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The primary data page shows the detailed antibody staining in 76 different cell types for each analyzed antibody. In addition, for each cell type, a knowledge-based annotated protein expression score based on all analyzed antibodies is displayed furthest to the right. The images and annotations can be accessed by clicking on the tissue name or score bar. More information can be found in Assays & Annotation.
The tissues and cell types can be ordered by organ, cell type or alphabetically. If ordered by organ, the tissues are presented in groups according to functional features. If ordered by cell type, the cells are presented in groups related to origin.
This score describes the level of antibody staining observed in the annotated cell types as not detected (n), low (l), medium (m) or high (h). It is based on the staining intensity and fraction of stained cells. The images and annotations can be accessed by clicking on the tissue name or score bar. More information can be found in Assays & Annotation.
Annotated protein expressioni
This score describes a knowledge-based best estimate of the protein expression in the annotated cell types as not detected (n), low (l), medium (m) or high (h). It is a result of stringent evaluation of immunohistochemical staining pattern, RNA data from internal and external sources and available protein/gene characterization data. More information can be found in Assays & Annotation.
Summarizing texts describe the staining pattern for each antibody based on staining intensity, fraction of stained cells and subcellular localization. More information can be found in Assays & Annotation.
HPA041838
Normal tissues displayed moderate to strong cytoplasmic positivity with additional membranous and nucleolar staining in several tissues. Liver, lymph node, smooth muscle and endometrial stroma were weakly stained or negative.
HPA048257
Normal tissues displayed moderate to strong nuclear and/or cytoplasmic staining. Additional cytoplasmic membranous positivity was observed in small intestine, duodenum, epididymis, fallopian tube and salivary gland. Glandular cells of breast, Purkinje cells, liver cells and Islets of Langerhans were weakly stained.
CAB070171
Most normal tissues showed moderate nuclear positivity with additional cytoplasmic staining in several cases. Renal tubules and Leydig cells were strongly stained. Squamous cells in skin and vagina displayed strong nuclear immunoreactivity. Bile ducts and parathyroid were weakly stained.
The Human Protein Atlas project is funded
