We use cookies to enhance the usability of our website. If you continue, we'll assume that you are happy to receive all cookies. More information. Don't show this again.
The Survival Scatter plot shows the clinical status (i.e. dead or alive) for all individuals in the patient cohort, based on the same data that underlies the corresponding Kaplan-Meier plots. Patients that are alive at last time for follow-up are shown in blue and patients who have died during the study are shown in red.
The x-axis shows the expression levels (FPKM) of the investigated gene in the tumor tissue at the time of diagnosis. The y-axis shows the follow-up time after diagnosis (years). Both axes are complimented with kernel density curves demonstrating the data density over the axes. The top density plot shows the expression levels (FPKM) distribution among dead (red) and alive patients (blue). The right density plot shows the data density of the survived years of dead patients with high and low expression levels respectively, stratified using the cutoff indicated by the vertical dashed line through the Survival Scatter plot. This cutoff is automatically defined based on the FPKM cutoff that minimizes the p-score. The cutoff can be changed by dragging the vertical line or by entering a cutoff value in the square labeled "Current cut-off".
Under the Survival Scatter plot the p-score landscape (black curve; left axis) is shown together with dead median separation (red curve; right axis). Dead median separation is the difference in median mRNA expression between patients who have died with high and low expression, respectively. It is calculated as follows: median FPKM expression of dead patients with high expression - median FPKM expression of dead patients with low expression. This is intended to aid the user in visually exploring custom cutoffs and the associated p-scores and dead median separation.
Individual patient data is displayed and can be filtered by clicking on one or more of the category buttons on the top of the page. Categories describing expression level and patient information include: high, low, alive, dead, female, male and tumor stages. The scale of the x-axis can be toggled between linear and log-scale by clicking on the "x log" button. Mouse-over function shows TCGA ID, patient information and mRNA expression (FPKM) for each patient.
& Survival analysisi
Kaplan-Meier plots summarize results from analysis of correlation between mRNA expression level and patient survival. Patients were divided based on level of expression into one of the two groups "low" (under cut off) or "high" (over cut off). X-axis shows time for survival (years) and y-axis shows the probability of survival, where 1.0 corresponds to 100 percent.
MT2A is not prognostic in Testicular Germ Cell Tumor (TCGA)
Stage:
Survival analysis
Current cut offi
Current cut-off shows the cut-off (FPKM) currently selected. It may be changed manually. When the current cut-off is changed, the vertical dashed line indicating cut-off, the interactive survival scatter plot and the Kaplan-Meier curve will be automatically adjusted to show results accordingly.
:
Best expression cut offi
Based on the FPKM value of each gene, patients were classified into two groups and association between prognosis (survival) and gene expression (FPKM) was examined. The best expression cut-off refers the FPKM value that yields maximal difference with regard to survival between the two groups at the lowest log-rank P-value. Best expression cut-off was selected based on survival analysis .
When clicking on this number, the vertical dashed line indicating cut-off, the interactive survival plot, and the Kaplan-Meier curve will be adjusted to show results based on the best expression cut-off.
Median expression refers to the median FPKM value calculated based on the gene expression (FPKM) data from all patients in this dataset. When clicking on this number, the vertical dashed line indicating cut-off, the interactive survival plot, and the Kaplan-Meier curve will be adjusted to show results based on the median expression.
Median follow up time refers to the median time (years) after diagnosis with this type of cancer, based on clinical data from all patients in this dataset.
: N/A
P scorei
Log-rank P value for Kaplan-Meier plot showing results from analysis of correlation between mRNA expression level and patient survival.
N/A
5-year survival highi
5-year survival for patients with higher expression than the expression cutoff.
For melanoma and glioma, 3-year survival is shown.
N/A
5-year survival lowi
5-year survival for patients with lower expression than the expression cutoff.
For melanoma and glioma, 3-year survival is shown.
N/A
TCGA RNA samplesi
RNA-seq data is reported as average FPKM (number Fragments Per Kilobase of exon per Million reads), generated by the The Cancer Genome Atlas (TCGA) .
Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. FPKM values of the individual samples are presented next to the box plot.
Average TPM
832.5
Number of samples
133
Samples
Sample
Description
TPM
TCGA-2G-AAKM-01A
0 years, male, white, stage:Stage II, dead, 6972 days
7076.2
TCGA-2G-AAGF-01A
0 years, male, white, stage:Stage IS, alive, 2734 days
6981.4
TCGA-2G-AAKL-01A
0 years, male, white, stage:Stage II, alive, 7023 days
4193.9
TCGA-ZM-AA05-01A
0 years, male, white, stage:Stage IIC, alive, 1126 days
3430.2
TCGA-2G-AAG8-01A
0 years, male, white, stage:Stage IB, alive, 2289 days
3244.3
TCGA-2G-AAGA-01A
0 years, male, white, stage:Stage IIA, alive, 2439 days
3140.8
TCGA-2G-AAGW-01A
0 years, male, white, stage:Stage IS, alive, 4899 days
2939.3
TCGA-VF-A8AB-01A
0 years, male, black or african american, stage:Stage IA, alive, 760 days
2902.6
TCGA-XY-A8S2-01A
0 years, male, white, stage:Stage I, alive, 672 days
2645.6
TCGA-2G-AAGS-01A
0 years, male, white, stage:Stage IIIB, alive, 4816 days
2565.1
TCGA-2G-AAFL-01A
0 years, male, white, stage:Stage IB, alive, 750 days
2492.8
TCGA-2G-AAKD-01A
0 years, male, white, stage:Stage III, alive, 6340 days
2482.7
TCGA-2G-AAGK-01A
0 years, male, white, stage:Stage IS, alive, 3621 days
2355.3
TCGA-2G-AAGE-01A
0 years, male, white, stage:Stage IS, alive, 2478 days
1986.2
TCGA-YU-A90P-01A
0 years, male, white, stage:Stage IA, alive, 2069 days
1963.3
TCGA-2G-AAL7-01A
0 years, male, white, stage:Stage IS, alive, 3991 days
1870.7
TCGA-2G-AAG0-01A
0 years, male, white, stage:Stage IS, alive, 1529 days
1866.1
TCGA-2G-AAFN-01A
0 years, male, white, stage:Stage IIIB, alive, 773 days
1762.0
TCGA-2G-AALP-01A
0 years, male, white, stage:Stage IIIB, alive, 2645 days
1742.4
TCGA-X3-A8G4-01A
0 years, male, white, stage:Stage IS, alive, 856 days
1657.0
TCGA-2G-AAGN-01A
0 years, male, white, stage:Stage IIIB, alive, 3656 days
1643.4
TCGA-2G-AAG7-01A
0 years, male, white, stage:Stage IS, alive, 2475 days
1634.7
TCGA-2G-AAGJ-01A
0 years, male, black or african american, stage:Stage IA, alive, 2938 days
1531.8
TCGA-2G-AAFM-01A
0 years, male, white, stage:Stage IIA, alive, 503 days
1483.2
TCGA-2G-AAKG-01A
0 years, male, white, stage:Stage I, alive, 6598 days
1454.3
TCGA-2G-AAFO-01A
0 years, male, white, stage:Stage IIA, alive, 685 days
1450.9
TCGA-VF-A8A8-01A
0 years, male, white, stage:Stage IA, alive, 1131 days
1277.3
TCGA-2G-AAHC-01A
0 years, male, white, stage:Stage IS, alive, 5539 days
1253.6
TCGA-VF-A8AD-01A
0 years, male, white, stage:Stage IB, alive, 1006 days
1193.0
TCGA-2G-AAFY-01A
0 years, male, white, stage:Stage IIA, alive, 1099 days
1119.6
TCGA-4K-AAAL-01A
0 years, male, white, stage:Stage IS, alive, 483 days
1045.0
TCGA-2G-AAGO-01A
0 years, male, white, stage:Stage IS, alive, 4026 days
1026.9
TCGA-2G-AAFI-01A
0 years, male, white, stage:Stage IB, alive, 675 days
1010.2
TCGA-SN-A84Y-01A
0 years, male, white, stage:Stage IS, alive, 524 days
999.4
TCGA-2G-AAH2-01A
0 years, male, white, stage:Stage IS, alive, 6060 days
916.3
TCGA-2G-AAHP-01A
0 years, male, white, stage:Stage IS, alive, 5667 days
887.3
TCGA-2G-AAGC-01A
0 years, male, white, stage:Stage IS, alive, 2585 days
865.6
TCGA-S6-A8JX-01A
0 years, male, white, stage:Stage IB, alive, 552 days
865.3
TCGA-XE-A9SE-01A
0 years, male, white, stage:Stage IA, alive, 708 days
778.4
TCGA-2G-AAEX-01A
0 years, male, white, stage:Stage IS, alive, 1259 days
777.8
TCGA-2G-AAGZ-01A
0 years, male, white, stage:Stage IIIA, alive, 5233 days
739.1
TCGA-YU-A90Y-01A
0 years, male, black or african american, stage:Stage IIIC, dead, 17 days
734.7
TCGA-XE-AAOB-01A
0 years, male, white, stage:Stage IS, dead, 513 days
698.6
TCGA-YU-A90S-01A
0 years, male, white, stage:Stage IA, alive, 971 days
633.5
TCGA-XE-A8H1-01A
0 years, male, white, stage:Stage IS, alive, 209 days
627.9
TCGA-2G-AAHG-01A
0 years, male, white, stage:Stage I, alive, 1819 days
596.0
TCGA-SN-A84X-01A
0 years, male, white, stage:Stage IS, alive, 312 days
586.9
TCGA-W4-A7U4-01A
0 years, male, white, stage:'--, alive, 738 days
583.9
TCGA-XE-AANJ-01A
0 years, male, white, stage:Stage IS, alive, 2007 days
568.2
TCGA-2G-AAHA-01A
0 years, male, white, stage:Stage IB, alive, 3349 days
567.0
TCGA-2G-AAG5-01A
0 years, male, white, stage:Stage IS, alive, 2299 days
563.4
TCGA-2G-AAGT-01A
0 years, male, white, stage:Stage IS, alive, 4406 days
562.5
TCGA-ZM-AA0H-01A
0 years, male, white, stage:Stage IS, alive, 1736 days
559.7
TCGA-2G-AAHN-01A
0 years, male, white, stage:Stage I, alive, 6445 days
534.3
TCGA-YU-AA61-01A
0 years, male, white, stage:Stage IS, alive, 864 days
534.0
TCGA-XE-A8H4-01A
0 years, male, white, stage:Stage IA, alive, 559 days
513.9
TCGA-2G-AAKH-01A
0 years, male, white, stage:Stage II, alive, 6862 days
489.7
TCGA-4K-AA1H-01A
0 years, male, white, stage:Stage IA, alive, 518 days
483.6
TCGA-2G-AAGP-01A
0 years, male, white, stage:Stage IIA, alive, 4018 days
482.8
TCGA-XE-AAO3-01A
0 years, male, asian, stage:Stage I, alive, 2857 days
482.6
TCGA-XE-AAOF-01A
0 years, male, asian, stage:Stage IA, alive, 1268 days
454.1
TCGA-SN-A6IS-01A
0 years, male, white, stage:Stage IS, alive, 496 days
431.2
TCGA-XY-A9T9-01A
0 years, male, white, stage:Stage IS, alive, 281 days
419.8
TCGA-W4-A7U3-01A
0 years, male, white, stage:'--, alive, 149 days
417.9
TCGA-2G-AAHT-01A
0 years, male, white, stage:Stage IS, alive, 542 days
415.4
TCGA-2G-AAFG-01A
0 years, male, white, stage:Stage IS, alive, 6183 days
392.8
TCGA-YU-AA4L-01A
0 years, male, black or african american, stage:Stage IIIC, alive, 1573 days
389.4
TCGA-XE-AAO6-01A
0 years, male, white, stage:Stage IA, alive, 240 days
384.4
TCGA-ZM-AA0D-01A
0 years, male, white, stage:Stage IA, alive, 848 days
381.1
TCGA-S6-A8JY-01A
0 years, male, white, stage:Stage IS, alive, 278 days
359.6
TCGA-4K-AA1G-01A
0 years, male, white, stage:Stage IS, alive, 436 days
350.8
TCGA-VF-A8AE-01A
0 years, male, white, stage:Stage IA, alive, 727 days
348.4
TCGA-VF-A8AC-01A
0 years, male, white, stage:Stage IA, alive, 1083 days
323.4
TCGA-WZ-A7V3-01A
0 years, male, white, stage:Stage I, alive, 753 days
318.7
TCGA-XY-A89B-01A
0 years, male, white, stage:Stage IA, alive, 471 days
317.1
TCGA-2G-AAGG-01A
0 years, male, white, stage:Stage IIIC, alive, 2611 days
313.4
TCGA-2G-AAGI-01A
0 years, male, white, stage:Stage IS, alive, 3137 days
312.3
TCGA-2G-AAFE-01A
0 years, male, white, stage:Stage IIA, alive, 4702 days
312.2
TCGA-4K-AA1I-01A
0 years, male, white, stage:Stage IA, alive, 3 days
306.6
TCGA-ZM-AA0F-01A
0 years, male, white, stage:Stage IA, alive, 681 days
303.5
TCGA-XE-AAOD-01A
0 years, male, white, stage:Stage IB, alive, 2058 days
297.0
TCGA-YU-A912-01A
0 years, male, black or african american, stage:Stage IIIC, alive, 866 days
289.3
TCGA-ZM-AA06-01A
0 years, male, white, stage:Stage IB, alive, 1498 days
281.7
TCGA-2G-AAG6-01A
0 years, male, white, stage:Stage IS, alive, 2231 days
276.3
TCGA-2G-AAFH-01A
0 years, male, white, stage:Stage IIB, alive, 1375 days
265.1
TCGA-WZ-A8D5-01A
0 years, male, white, stage:'--, alive, 774 days
264.6
TCGA-2G-AAHL-01A
0 years, male, white, stage:Stage I, alive, 7081 days
250.3
TCGA-2G-AAH0-01A
0 years, male, white, stage:Stage IS, alive, 5477 days
246.6
TCGA-2G-AAFZ-01A
0 years, male, white, stage:Stage III, alive, 1353 days
243.7
TCGA-2G-AAFV-01A
0 years, male, white, stage:Stage IS, alive, 1389 days
241.9
TCGA-2G-AAGX-01A
0 years, male, white, stage:Stage IA, alive, 5514 days
238.9
TCGA-2G-AAEW-01A
0 years, male, white, stage:Stage IS, dead, 618 days
236.7
TCGA-ZM-AA0B-01A
0 years, male, white, stage:Stage IA, alive, 838 days
228.7
TCGA-XE-AAOC-01A
0 years, male, white, stage:Stage IA, alive, 270 days
227.9
TCGA-XE-A8H5-01A
0 years, male, stage:Stage IS, alive, 1217 days
222.6
TCGA-2G-AAF1-01A
0 years, male, asian, stage:Stage IS, alive, 1403 days
212.3
TCGA-ZM-AA0E-01A
0 years, male, white, stage:Stage IA, alive, 811 days
211.8
TCGA-2G-AAH8-01A
0 years, male, white, stage:Stage IIIC, alive, 2248 days
206.0
TCGA-2G-AAF8-01A
0 years, male, white, stage:Stage IA, alive, 3911 days
205.9
TCGA-YU-A90W-01A
0 years, male, white, stage:Stage IA, alive, 1113 days
194.0
TCGA-2G-AAG9-01A
0 years, male, white, stage:Stage IIIB, alive, 2234 days
193.6
TCGA-W4-A7U2-01A
0 years, male, white, stage:'--, alive, 1263 days
193.4
TCGA-YU-A90Q-01A
0 years, male, stage:Stage IB, alive, 1964 days
187.8
TCGA-VF-A8A9-01A
0 years, male, white, stage:Stage IA, alive, 1119 days
180.4
TCGA-VF-A8AA-01A
0 years, male, white, stage:Stage I, alive, 1146 days
179.2
TCGA-2G-AAF4-01A
0 years, male, white, stage:Stage I, alive, 2315 days
178.4
TCGA-XE-AANV-01A
0 years, male, stage:Stage IB, alive, 1701 days
176.8
TCGA-XE-AANR-01A
0 years, male, white, stage:Stage I, alive, 14 days
172.9
TCGA-SB-A6J6-01A
0 years, male, white, stage:Stage IA, alive, 413 days
168.6
TCGA-WZ-A7V4-01A
0 years, male, white, stage:Stage I, alive, 894 days
165.9
TCGA-2G-AAH3-01A
0 years, male, white, stage:Stage I, alive, 1822 days
163.4
TCGA-ZM-AA0N-01A
0 years, male, white, stage:Stage IB, alive, 634 days
160.3
TCGA-XE-AAO4-01A
0 years, male, white, stage:Stage IA, alive, 367 days
159.5
TCGA-2X-A9D6-01A
0 years, male, white, stage:Stage I, alive, 607 days
150.1
TCGA-SB-A76C-01A
0 years, male, white, stage:'--, alive, 42 days
148.0
TCGA-2G-AAF6-01A
0 years, male, white, stage:Stage IS, alive, 3491 days
146.6
TCGA-2X-A9D5-01A
0 years, male, white, stage:Stage I, alive, 435 days
144.0
TCGA-SO-A8JP-01A
0 years, male, white, stage:Stage I, alive, 540 days
143.4
TCGA-XE-AAOL-01A
0 years, male, black or african american, stage:Stage I, alive, 13 days
143.2
TCGA-XE-AANI-01A
0 years, male, white, stage:Stage IS, alive, 1041 days
134.9
TCGA-2G-AAGV-01A
0 years, male, white, stage:'--, alive, 4527 days
132.9
TCGA-2G-AAG3-01A
0 years, male, white, stage:Stage IS, alive, 1593 days
132.3
TCGA-2G-AAL5-01A
0 years, male, white, stage:Stage I, alive, 7437 days
128.2
TCGA-WZ-A7V5-01A
0 years, male, white, stage:Stage I, alive, 1061 days
126.6
TCGA-2G-AAH4-01A
0 years, male, white, stage:Stage II, alive, 6210 days
122.2
TCGA-2G-AAGM-01A
0 years, male, white, stage:Stage IS, alive, 3891 days
116.1
TCGA-YU-A94I-01A
0 years, male, stage:Stage IA, alive, 536 days
113.1
TCGA-S6-A8JW-01A
0 years, male, white, stage:Stage IS, alive, 698 days
93.3
TCGA-2G-AAFJ-01A
0 years, male, asian, stage:'--, alive, 792 days
78.9
TCGA-SN-A84W-01A
0 years, male, white, stage:Stage IS, alive, 293 days
71.8
TCGA-2G-AAGY-01A
0 years, male, white, stage:Stage IS, alive, 5329 days
70.2
TCGA-XE-AAOJ-01A
0 years, male, white, stage:Stage IS, alive, 1550 days
68.2
TCGA-YU-A94D-01A
0 years, male, stage:Stage IIIB, alive, 2167 days
40.5
Show allShow less
TESTIS CANCER - Protein expressioni
A mouse-over function shows sample information and annotation data. Click on an image to view it in a full screen mode. Samples can be filtered based on level of antibody staining by selecting one or several of the following categories: high, medium, low and not detected. The assay and annotation is described here.
Note that samples used for immunohistochemistry by the Human Protein Atlas do not correspond to samples in the TCGA dataset.