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The primary data page shows the detailed antibody staining in 76 different cell types for each analyzed antibody. In addition, for each cell type, a knowledge-based annotated protein expression score based on all analyzed antibodies is displayed furthest to the right. The images and annotations can be accessed by clicking on the tissue name or score bar. More information can be found in Assays & Annotation.
The tissues and cell types can be ordered by organ, cell type or alphabetically. If ordered by organ, the tissues are presented in groups according to functional features. If ordered by cell type, the cells are presented in groups related to origin.
This score describes the level of antibody staining observed in the annotated cell types as not detected (n), low (l), medium (m) or high (h). It is based on the staining intensity and fraction of stained cells. The images and annotations can be accessed by clicking on the tissue name or score bar. More information can be found in Assays & Annotation.
Annotated protein expressioni
This score describes a knowledge-based best estimate of the protein expression in the annotated cell types as not detected (n), low (l), medium (m) or high (h). It is a result of stringent evaluation of immunohistochemical staining pattern, RNA data from internal and external sources and available protein/gene characterization data. More information can be found in Assays & Annotation.
Summarizing texts describe the staining pattern for each antibody based on staining intensity, fraction of stained cells and subcellular localization. More information can be found in Assays & Annotation.
HPA006882
Glandular epithelia and lymphoid tissues generally displayed moderate cytoplasmic immunoreactivity. The staining was often accentuated to the plasma membrane. Strong positivity was observed in cytotrophoblasts of placenta and in macrophages. In stomach, extracellular portions of mucus-secreting cells showed positivity. Most other normal tissues were faintly stained or negative.
CAB037132
Most of the normal tissues displayed moderate to strong cytoplasmic positivity. Additional luminal membranous staining was observed in glandular tissues and renal tubules. Pneumocytes, ovarian and endometrial stroma, cells in CNS and soft tissues were negative.
CAB037147
Normal tissues showed moderate to strong membranous and cytoplasmic staining. Purkinje cells displayed moderate nuclear positivity. Hepatocytes, adrenal, cells in glomeruli, Leydig cells and the CNS tissues were negative.
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