ-A49G-01A
0 years, female, white, stage:Stage IIB, alive, 660 days
951.0
TCGA-HZ-7924-01A
0 years, female, white, stage:Stage IIA, alive, 840 days
945.9
TCGA-IB-A5SS-01A
0 years, female, white, stage:Stage IIB, dead, 460 days
942.5
TCGA-IB-AAUU-01A
0 years, male, white, stage:Stage IIB, alive, 245 days
942.3
TCGA-IB-7652-01A
0 years, female, asian, stage:Stage IIB, alive, 1116 days
936.6
TCGA-3A-A9IO-01A
0 years, male, white, stage:'--, alive, 1942 days
917.8
TCGA-F2-7276-01A
0 years, male, white, stage:Stage IIB, dead, 216 days
915.0
TCGA-HZ-A4BH-01A
0 years, male, white, stage:Stage IIB, alive, 194 days
894.4
TCGA-HZ-7923-01A
0 years, male, white, stage:Stage IIA, alive, 314 days
893.4
TCGA-IB-7891-01A
0 years, female, white, stage:Stage IIB, dead, 913 days
889.8
TCGA-HZ-7922-01A
0 years, female, white, stage:Stage IIB, alive, 4 days
885.0
TCGA-3A-A9IS-01A
0 years, male, white, stage:Stage IB, alive, 998 days
881.0
TCGA-IB-7645-01A
0 years, female, stage:Stage IIB, dead, 1502 days
867.7
TCGA-IB-AAUM-01A
0 years, male, white, stage:Stage IIB, alive, 8 days
854.2
TCGA-LB-A9Q5-01A
0 years, female, white, stage:Stage IIB, dead, 313 days
835.3
TCGA-F2-A8YN-01A
0 years, male, white, stage:Stage IIA, alive, 517 days
834.7
TCGA-F2-6880-01A
0 years, male, white, stage:Stage IIB, alive, 295 days
830.4
TCGA-HV-A5A5-01A
0 years, female, asian, stage:Stage IIB, alive, 289 days
826.8
TCGA-IB-AAUN-01A
0 years, female, white, stage:Stage IB, dead, 144 days
822.7
TCGA-IB-7651-01A
0 years, female, white, stage:Stage IIB, dead, 603 days
819.4
TCGA-IB-7897-01A
0 years, female, white, stage:Stage IIB, dead, 486 days
804.8
TCGA-HV-A5A6-01A
0 years, female, asian, stage:Stage IIB, dead, 2036 days
796.6
TCGA-L1-A7W4-01A
0 years, female, white, stage:Stage IIB, dead, 278 days
756.1
TCGA-HZ-8636-01A
0 years, female, white, stage:Stage IV, dead, 545 days
734.3
TCGA-HZ-8315-01A
0 years, female, white, stage:Stage IIA, dead, 299 days
690.2
TCGA-HZ-8638-01A
0 years, female, white, stage:Stage IA, dead, 151 days
676.6
TCGA-HZ-8637-01A
0 years, female, white, stage:Stage IIB, dead, 517 days
668.3
TCGA-LB-A7SX-01A
0 years, female, black or african american, stage:Stage IIB, dead, 393 days
659.2
TCGA-HZ-8317-01A
0 years, female, white, stage:Stage IIB, dead, 378 days
643.0
TCGA-IB-7646-01A
0 years, male, white, stage:Stage IIB, dead, 145 days
630.8
TCGA-IB-8126-01A
0 years, female, white, stage:Stage III, alive, 462 days
557.2
TCGA-HZ-7918-01A
0 years, male, white, stage:Stage IIB, alive, 969 days
542.1
TCGA-HZ-8003-01A
0 years, female, white, stage:Stage IIB, dead, 596 days
The Survival Scatter plot shows the clinical status (i.e. dead or alive) for all individuals in the patient cohort, based on the same data that underlies the corresponding Kaplan-Meier plots. Patients that are alive at last time for follow-up are shown in blue and patients who have died during the study are shown in red.
The x-axis shows the expression levels (FPKM) of the investigated gene in the tumor tissue at the time of diagnosis. The y-axis shows the follow-up time after diagnosis (years). Both axes are complimented with kernel density curves demonstrating the data density over the axes. The top density plot shows the expression levels (FPKM) distribution among dead (red) and alive patients (blue). The right density plot shows the data density of the survived years of dead patients with high and low expression levels respectively, stratified using the cutoff indicated by the vertical dashed line through the Survival Scatter plot. This cutoff is automatically defined based on the FPKM cutoff that minimizes the p-score. The cutoff can be changed by dragging the vertical line or by entering a cutoff value in the square labeled "Current cut-off".
Under the Survival Scatter plot the p-score landscape (black curve; left axis) is shown together with dead median separation (red curve; right axis). Dead median separation is the difference in median mRNA expression between patients who have died with high and low expression, respectively. It is calculated as follows: median FPKM expression of dead patients with high expression - median FPKM expression of dead patients with low expression. This is intended to aid the user in visually exploring custom cutoffs and the associated p-scores and dead median separation.
Individual patient data is displayed and can be filtered by clicking on one or more of the category buttons on the top of the page. Categories describing expression level and patient information include: high, low, alive, dead, female, male and tumor stages. The scale of the x-axis can be toggled between linear and log-scale by clicking on the "x log" button. Mouse-over function shows TCGA ID, patient information and mRNA expression (FPKM) for each patient.
& Survival analysisi
Kaplan-Meier plots summarize results from analysis of correlation between mRNA expression level and patient survival. Patients were divided based on level of expression into one of the two groups "low" (under cut off) or "high" (over cut off). X-axis shows time for survival (years) and y-axis shows the probability of survival, where 1.0 corresponds to 100 percent.
RPL36 is not prognostic in Pancreatic Adenocarcinoma (validation)
Stage:
Survival analysis
Current cut offi
Current cut-off shows the cut-off (FPKM) currently selected. It may be changed manually. When the current cut-off is changed, the vertical dashed line indicating cut-off, the interactive survival scatter plot and the Kaplan-Meier curve will be automatically adjusted to show results accordingly.
:
Best expression cut offi
Based on the FPKM value of each gene, patients were classified into two groups and association between prognosis (survival) and gene expression (FPKM) was examined. The best expression cut-off refers the FPKM value that yields maximal difference with regard to survival between the two groups at the lowest log-rank P-value. Best expression cut-off was selected based on survival analysis .
When clicking on this number, the vertical dashed line indicating cut-off, the interactive survival plot, and the Kaplan-Meier curve will be adjusted to show results based on the best expression cut-off.
Median expression refers to the median FPKM value calculated based on the gene expression (FPKM) data from all patients in this dataset. When clicking on this number, the vertical dashed line indicating cut-off, the interactive survival plot, and the Kaplan-Meier curve will be adjusted to show results based on the median expression.
Median follow up time refers to the median time (years) after diagnosis with this type of cancer, based on clinical data from all patients in this dataset.
: N/A
P scorei
Log-rank P value for Kaplan-Meier plot showing results from analysis of correlation between mRNA expression level and patient survival.
N/A
5-year survival highi
5-year survival for patients with higher expression than the expression cutoff.
For melanoma and glioma, 3-year survival is shown.
N/A
5-year survival lowi
5-year survival for patients with lower expression than the expression cutoff.
For melanoma and glioma, 3-year survival is shown.
N/A
TCGA RNA samplesi
RNA-seq data is reported as average FPKM (number Fragments Per Kilobase of exon per Million reads), generated by the The Cancer Genome Atlas (TCGA) .
Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. FPKM values of the individual samples are presented next to the box plot.
Average TPM
352.7
Number of samples
80
Samples
Sample
Description
TPM
DO34961
0 years, male, NA, stage:, dead, 632 days
1002.7
DO49079
0 years, male, NA, stage:, dead, 332 days
843.3
DO33400
0 years, female, NA, stage:, alive, 1043 days
769.2
DO49168
0 years, male, NA, stage:, alive, 149 days
731.6
DO34785
0 years, female, NA, stage:, alive, 721 days
690.9
DO49080
0 years, male, NA, stage:, alive, 83 days
660.5
DO33368
0 years, male, NA, stage:, dead, 98 days
560.7
DO34680
0 years, male, NA, stage:, dead, 99 days
553.5
DO34817
0 years, female, NA, stage:, alive, 540 days
544.6
DO34504
0 years, male, NA, stage:, dead, 257 days
533.4
DO49204
0 years, male, NA, stage:, dead, 156 days
529.8
DO34264
0 years, female, NA, stage:, dead, 1144 days
522.2
DO34616
0 years, female, NA, stage:, alive, 666 days
500.2
DO34905
0 years, male, NA, stage:, alive, 1142 days
499.7
DO49193
0 years, male, NA, stage:, dead, 1 days
485.7
DO49164
0 years, male, NA, stage:, alive, 272 days
479.9
DO32860
0 years, male, NA, stage:, dead, 1259 days
472.3
DO34288
0 years, female, NA, stage:, dead, 220 days
470.1
DO49137
0 years, female, NA, stage:, alive, 232 days
467.8
DO49127
0 years, female, NA, stage:, alive, 392 days
464.6
DO49178
0 years, male, NA, stage:, dead, 27 days
449.2
DO33512
female, NA, stage:, dead, 499 days
446.4
DO34801
0 years, male, NA, stage:, alive, 626 days
436.1
DO34736
0 years, female, NA, stage:, dead, 203 days
434.7
DO32863
0 years, male, NA, stage:, dead, 715 days
434.2
DO33984
0 years, male, NA, stage:, alive, 847 days
434.1
DO34656
0 years, female, NA, stage:, alive, 834 days
432.3
DO49129
0 years, male, NA, stage:, alive, 337 days
425.3
DO49133
0 years, female, NA, stage:, alive, 188 days
406.4
DO34809
0 years, female, NA, stage:, dead, 297 days
401.3
DO49090
0 years, female, NA, stage:, dead, 152 days
400.5
DO49170
0 years, male, NA, stage:, alive, 197 days
392.9
DO34640
0 years, female, NA, stage:, dead, 287 days
392.8
DO33552
0 years, female, NA, stage:, alive, 873 days
367.9
DO33392
0 years, male, NA, stage:, alive, 1014 days
362.8
DO34696
0 years, male, NA, stage:, alive, 689 days
361.6
DO33480
0 years, male, NA, stage:, alive, 1054 days
357.7
DO32878
0 years, female, NA, stage:, dead, 260 days
352.7
DO34368
0 years, female, NA, stage:, dead, 537 days
344.7
DO49166
0 years, female, NA, stage:, alive, 222 days
341.3
DO49076
0 years, male, NA, stage:, dead, 480 days
332.8
DO33488
0 years, male, NA, stage:, alive, 844 days
322.5
DO33408
0 years, female, NA, stage:, alive, 909 days
316.6
DO32875
0 years, male, NA, stage:, dead, 348 days
311.7
DO34793
0 years, male, NA, stage:, dead, 427 days
300.6
DO34728
0 years, female, NA, stage:, alive, 508 days
297.1
DO34608
0 years, female, NA, stage:, dead, 709 days
295.7
DO34600
0 years, male, NA, stage:, dead, 537 days
290.4
DO34849
0 years, female, NA, stage:, dead, 272 days
287.8
DO34240
0 years, male, NA, stage:, dead, 236 days
285.5
DO32829
0 years, female, NA, stage:T2N0MX, dead, 1874 days
280.7
DO49087
0 years, female, NA, stage:, dead, 260 days
275.2
DO34448
0 years, female, NA, stage:, dead, 719 days
274.3
DO33168
0 years, female, NA, stage:, dead, 8 days
272.5
DO49130
0 years, female, NA, stage:, alive, 351 days
263.6
DO34720
0 years, male, NA, stage:, alive, 555 days
255.2
DO49185
0 years, male, NA, stage:, alive, 179 days
253.3
DO49078
0 years, male, NA, stage:, dead, 465 days
249.2
DO49113
0 years, female, NA, stage:, alive, 413 days
245.6
DO33376
0 years, female, NA, stage:, alive, 909 days
238.1
DO34312
0 years, female, NA, stage:, dead, 226 days
236.5
DO49138
0 years, male, NA, stage:, dead, 230 days
216.6
DO33128
0 years, male, NA, stage:, dead, 423 days
196.3
DO49181
0 years, male, NA, stage:, dead, 1534 days
194.9
DO34432
0 years, female, NA, stage:, dead, 400 days
194.6
DO49135
0 years, male, NA, stage:, alive, 270 days
188.1
DO33544
0 years, female, NA, stage:, dead, 412 days
176.2
DO33336
0 years, female, NA, stage:, dead, 451 days
169.3
DO32900
0 years, male, NA, stage:, dead, 768 days
168.1
DO33344
0 years, male, NA, stage:, dead, 361 days
166.0
DO49183
0 years, female, NA, stage:, dead, 429 days
161.4
DO33472
0 years, female, NA, stage:, dead, 388 days
147.2
DO33600
0 years, female, NA, stage:, alive, 854 days
122.0
DO49074
0 years, male, NA, stage:, dead, 168 days
112.8
DO49172
0 years, female, NA, stage:, dead, 1021 days
108.5
DO49199
0 years, male, NA, stage:, dead, 1095 days
86.9
DO49198
0 years, female, NA, stage:, dead, 251 days
68.0
DO49175
0 years, male, NA, stage:, dead, 414 days
53.4
DO49184
0 years, male, NA, stage:, dead, 455 days
39.7
DO34336
0 years, female, NA, stage:, alive, 743 days
6.2
Show allShow less
PANCREATIC DUCTAL ADENOCARCINOMA - Protein relative expression (CPTAC)
Number of samples
235
Samples
Sample ID
Sample type
nRPX
CPT0238740004
Normal
1.8
CPT0183770004
Normal
1.6
CPT0198930003
Normal
1.3
CPT0238940004
Normal
1.2
CPT0208850004
Normal
0.9
CPT0198440004
Normal
0.8
CPT0347820002
Normal
0.7
CPT0347880002
Normal
0.7
CPT0187540004
Normal
0.7
CPT0238640004
Normal
0.7
CPT0276030003
Normal
0.6
CPT0347850002
Normal
0.6
CPT0208710004
Normal
0.6
CPT0246220004
Normal
0.6
CPT0174800003
Normal
0.6
CPT0246950003
Normal
0.6
CPT0248440003
Normal
0.6
CPT0127290003
Normal
0.6
C3N-02573-03
Normal
0.6
CPT0237920004
Normal
0.5
CPT0347760002
Normal
0.5
CPT0162780004
Normal
0.5
CPT0236800004
Normal
0.5
C3L-00401-04
Normal
0.5
CPT0209650004
Normal
0.5
CPT0170240004
Tumor
0.4
CPT0064570003
Normal
0.4
CPT0239140004
Normal
0.4
CPT0218220004
Normal
0.4
CPT0170260004
Normal
0.4
KoreanReference1
Tumor
0.3
CPT0197420004
Tumor
0.3
CPT0247000003
Normal
0.3
CPT0198420004
Tumor
0.3
CPT0226490004
Tumor
0.3
CPT0109300004
Tumor
0.3
CPT0025760003
Normal
0.3
CPT0238040005
Tumor
0.3
CPT0197440004
Normal
0.2
CPT0187550004
Tumor
0.2
CPT0089750004
Normal
0.2
CPT0123650003
Tumor
0.2
CPT0246210004
Tumor
0.2
CPT0355200003
Normal
0.2
CPT0019300004
Tumor
0.2
CPT0077810003
Normal
0.2
CPT0239920004
Normal
0.2
CPT0236710004
Normal
0.2
CPT0166780004
Normal
0.2
C3N-00709-06
Normal
0.2
CPT0224460004
Tumor
0.1
CPT0109010004
Tumor
0.1
KoreanReference2
Tumor
0.1
CPT0226530004
Tumor
0.1
CPT0238440005
Tumor
0.1
CPT0239910004
Tumor
0.1
CPT0239100009
Tumor
0.1
CPT0236340004
Tumor
0.1
CPT0094630004
Tumor
0.1
CPT0264150003
Tumor
0.1
CPT0185920004
Tumor
0.1
CPT0209640005
Tumor
0.1
CPT0207780004
Tumor
0.1
CPT0207980005
Tumor
0.1
CPT0019410004
Tumor
0.1
CPT0094230004
Tumor
0.1
CPT0063580003
Normal
0.1
CPT0008750003
Tumor
0.1
CPT0247090003
Tumor
0.1
C3L-03632-04
Normal
0.0
CPT0355180003
Normal
0.0
CPT0138990003
Normal
0.0
CPT0065640003
Tumor
0.0
WU-PDA1
Tumor
0.0
CPT0226680005
Tumor
0.0
CPT0347790002
Normal
0.0
CPT0108400003
Tumor
0.0
CPT0064110003
Normal
0.0
CPT0238920004
Tumor
0.0
CPT0236780005
Tumor
0.0
CPT0241510004
Normal
0.0
CPT0237270005
Tumor
0.0
CPT0236700005
Tumor
0.0
CPT0077930004
Tumor
0.0
CPT0246990003
Tumor
0.0
CPT0248620003
Normal
0.0
CPT0183450005
Tumor
0.0
CPT0162660004
Tumor
0.0
CPT0236560004
Tumor
0.0
CPT0162760003
Tumor
0.0
CPT0183750005
Tumor
0.0
CPT0078090004
Tumor
0.0
CPT0217700004
Tumor
0.0
CPT0011540003
Normal
0.0
CPT0000250017
Tumor
-0.1
CPT0123670003
Normal
-0.1
CPT0355190003
Normal
-0.1
CPT0025750003
Tumor
-0.1
CPT0123770003
Normal
-0.1
CPT0209310004
Tumor
-0.1
CPT0161770004
Tumor
-0.1
CPT0236360004
Normal
-0.1
CPT0246840003
Tumor
-0.1
CPT0186040004
Tumor
-0.1
CPT0221470005
Tumor
-0.1
CPT0124360003
Tumor
-0.1
CPT0123860003
Tumor
-0.1
CPT0124500004
Tumor
-0.1
CPT0203850004
Tumor
-0.1
CPT0237910004
Tumor
-0.1
CPT0078180003
Normal
-0.1
CPT0088180004
Tumor
-0.1
CPT0226610004
Normal
-0.1
CPT0218200004
Tumor
-0.1
CPT0238820005
Tumor
-0.1
CPT0208550005
Tumor
-0.1
CPT0238710004
Tumor
-0.1
CPT0226760004
Tumor
-0.1
CPT0077950003
Normal
-0.1
CPT0237850004
Normal
-0.1
CPT0207990004
Normal
-0.1
CPT0246720003
Tumor
-0.2
CPT0124530003
Normal
-0.2
CPT0078030003
Normal
-0.2
CPT0123990003
Tumor
-0.2
CPT0081470004
Tumor
-0.2
C3L-00189-04
Normal
-0.2
CPT0094030003
Tumor
-0.2
CPT0237840004
Tumor
-0.2
CPT0246940003
Tumor
-0.2
CPT0198700005
Tumor
-0.2
CPT0187930005
Tumor
-0.2
CPT0091680003
Normal
-0.2
CPT0094130004
Tumor
-0.2
CPT0088260004
Tumor
-0.2
CPT0008800003
Tumor
-0.2
CPT0094940004
Tumor
-0.2
CPT0227930004
Tumor
-0.2
CPT0208840004
Tumor
-0.2
CPT0093880003
Normal
-0.2
CPT0166760004
Tumor
-0.2
CPT0221240004
Tumor
-0.2
CPT0123460003
Normal
-0.2
CPT0081360004
Tumor
-0.2
CPT0066020003
Normal
-0.2
CPT0081060004
Tumor
-0.2
CPT0094180003
Tumor
-0.3
CPT0241320005
Tumor
-0.3
CPT0124410004
Tumor
-0.3
CPT0208690004
Tumor
-0.3
CPT0246810003
Tumor
-0.3
CPT0248410004
Tumor
-0.3
CPT0091660003
Tumor
-0.3
CPT0248590004
Tumor
-0.3
CPT0235230004
Tumor
-0.3
CPT0063970004
Tumor
-0.3
CPT0226650004
Tumor
-0.3
CPT0124610004
Tumor
-0.3
CPT0014040003
Tumor
-0.3
CPT0241500004
Tumor
-0.3
CPT0064090003
Tumor
-0.3
CPT0238610009
Tumor
-0.3
CPT0162670004
Normal
-0.3
CPT0063570003
Tumor
-0.3
CPT0088320003
Tumor
-0.3
CPT0226570004
Tumor
-0.3
CPT0093930004
Tumor
-0.3
CPT0123440003
Tumor
-0.3
CPT0126160004
Tumor
-0.3
CPT0161990005
Tumor
-0.3
CPT0226600004
Tumor
-0.4
CPT0078250003
Tumor
-0.4
CPT0065570003
Tumor
-0.4
CPT0198910005
Tumor
-0.4
CPT0254680003
Tumor
-0.4
CPT0276010003
Tumor
-0.4
CPT0001730017
Tumor
-0.4
KoreanReference3
Tumor
-0.4
CPT0125090003
Tumor
-0.4
CPT0089720003
Tumor
-0.4
CPT0092630003
Tumor
-0.4
CPT0078000003
Tumor
-0.4
CPT0078160004
Tumor
-0.4
CPT0017040004
Tumor
-0.4
CPT0094740004
Tumor
-0.4
CPT0093860003
Tumor
-0.5
CPT0081260004
Tumor
-0.5
CPT0123750003
Tumor
-0.5
CPT0001750003
Normal
-0.5
CPT0011520003
Tumor
-0.5
CPT0077880003
Normal
-0.5
CPT0123890003
Normal
-0.5
CPT0125130003
Tumor
-0.5
CPT0108960003
Normal
-0.5
CPT0086210003
Normal
-0.5
CPT0238530005
Tumor
-0.5
CPT0109200004
Tumor
-0.6
CPT0083270003
Tumor
-0.6
CPT0246260004
Tumor
-0.6
CPT0139000004
Tumor
-0.6
CPT0124000003
Normal
-0.6
CPT0174700004
Tumor
-0.7
CPT0093980004
Tumor
-0.7
CPT0077790004
Tumor
-0.7
CPT0108930003
Tumor
-0.7
CPT0247040003
Tumor
-0.7
CPT0077860003
Tumor
-0.7
CPT0017130003
Normal
-0.7
CPT0086190004
Tumor
-0.7
CPT0127270003
Tumor
-0.7
CPT0125010003
Normal
-0.8
CPT0087890004
Tumor
-0.8
CPT0124980004
Tumor
-0.8
CPT0221250004
Normal
-0.8
CPT0064520004
Tumor
-0.9
CPT0247050003
Normal
N/A
CPT0108410003
Normal
N/A
CPT0248320003
Normal
N/A
CPT0166650006
Tumor
N/A
CPT0224470004
Normal
N/A
C3L-01687-04
Normal
N/A
CPT0138890003
Normal
N/A
CPT0109110004
Tumor
N/A
WU-pooled sample
Tumor
N/A
CPT0014060003
Normal
N/A
CPT0109130003
Normal
N/A
CPT0138900004
Tumor
N/A
CPT0166680004
Normal
N/A
CPT0094760003
Normal
N/A
CPT0186050004
Normal
N/A
CPT0237290004
Normal
N/A
CPT0264180003
Normal
N/A
CPT0063990003
Normal
N/A
CPT0126200003
Normal
N/A
CPT0198730004
Normal
N/A
Show allShow less
PANCREATIC CANCER - Protein expressioni
A mouse-over function shows sample information and annotation data. Click on an image to view it in a full screen mode. Samples can be filtered based on level of antibody staining by selecting one or several of the following categories: high, medium, low and not detected. The assay and annotation is described here.
Note that samples used for immunohistochemistry by the Human Protein Atlas do not correspond to samples in the TCGA dataset.
Antibody stainingi
Antibody staining in the annotated cell types in the current human tissue is reported as not detected, low, medium, or high, based on conventional immunohistochemistry profiling in selected tissues. This score is based on the combination of the staining intensity and fraction of stained cells.
Each image is clickable and will lead to virtual microscopy that enables deeper exploration of all samples and also displays staining intensity scores, fraction scores and subcellular localization as well as patient and tissue information for each sample.