Expression of DYNLL1 in urothelial cancer

BLADDER UROTHELIAL CARCINOMA (TCGA) - Interactive survival scatter plotⁱ

The Survival Scatter plot shows the clinical status (i.e. dead or alive) for all individuals in the patient cohort, based on the same data that underlies the corresponding Kaplan-Meier plots. Patients that are alive at last time for follow-up are shown in blue and patients who have died during the study are shown in red.

The x-axis shows the expression levels (FPKM) of the investigated gene in the tumor tissue at the time of diagnosis. The y-axis shows the follow-up time after diagnosis (years). Both axes are complimented with kernel density curves demonstrating the data density over the axes. The top density plot shows the expression levels (FPKM) distribution among dead (red) and alive patients (blue). The right density plot shows the data density of the survived years of dead patients with high and low expression levels respectively, stratified using the cutoff indicated by the vertical dashed line through the Survival Scatter plot. This cutoff is automatically defined based on the FPKM cutoff that minimizes the p-score. The cutoff can be changed by dragging the vertical line or by entering a cutoff value in the square labeled "Current cut-off".

Under the Survival Scatter plot the p-score landscape (black curve; left axis) is shown together with dead median separation (red curve; right axis). Dead median separation is the difference in median mRNA expression between patients who have died with high and low expression, respectively. It is calculated as follows: median FPKM expression of dead patients with high expression - median FPKM expression of dead patients with low expression. This is intended to aid the user in visually exploring custom cutoffs and the associated p-scores and dead median separation.

Individual patient data is displayed and can be filtered by clicking on one or more of the category buttons on the top of the page. Categories describing expression level and patient information include: high, low, alive, dead, female, male and tumor stages. The scale of the x-axis can be toggled between linear and log-scale by clicking on the "x log" button. Mouse-over function shows TCGA ID, patient information and mRNA expression (FPKM) for each patient.

& Survival analysisⁱ

DYNLL1 is not prognostic in Bladder Urothelial Carcinoma (TCGA)

Stage:

Survival analysis

Current cut offⁱ :

Best expression cut offⁱ : 633.6

Median expressionⁱ : N/A

Median follow up timeⁱ : N/A

P scoreⁱ N/A

5-year survival highⁱ N/A

5-year survival lowⁱ N/A

TCGA RNA samplesⁱ

Average TPM

515.8

Number of samples

169

Samples

Sample	Description	TPM
TCGA-FD-A3N5-01A	69 years, male, black or african american, stage:Stage II, dead, 685 days	1123.4
TCGA-GV-A40E-01A	75 years, male, white, stage:Stage II, dead, 261 days	917.4
TCGA-XF-A9SZ-01A	79 years, male, white, stage:Stage IV, dead, 859 days	902.0
TCGA-FD-A62P-01A	76 years, male, white, stage:Stage II, dead, 191 days	869.3
TCGA-G2-A3IB-01A	66 years, male, black or african american, stage:Stage II, dead, 220 days	868.5
TCGA-FD-A5BX-01A	82 years, male, white, stage:Stage IV, dead, 173 days	866.9
TCGA-E7-A97P-01A	73 years, male, asian, stage:Stage II, dead, 437 days	849.6
TCGA-E5-A4TZ-01A	64 years, male, white, stage:Stage IV, dead, 467 days	840.0
TCGA-ZF-A9RN-01A	67 years, female, white, stage:Stage III, dead, 615 days	835.1
TCGA-BL-A3JM-01A	62 years, male, white, stage:Stage III, dead, 205 days	834.9
TCGA-FD-A6TD-01A	77 years, male, white, stage:Stage III, dead, 386 days	820.4
TCGA-ZF-AA5N-01A	62 years, female, white, stage:Stage IV, dead, 168 days	804.1
TCGA-FD-A3SM-01A	70 years, male, white, stage:Stage IV, dead, 547 days	803.5
TCGA-BT-A3PH-01A	76 years, male, white, stage:Stage IV, dead, 142 days	788.4
TCGA-DK-A1A5-01A	79 years, male, white, stage:Stage II, dead, 65 days	782.1
TCGA-4Z-AA80-01A	73 years, male, white, stage:Stage II, dead, 19 days	772.1
TCGA-ZF-A9RD-01A	75 years, female, white, stage:Stage IV, dead, 408 days	771.2
TCGA-DK-AA6L-01A	48 years, male, white, stage:Stage IV, dead, 1163 days	750.7
TCGA-FD-A3B5-01A	86 years, male, black or african american, stage:Stage IV, dead, 272 days	748.4
TCGA-DK-A1AB-01A	74 years, female, white, stage:Stage IV, dead, 508 days	734.8
TCGA-FJ-A871-01A	49 years, male, white, stage:Stage III, dead, 272 days	729.8
TCGA-C4-A0EZ-01A	69 years, female, stage:Stage IV, dead, 273 days	716.1
TCGA-4Z-AA86-01A	66 years, male, black or african american, stage:Stage IV, dead, 311 days	714.8
TCGA-5N-A9KI-01A	76 years, female, white, stage:Stage III, dead, 76 days	707.0
TCGA-FD-A3B3-01A	74 years, female, white, stage:Stage III, dead, 974 days	706.6
TCGA-ZF-AA56-01A	79 years, female, white, stage:Stage III, dead, 259 days	697.1
TCGA-E7-A3X6-01A	70 years, male, white, stage:Stage II, dead, 904 days	680.6
TCGA-BT-A20X-01A	56 years, male, white, stage:Stage IV, dead, 251 days	675.3
TCGA-XF-AAN7-01A	60 years, male, white, stage:Stage IV, dead, 565 days	673.5
TCGA-FD-A3B4-01A	55 years, female, black or african american, stage:Stage III, dead, 510 days	663.6
TCGA-GU-A767-01A	81 years, male, white, stage:Stage IV, dead, 144 days	661.3
TCGA-GU-A762-01A	87 years, male, white, stage:Stage IV, dead, 232 days	660.6
TCGA-XF-A9ST-01A	68 years, male, white, stage:Stage III, dead, 128 days	659.1
TCGA-ZF-AA4R-01A	67 years, male, white, stage:Stage IV, dead, 1036 days	658.4
TCGA-2F-A9KP-01A	66 years, male, white, stage:Stage IV, dead, 364 days	656.6
TCGA-C4-A0F7-01A	77 years, male, stage:Stage IV, dead, 62 days	649.0
TCGA-FD-A43Y-01A	65 years, male, white, stage:Stage III, dead, 474 days	642.6
TCGA-BT-A20T-01A	63 years, male, white, stage:Stage IV, dead, 453 days	633.9
TCGA-BT-A2LB-01A	73 years, female, white, stage:Stage III, dead, 492 days	633.3
TCGA-G2-A2ES-01A	85 years, male, white, stage:Stage II, dead, 1004 days	629.6
TCGA-UY-A78M-01A	81 years, female, asian, stage:Stage IV, dead, 690 days	623.6
TCGA-FD-A3B6-01A	75 years, male, white, stage:Stage II, dead, 1005 days	622.9
TCGA-FD-A5C0-01A	61 years, male, white, stage:Stage IV, dead, 550 days	618.1
TCGA-FD-A3SS-01A	66 years, male, white, stage:Stage IV, dead, 391 days	616.6
TCGA-CU-A72E-01A	76 years, male, white, stage:Stage IV, dead, 413 days	616.4
TCGA-YC-A9TC-01A	71 years, male, white, stage:Stage IV, dead, 20 days	599.8
TCGA-XF-A8HF-01A	80 years, male, white, stage:Stage III, dead, 2954 days	596.4
TCGA-DK-AA6Q-01A	61 years, female, white, stage:Stage IV, dead, 413 days	592.2
TCGA-FD-A6TG-01A	73 years, male, white, stage:Stage IV, dead, 93 days	590.4
TCGA-BT-A20N-01A	72 years, male, stage:Stage III, dead, 795 days	588.2
TCGA-DK-A2I2-01A	63 years, female, white, stage:Stage IV, dead, 237 days	588.0
TCGA-G2-A2EO-01A	69 years, male, white, stage:Stage III, dead, 1804 days	587.2
TCGA-XF-A9SX-01A	63 years, female, white, stage:Stage IV, dead, 719 days	585.3
TCGA-ZF-AA54-01A	71 years, male, white, stage:Stage III, dead, 590 days	584.6
TCGA-FJ-A3ZE-01A	65 years, male, white, stage:Stage IV, dead, 324 days	583.9
TCGA-HQ-A5ND-01A	78 years, male, stage:Stage IV, dead, 274 days	582.5
TCGA-DK-AA6W-01A	78 years, male, white, stage:Stage II, dead, 415 days	581.4
TCGA-HQ-A5NE-01A	57 years, male, stage:Stage III, dead, 370 days	579.5
TCGA-2F-A9KO-01A	63 years, male, white, stage:Stage IV, dead, 734 days	569.8
TCGA-4Z-AA7S-01A	66 years, male, black or african american, stage:Stage III, dead, 1064 days	560.5
TCGA-ZF-A9RE-01A	78 years, female, white, stage:Stage II, dead, 106 days	558.4
TCGA-DK-A1A3-01A	60 years, male, white, stage:Stage IV, dead, 665 days	556.0
TCGA-DK-A3IQ-01A	74 years, male, white, stage:Stage III, dead, 539 days	554.3
TCGA-K4-A5RI-01A	67 years, female, white, stage:Stage III, dead, 356 days	553.8
TCGA-XF-A8HI-01A	57 years, female, white, stage:Stage IV, dead, 544 days	540.7
TCGA-XF-AAMT-01A	75 years, female, white, stage:Stage IV, dead, 90 days	539.1
TCGA-GU-A42R-01A	68 years, male, white, stage:Stage IV, dead, 577 days	534.9
TCGA-G2-A2EL-01A	77 years, male, white, stage:Stage II, dead, 819 days	534.7
TCGA-ZF-AA4U-01A	70 years, male, white, stage:Stage III, dead, 262 days	533.0
TCGA-XF-A9SK-01A	65 years, male, white, stage:Stage IV, dead, 486 days	528.6
TCGA-XF-AAMH-01A	80 years, male, white, stage:Stage IV, dead, 344 days	525.4
TCGA-4Z-AA7R-01A	73 years, male, black or african american, stage:Stage IV, dead, 522 days	524.1
TCGA-DK-A3IM-01A	76 years, male, white, stage:Stage III, dead, 248 days	519.7
TCGA-K4-A4AC-01A	83 years, male, white, stage:Stage II, dead, 278 days	517.1
TCGA-XF-A9SP-01A	59 years, male, white, stage:Stage III, dead, 454 days	514.0
TCGA-BL-A13J-01A	65 years, male, white, stage:Stage IV, dead, 81 days	512.0
TCGA-DK-A2HX-01A	80 years, female, white, stage:Stage IV, dead, 1420 days	511.3
TCGA-XF-AAN1-01A	75 years, female, stage:Stage III, dead, 941 days	505.4
TCGA-ZF-AA4N-01A	74 years, male, white, stage:Stage II, dead, 88 days	503.1
TCGA-CU-A0YN-01A	60 years, male, white, stage:Stage III, dead, 393 days	502.8
TCGA-UY-A78N-01A	80 years, male, white, stage:Stage IV, dead, 2641 days	502.2
TCGA-FD-A3SR-01A	68 years, male, white, stage:Stage IV, dead, 602 days	499.1
TCGA-CF-A9FL-01A	85 years, male, asian, stage:Stage III, dead, 565 days	495.1
TCGA-BT-A20U-01A	70 years, female, white, stage:Stage III, dead, 455 days	494.0
TCGA-GC-A3I6-01A	45 years, male, white, stage:Stage III, dead, 630 days	488.1
TCGA-FD-A6TH-01A	63 years, male, white, stage:Stage IV, dead, 131 days	487.6
TCGA-FD-A5BZ-01A	77 years, female, white, stage:Stage IV, dead, 835 days	482.0
TCGA-BT-A2LD-01A	78 years, female, white, stage:Stage IV, dead, 623 days	481.7
TCGA-FJ-A3Z9-01A	72 years, male, white, stage:'--, dead, 385 days	481.2
TCGA-FD-A3SJ-01A	59 years, male, white, stage:Stage IV, dead, 739 days	478.1
TCGA-GU-A42Q-01A	67 years, male, white, stage:Stage III, dead, 344 days	476.1
TCGA-G2-A2EC-01A	58 years, female, black or african american, stage:Stage II, dead, 696 days	475.9
TCGA-4Z-AA82-01A	59 years, male, black or african american, stage:Stage IV, dead, 1556 days	473.4
TCGA-BT-A3PK-01A	80 years, male, white, stage:Stage II, dead, 303 days	472.8
TCGA-XF-AAMW-01A	79 years, female, white, stage:Stage IV, dead, 253 days	471.3
TCGA-DK-A3IK-01A	87 years, male, white, stage:Stage IV, dead, 146 days	469.9
TCGA-XF-A9SU-01A	74 years, female, white, stage:Stage IV, dead, 182 days	466.6
TCGA-DK-A3IN-01A	72 years, male, white, stage:Stage III, dead, 250 days	466.4
TCGA-BT-A20W-01A	71 years, male, white, stage:Stage II, dead, 254 days	464.4
TCGA-CU-A0YR-01A	83 years, male, white, stage:Stage IV, dead, 460 days	463.3
TCGA-BT-A0S7-01A	75 years, male, white, stage:Stage III, dead, 200 days	461.9
TCGA-XF-AAMX-01A	87 years, female, black or african american, stage:Stage III, dead, 206 days	459.8
TCGA-GU-AATQ-01A	68 years, male, white, stage:Stage III, dead, 213 days	457.2
TCGA-G2-A3IE-01A	51 years, male, white, stage:Stage II, dead, 612 days	454.9
TCGA-BT-A20V-01A	59 years, female, black or african american, stage:Stage IV, dead, 154 days	450.7
TCGA-XF-A9T8-01A	64 years, male, white, stage:Stage III, dead, 418 days	446.8
TCGA-FD-A3SL-01A	60 years, male, white, stage:Stage IV, dead, 712 days	446.2
TCGA-XF-A9T2-01A	54 years, male, white, stage:Stage III, dead, 575 days	443.4
TCGA-XF-AAML-01A	75 years, male, white, stage:Stage II, dead, 232 days	441.4
TCGA-XF-A9SV-01A	82 years, male, white, stage:Stage IV, dead, 388 days	440.3
TCGA-XF-AAN2-01A	73 years, male, white, stage:Stage II, dead, 1869 days	439.8
TCGA-CF-A47T-01A	58 years, female, asian, stage:Stage II, dead, 385 days	436.2
TCGA-FD-A6TF-01A	80 years, female, white, stage:Stage IV, dead, 69 days	435.9
TCGA-GC-A3BM-01A	70 years, male, white, stage:Stage II, dead, 651 days	435.7
TCGA-CU-A5W6-01A	70 years, male, white, stage:Stage III, dead, 56 days	431.3
TCGA-BT-A20J-01A	75 years, male, white, stage:Stage II, dead, 579 days	430.7
TCGA-2F-A9KR-01A	59 years, female, stage:Stage III, dead, 3183 days	429.3
TCGA-FD-A3SO-01A	68 years, male, white, stage:Stage IV, dead, 168 days	429.2
TCGA-4Z-AA81-01A	80 years, male, white, stage:Stage II, dead, 1270 days	425.9
TCGA-GV-A3QH-01A	67 years, male, white, stage:Stage II, dead, 258 days	421.3
TCGA-DK-A3IL-01A	79 years, female, white, stage:Stage IV, dead, 413 days	418.9
TCGA-BT-A0YX-01A	70 years, female, white, stage:Stage III, dead, 400 days	417.7
TCGA-DK-A3IU-01A	58 years, male, white, stage:Stage II, dead, 706 days	413.4
TCGA-DK-A3X2-01A	85 years, male, white, stage:Stage IV, dead, 547 days	406.7
TCGA-XF-A8HH-01A	61 years, female, white, stage:Stage IV, dead, 57 days	406.3
TCGA-FD-A62S-01A	60 years, female, black or african american, stage:Stage III, dead, 406 days	404.9
TCGA-UY-A78K-01A	60 years, male, white, stage:Stage IV, dead, 536 days	401.3
TCGA-XF-AAN4-01A	77 years, female, white, stage:Stage III, dead, 823 days	399.0
TCGA-XF-AAMJ-01A	70 years, male, asian, stage:Stage III, dead, 1670 days	390.6
TCGA-GV-A3QF-01A	79 years, male, white, stage:Stage IV, dead, 617 days	388.8
TCGA-XF-AAMZ-01A	81 years, female, white, stage:Stage IV, dead, 1348 days	377.6
TCGA-XF-AAN8-01A	74 years, female, white, stage:Stage III, dead, 118 days	377.5
TCGA-XF-A8HC-01A	79 years, male, asian, stage:Stage IV, dead, 200 days	375.5
TCGA-BT-A20Q-01A	73 years, male, white, stage:Stage IV, dead, 593 days	373.2
TCGA-G2-AA3C-01A	66 years, male, white, stage:Stage IV, dead, 211 days	369.9
TCGA-SY-A9G0-01A	82 years, male, white, stage:Stage IV, dead, 1008 days	369.1
TCGA-FD-A6TI-01A	73 years, male, white, stage:Stage IV, dead, 294 days	364.4
TCGA-ZF-A9R0-01A	82 years, male, white, stage:Stage III, dead, 680 days	362.8
TCGA-BT-A20P-01A	81 years, female, white, stage:Stage III, dead, 544 days	362.3
TCGA-5N-A9KM-01A	73 years, female, white, stage:Stage III, dead, 530 days	359.8
TCGA-BT-A20O-01A	75 years, male, white, stage:Stage III, dead, 370 days	359.4
TCGA-XF-A9SJ-01A	83 years, male, white, stage:Stage IV, dead, 98 days	357.9
TCGA-DK-AA75-01A	82 years, male, white, stage:Stage III, dead, 340 days	355.4
TCGA-ZF-A9R3-01A	53 years, female, white, stage:Stage II, dead, 949 days	341.5
TCGA-FD-A3SQ-01A	62 years, male, white, stage:Stage IV, dead, 1423 days	336.7
TCGA-FD-A62O-01A	74 years, male, white, stage:Stage IV, dead, 216 days	335.7
TCGA-CU-A0YO-01A	84 years, male, white, stage:Stage IV, dead, 149 days	335.2
TCGA-XF-A9SH-01A	65 years, female, asian, stage:Stage II, dead, 1971 days	332.2
TCGA-GU-AATO-01A	75 years, male, white, stage:Stage IV, dead, 324 days	329.9
TCGA-4Z-AA7Q-01A	79 years, male, white, stage:Stage III, dead, 510 days	327.3
TCGA-FD-A5BV-01A	47 years, female, white, stage:Stage III, dead, 163 days	324.5
TCGA-E7-A4XJ-01A	66 years, male, asian, stage:Stage II, dead, 68 days	319.7
TCGA-FD-A3B7-01A	66 years, male, black or african american, stage:Stage III, dead, 122 days	311.8
TCGA-2F-A9KW-01A	67 years, female, white, stage:Stage III, dead, 254 days	308.0
TCGA-4Z-AA7N-01A	65 years, male, white, stage:Stage III, dead, 1367 days	302.9
TCGA-XF-A9SL-01A	69 years, male, white, stage:Stage IV, dead, 2020 days	301.7
TCGA-GU-A42P-01A	72 years, male, white, stage:Stage IV, dead, 332 days	300.5
TCGA-XF-AAN0-01A	68 years, male, white, stage:Stage IV, dead, 1718 days	289.5
TCGA-E7-A541-01A	66 years, male, white, stage:Stage II, dead, 778 days	275.4
TCGA-XF-AAME-01A	64 years, female, white, stage:Stage II, dead, 2828 days	275.2
TCGA-FD-A5BT-01A	84 years, male, white, stage:Stage III, dead, 328 days	274.8
TCGA-ZF-AA4T-01A	65 years, male, white, stage:Stage IV, dead, 599 days	273.0
TCGA-ZF-AA52-01A	70 years, male, white, stage:Stage III, dead, 1077 days	268.5
TCGA-XF-A9SW-01A	85 years, male, white, stage:Stage IV, dead, 362 days	264.3
TCGA-S5-A6DX-01A	83 years, male, white, stage:Stage IV, dead, 56 days	246.9
TCGA-BL-A13I-01A	57 years, female, white, stage:Stage III, dead, 223 days	243.2
TCGA-GV-A3JV-01A	66 years, male, white, stage:Stage IV, dead, 434 days	223.2
TCGA-ZF-A9R9-01A	58 years, male, white, stage:Stage IV, dead, 864 days	154.9
TCGA-XF-A8HG-01A	69 years, male, white, stage:Stage III, dead, 467 days	90.1
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UROTHELIAL CANCER - Protein expressionⁱ

Pending cancer tissue analysis