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The primary data page shows the detailed antibody staining in 76 different cell types for each analyzed antibody. In addition, for each cell type, a knowledge-based annotated protein expression score based on all analyzed antibodies is displayed furthest to the right. The images and annotations can be accessed by clicking on the tissue name or score bar. More information can be found in Assays & Annotation.
The tissues and cell types can be ordered by organ, cell type or alphabetically. If ordered by organ, the tissues are presented in groups according to functional features. If ordered by cell type, the cells are presented in groups related to origin.
This score describes the level of antibody staining observed in the annotated cell types as not detected (n), low (l), medium (m) or high (h). It is based on the staining intensity and fraction of stained cells. The images and annotations can be accessed by clicking on the tissue name or score bar. More information can be found in Assays & Annotation.
Annotated protein expressioni
This score describes a knowledge-based best estimate of the protein expression in the annotated cell types as not detected (n), low (l), medium (m) or high (h). It is a result of stringent evaluation of immunohistochemical staining pattern, RNA data from internal and external sources and available protein/gene characterization data. More information can be found in Assays & Annotation.
Summarizing texts describe the staining pattern for each antibody based on staining intensity, fraction of stained cells and subcellular localization. More information can be found in Assays & Annotation.
HPA041231
Moderate to strong cytoplasmic positivity was observed in normal tissues. Additional membranous staining was seen in adrenal, breast, bronchus, endocervical and endometrial glands, fallopian tube and urinary bladder. Lungs, hepatocytes, islets of Langerhans, glomeruli, CNS tissue and lymphoid tissue were negative.
HPA059883
Normal tissues showed moderate cytoplasmic staining. The neuronal cells of cerebral cortex, intestinal tract, lung macrophages, exocrine pancreas, thyroid and a subset of germinal center cells displayed strong positivity. Fallopian tube, gall bladder, stomach and urothelial cells displayed additional membranous immunoreactivity.
CAB005016
Most normal tissues showed moderate cytoplasmic staining. Several tissues including prostate and kidney showed additional nuclear positivity. Strong staining was observed in Langerhans islets, neurons, epididymis and the thyroid gland.
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