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On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.
Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.
If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.
No data
RNA expressioni
A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.
The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.
Scroll down to view mRNA expression data in more detail.
Consensus:
2.1
nTPM
HPA Brain:
25.0
nTPM
GTEx:
2.1
nTPM
FANTOM5:
6.3
Scaled Tags Per Million
Pig:
14.4
nTPM
Mouse:
21.3
nTPM
Allen mouse:
2.1
Expression energy
MIDBRAIN - Annotated protein expression
Pending normal tissue analysis
MIDBRAIN - HPA Brain RNA-seq
Max subtype nTPMi
Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.
25.0
Sample id
Sample description
nTPM
Cuneiform nucleus nTPM: 21.2
2411
Female, age 72, unknown
23.9
2586
Male, age 75, left hemisphere
23.8
1827
Male, age 72, unknown
22.8
2019
Male, age 18, unknown
22.1
2219
Male, age 76, both hemispheres
21.8
1833
Male, age 53, unknown
20.3
1870
Female, age 42, unknown
20.3
2666
Male, age 74, left hemisphere
19.7
1830
Male, age 51, unknown
18.5
2828
Female, age 72, unknown
18.4
Dorsal raphe nucleus nTPM: 22.0
2298
Female, age 72, unknown
24.7
2016
Female, age 72, unknown
22.7
2047
Male, age 72, unknown
21.4
1828
Male, age 53, unknown
21.3
2750
Male, age 76, both hemispheres
19.7
Inferior colliculus nTPM: 23.8
2849
Male, age 72, unknown
25.2
2097
Female, age 72, unknown
24.9
1848
Female, age 42, unknown
23.3
1890
Male, age 53, unknown
22.0
Median raphe nucleus nTPM: 25.0
2220
Male, age 76, midline
25.0
Periaquaductal grey, anterior nTPM: 23.5
2502
Female, age 75, unknown
30.0
1795
Male, age 51, unknown
20.9
1947
Male, age 18, unknown
19.5
Periaquaductal grey, dorsal nTPM: 24.9
1840
Male, age 53, unknown
29.7
1831
Male, age 72, unknown
23.9
2850
Male, age 76, both hemispheres
23.6
2464
Female, age 72, unknown
22.5
Periaquaductal grey, lateral nTPM: 22.2
2140
Male, age 76, both hemispheres
25.1
2272
Male, age 74, both hemispheres
20.9
2053
Male, age 18, unknown
20.7
Pretectal area nTPM: 25.0
1944
Female, age 72, unknown
33.1
1816
Male, age 51, unknown
31.5
2007
Male, age 72, unknown
29.3
2224
Female, age 72, unknown
28.0
1817
Female, age 42, unknown
25.2
1815
Male, age 53, unknown
24.8
2273
Male, age 74, both hemispheres
24.4
2825
Male, age 18, unknown
20.8
2667
Female, age 75, unknown
20.1
2407
Male, age 75, both hemispheres
19.7
2316
Male, age 76, right hemisphere
17.7
Red nucleus nTPM: 17.0
2785
Male, age 18, unknown
23.4
2584
Male, age 75, left hemisphere
19.7
2725
Female, age 75, unknown
19.1
2588
Male, age 74, left hemisphere
18.4
2503
Female, age 72, unknown
17.4
1821
Female, age 72, unknown
16.9
2227
Male, age 72, unknown
15.7
1954
Female, age 42, unknown
15.5
1865
Male, age 51, unknown
14.9
1904
Male, age 53, unknown
14.6
2769
Male, age 72, unknown
14.6
2823
Male, age 76, right hemisphere
13.8
Substantia nigra nTPM: 22.4
1889
Female, age 72, unknown
27.1
2241
Male, age 72, unknown
25.2
1851
Male, age 51, unknown
24.5
1916
Female, age 42, unknown
24.5
2665
Male, age 74, both hemispheres
23.7
1941
Male, age 53, unknown
22.6
2699
Male, age 18, unknown
20.3
2583
Male, age 75, right hemisphere
19.0
2590
Female, age 75, unknown
18.5
2409
Female, age 72, unknown
18.2
Superior colliculus nTPM: 22.2
2087
Female, age 72, unknown
28.5
2261
Male, age 18, unknown
24.8
2664
Male, age 75, both hemispheres
23.3
1796
Male, age 53, unknown
22.2
2587
Male, age 74, left hemisphere
21.8
2668
Female, age 75, unknown
21.8
1895
Male, age 76, right hemisphere
21.6
1839
Male, age 51, unknown
21.4
1913
Female, age 42, unknown
18.5
1995
Male, age 72, unknown
18.5
Ventral tegmental area nTPM: 21.5
2218
Male, age 76, both hemispheres
26.0
2021
Male, age 53, unknown
22.7
1915
Female, age 42, unknown
22.3
1942
Male, age 51, unknown
21.7
2410
Female, age 72, unknown
20.6
2223
Female, age 72, unknown
15.5
MIDBRAIN - GTEx RNA-seqi
RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.
Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi
Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.
2.1
GTEx sample id
Sample description
nTPM
Brain - Substantia nigra Average nTPM: 2.1
Samples: 139
Max nTPM: 4.1
Min nTPM: 0.8
Std nTPM: 0.6
Median nTPM: 2.0
GTEX-N7MS-0011-R2a-SM-2HML6
60-69 years, male
4.1
GTEX-13PDP-0011-R2b-SM-5O9DH
60-69 years, male
3.7
GTEX-15ER7-0011-R2a-SM-6M46O
20-29 years, female
3.6
GTEX-Z93S-0011-R2a-SM-4RGNG
50-59 years, male
3.6
GTEX-XMD1-0011-R2B-SM-4AT5N
60-69 years, male
3.4
GTEX-1313W-0011-R2a-SM-5EGLF
50-59 years, female
3.3
GTEX-OXRO-0011-R2A-SM-3NB1W
60-69 years, female
3.3
GTEX-Q2AG-0011-R2A-SM-2HMIT
40-49 years, female
3.2
GTEX-1HFI6-0011-R2a-SM-CMKH5
40-49 years, male
3.1
GTEX-15EO6-0011-R2a-SM-6M46R
50-59 years, male
2.9
GTEX-NPJ8-0011-R2a-SM-2TC6M
40-49 years, male
2.9
GTEX-QDT8-0011-R2A-SM-32PKQ
30-39 years, female
2.9
GTEX-WHSE-0011-R2A-SM-3P5ZL
20-29 years, male
2.9
GTEX-1H1ZS-0011-R2b-SM-CL54Q
70-79 years, male
2.9
GTEX-1HB9E-0011-R2b-SM-A96RW
50-59 years, male
2.9
GTEX-1HT8W-0011-R2a-SM-CMKH9
30-39 years, male
2.9
GTEX-1LVAO-0011-R2a-SM-EYYX1
60-69 years, male
2.9
GTEX-12ZZX-0011-R2a-SM-5EGLG
40-49 years, female
2.8
GTEX-13NYB-0011-R2a-SM-5MR3C
40-49 years, male
2.8
GTEX-13NYS-0011-R2b-SM-5MR4G
60-69 years, male
2.8
GTEX-1B933-0011-R2b-SM-7IGNM
50-59 years, female
2.8
GTEX-1IL2U-0011-R2a-SM-ARU6V
60-69 years, male
2.8
GTEX-13CF2-0011-R2a-SM-5L3DC
60-69 years, male
2.7
GTEX-13OVJ-0011-R2b-SM-5L3GP
50-59 years, female
2.7
GTEX-15CHQ-0011-R2b-SM-6AJAD
60-69 years, male
2.7
GTEX-T5JC-0011-R2A-SM-32PLZ
20-29 years, male
2.7
GTEX-ZAB4-0011-R2a-SM-4RGNP
40-49 years, male
2.7
GTEX-11DZ1-0011-R2a-SM-DNZZM
50-59 years, male
2.7
GTEX-1GN73-0011-R2a-SM-CJI2V
60-69 years, male
2.7
GTEX-13SLX-0011-R2b-SM-5S2VP
50-59 years, female
2.6
GTEX-1H3VE-0011-R2a-SM-CE6SA
40-49 years, male
2.6
GTEX-1I1GV-0011-R2a-SM-ARZLF
60-69 years, male
2.6
GTEX-11UD1-0011-R2b-SM-5BC6O
40-49 years, female
2.5
GTEX-13X6K-0011-R2b-SM-5P9K3
60-69 years, female
2.5
GTEX-14C5O-0011-R2a-SM-5ZZV2
60-69 years, male
2.5
GTEX-YFC4-0011-R2a-SM-4V6DZ
40-49 years, female
2.5
GTEX-1GN2E-0011-R2a-SM-9WG7D
60-69 years, male
2.5
GTEX-13OW6-0011-R2a-SM-5L3HG
50-59 years, male
2.4
GTEX-13X6I-0011-R2b-SM-5PNWQ
60-69 years, male
2.4
GTEX-1A8G7-0011-R2a-SM-7IGQI
60-69 years, male
2.4
GTEX-NPJ7-0011-R2a-SM-2I3GF
60-69 years, female
2.4
GTEX-1EMGI-0011-R2b-SM-9OSVS
60-69 years, male
2.4
GTEX-1H23P-0011-R2a-SM-CKZP3
60-69 years, male
2.4
GTEX-12WSF-0011-R2a-SM-5DUVU
70-79 years, male
2.3
GTEX-12WSH-0011-R2a-SM-5GU68
50-59 years, male
2.3
GTEX-13O3Q-0011-R2b-SM-5KM3K
50-59 years, male
2.3
GTEX-145LS-0011-R2a-SM-5PNZI
60-69 years, female
2.3
GTEX-1B996-0011-R2a-SM-7IGON
60-69 years, male
2.3
GTEX-1B8L1-0011-R2a-SM-9OSVL
60-69 years, male
2.3
GTEX-1HSMO-0011-R2a-SM-CL553
60-69 years, male
2.3
GTEX-1399T-0011-R2b-SM-5DUXM
60-69 years, male
2.2
GTEX-13RTJ-0011-R2a-SM-5PNW9
60-69 years, male
2.2
GTEX-14PJO-0011-R2a-SM-5ZZVF
60-69 years, male
2.2
GTEX-1B8SG-0011-R2b-SM-79OOT
50-59 years, male
2.2
GTEX-T2IS-0011-R2A-SM-32QPF
20-29 years, female
2.2
GTEX-11GSP-0011-R2b-SM-9QEGE
60-69 years, female
2.2
GTEX-1F75B-0011-R2a-SM-ARL8I
50-59 years, male
2.2
GTEX-1GZ2Q-0011-R2b-SM-9OSWO
40-49 years, male
2.2
GTEX-1LSNL-0011-R2a-SM-EZ6MK
50-59 years, male
2.2
GTEX-1445S-0011-R2b-SM-5PNUH
60-69 years, male
2.1
GTEX-P44G-0011-R2A-SM-2XCD2
30-39 years, male
2.1
GTEX-X4XX-0011-R2A-SM-3P623
60-69 years, male
2.1
GTEX-ZV68-0011-R2a-SM-4YCDK
50-59 years, female
2.1
GTEX-1C6VR-0011-R2a-SM-7RHGZ
60-69 years, male
2.1
GTEX-1EKGG-0011-R2a-SM-CE6R8
60-69 years, male
2.1
GTEX-1IGQW-0011-R2b-SM-D4P26
60-69 years, male
2.1
GTEX-132Q8-0011-R2b-SM-5EQ5Z
60-69 years, male
2.0
GTEX-1A3MX-0011-R2b-SM-7EWFL
60-69 years, male
2.0
GTEX-NL4W-0011-R2a-SM-2I5GV
50-59 years, male
2.0
GTEX-PWO3-0011-R2A-SM-2S1OX
60-69 years, female
2.0
GTEX-RU72-0011-R2A-SM-2TF6O
50-59 years, female
2.0
GTEX-11EMC-0011-R2b-SM-DO114
60-69 years, female
2.0
GTEX-11ZTS-0011-R2b-SM-5BC75
60-69 years, female
1.9
GTEX-14BIM-0011-R2b-SM-69LQ6
60-69 years, female
1.9
GTEX-18464-0011-R2a-SM-731AL
50-59 years, male
1.9
GTEX-1CB4G-0011-R2a-SM-9QEGQ
60-69 years, male
1.9
GTEX-1E1VI-0011-R2a-SM-9QEGS
50-59 years, male
1.9
GTEX-11GSO-0011-R2a-SM-57WDF
60-69 years, male
1.8
GTEX-13N2G-0011-R2a-SM-5MR4Q
60-69 years, male
1.8
GTEX-13SLW-0011-R2b-SM-5O9C6
70-79 years, male
1.8
GTEX-14ASI-0011-R2b-SM-5YY9H
60-69 years, male
1.8
GTEX-14JG1-0011-R2a-SM-5ZZVE
40-49 years, male
1.8
GTEX-OHPN-0011-R2A-SM-2I5FB
60-69 years, female
1.8
GTEX-QMR6-0011-R2A-SM-32PKV
50-59 years, male
1.8
GTEX-UTHO-0011-R2A-SM-3GIKC
60-69 years, male
1.8
GTEX-XLM4-0011-R2B-SM-4AT5Z
60-69 years, male
1.8
GTEX-1F6IF-0011-R2b-SM-9QEHB
60-69 years, male
1.8
GTEX-1GN1U-0011-R2a-SM-CL53A
50-59 years, female
1.8
GTEX-1HR98-0011-R2a-SM-ARL7A
60-69 years, male
1.8
GTEX-1LVA9-0011-R2a-SM-EZ6MJ
50-59 years, male
1.8
GTEX-11PRG-0011-R2a-SM-69LQ5
50-59 years, male
1.7
GTEX-131XH-0011-R2b-SM-5DUVY
50-59 years, male
1.7
GTEX-13QJC-0011-R2b-SM-5PNUN
60-69 years, female
1.7
GTEX-15DCD-0011-R2b-SM-6LPIE
70-79 years, female
1.7
GTEX-16Z82-0011-R2b-SM-79OK9
60-69 years, male
1.7
GTEX-X585-0011-R2B-SM-46MVF
50-59 years, male
1.7
GTEX-11WQC-0011-R2a-SM-DO927
60-69 years, male
1.7
GTEX-1F6I4-0011-R2a-SM-CL536
60-69 years, male
1.7
GTEX-1GMR8-0011-R2a-SM-CE6RD
50-59 years, female
1.7
GTEX-1GTWX-0011-R2b-SM-ADEH5
60-69 years, male
1.7
GTEX-1H3O1-0011-R2b-SM-CKZOT
60-69 years, male
1.7
GTEX-1J1OQ-0011-R2b-SM-ARU88
40-49 years, female
1.7
GTEX-1J8Q2-0011-R2b-SM-EAZ2X
60-69 years, male
1.7
GTEX-1JMQK-0011-R2a-SM-EYYXQ
60-69 years, male
1.7
GTEX-YJ89-0011-R2b-SM-4RGLT
60-69 years, male
1.6
GTEX-ZE9C-0011-R2a-SM-4WKGH
60-69 years, male
1.6
GTEX-11TUW-0011-R2b-SM-DO92T
60-69 years, male
1.6
GTEX-1EU9M-0011-R2b-SM-9QEH7
60-69 years, male
1.6
GTEX-1IKJJ-0011-R2b-SM-ARZLJ
60-69 years, male
1.6
GTEX-1LH75-0011-R2b-SM-EYYWQ
50-59 years, female
1.6
GTEX-13G51-0011-R2b-SM-5LZXS
60-69 years, male
1.5
GTEX-147GR-0011-R2b-SM-5S2RQ
60-69 years, male
1.5
GTEX-17EVP-0011-R2a-SM-7LG4W
40-49 years, male
1.5
GTEX-T6MN-0011-R2A-SM-32QOW
50-59 years, male
1.5
GTEX-1I1CD-0011-R2a-SM-CM2T3
60-69 years, female
1.5
GTEX-12WSA-0011-R2a-SM-57WDK
60-69 years, male
1.4
GTEX-139TS-0011-R2b-SM-5J1MX
60-69 years, male
1.4
GTEX-14PN4-0011-R2a-SM-6EU2Y
50-59 years, male
1.4
GTEX-15DYW-0011-R2b-SM-7KUKY
60-69 years, female
1.4
GTEX-N7MT-0011-R2a-SM-2I3GI
60-69 years, female
1.4
GTEX-1IY9M-0011-R2a-SM-D4P29
60-69 years, male
1.4
GTEX-R55E-0011-R2A-SM-EYYV9
20-29 years, male
1.4
GTEX-13FXS-0011-R2b-SM-5K7XX
50-59 years, male
1.3
GTEX-13O3O-0011-R2b-SM-5P9H1
60-69 years, female
1.3
GTEX-14BIN-0011-R2a-SM-5S2RJ
50-59 years, female
1.3
GTEX-17HG3-0011-R2a-SM-7MGVX
30-39 years, female
1.3
GTEX-1H1DG-0011-R2a-SM-ADEIQ
70-79 years, male
1.3
GTEX-1I1GS-0011-R2b-SM-CMKHG
60-69 years, male
1.3
GTEX-1MA7X-0011-R2b-SM-EZ6MT
60-69 years, male
1.3
GTEX-12WSD-0011-R2a-SM-5LZWB
60-69 years, female
1.2
GTEX-13OW8-0011-R2a-SM-5L3G2
60-69 years, male
1.2
GTEX-15RJE-0011-R2b-SM-79OMP
40-49 years, male
1.2
GTEX-1RLM8-0011-R2a-SM-EZ6N4
50-59 years, male
1.2
GTEX-1F48J-0011-R2a-SM-CL535
50-59 years, female
1.1
GTEX-S7SE-0011-R2A-SM-2XCDC
50-59 years, male
1.0
GTEX-11GS4-0011-R2a-SM-DO942
60-69 years, male
1.0
GTEX-1IKOH-0011-R2a-SM-CMKHO
60-69 years, female
1.0
GTEX-1LB8K-0011-R2a-SM-EZ6MQ
50-59 years, male
0.9
GTEX-ZDXO-0011-R2b-SM-4WKFG
60-69 years, male
0.8
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MIDBRAIN - FANTOM5 CAGEi
RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.
Max subtype Scaled Tags Per Millioni
Max subtype Scaled Tags Per Million is the value for the subtype with the largest average Scaled Tags Per Million across the subtype samples.
Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi
Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.
Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi
Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.
21.3
Mouse sample
Sample description
nTPM
Midbrain nTPM: 21.3
Samples: 4
Max nTPM: 22.2
Min nTPM: 20.4
Sample A
Male
20.4
Sample B
Male
22.1
Sample C
Female
22.2
Sample D
Female
20.5
MIDBRAIN - Allen Mouse ISHi
In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.
Max subtype Expression energyi
Max subtype Expression energy is the value for the subtype with the largest average Expression energy across the subtype samples.