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The primary data page shows the detailed antibody staining in 76 different cell types for each analyzed antibody. In addition, for each cell type, a knowledge-based annotated protein expression score based on all analyzed antibodies is displayed furthest to the right. The images and annotations can be accessed by clicking on the tissue name or score bar. More information can be found in Assays & Annotation.
The tissues and cell types can be ordered by organ, cell type or alphabetically. If ordered by organ, the tissues are presented in groups according to functional features. If ordered by cell type, the cells are presented in groups related to origin.
This score describes the level of antibody staining observed in the annotated cell types as not detected (n), low (l), medium (m) or high (h). It is based on the staining intensity and fraction of stained cells. The images and annotations can be accessed by clicking on the tissue name or score bar. More information can be found in Assays & Annotation.
Annotated protein expressioni
This score describes a knowledge-based best estimate of the protein expression in the annotated cell types as not detected (n), low (l), medium (m) or high (h). It is a result of stringent evaluation of immunohistochemical staining pattern, RNA data from internal and external sources and available protein/gene characterization data. More information can be found in Assays & Annotation.
Summarizing texts describe the staining pattern for each antibody based on staining intensity, fraction of stained cells and subcellular localization. More information can be found in Assays & Annotation.
HPA005823
Normal tissues displayed weak to moderate cytoplasmic staining with additional membranous positivity in few tissues. Hematopoietic cells, pneumocytes and cells in red pulp of spleen were strongly stained. Glial cells, neuronal cells and bile duct cells were negative.
HPA029560
Strong luminal membranous positivity was displayed in small intestinal glands. Renal tubules and hematopoietic cells showed strong cytoplasmic positivity. Purkinje cells were moderately stained. Moderate cytoplasmic and nuclear positivity was observed in Leydig cells. Extracellular material was distinctly stained. Remaining normal tissues were weakly stained or negative.
CAB007779
Normal cells generally displayed moderate cytoplasmic immunoreactivity. Renal glomeruli showed strong positivity in membranes and nuclei in addition to the cytoplasmic staining. Membranous positivity was also observed in prostate and gallbladder.
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