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The primary data page shows the detailed antibody staining in 76 different cell types for each analyzed antibody. In addition, for each cell type, a knowledge-based annotated protein expression score based on all analyzed antibodies is displayed furthest to the right. The images and annotations can be accessed by clicking on the tissue name or score bar. More information can be found in Assays & Annotation.
The tissues and cell types can be ordered by organ, cell type or alphabetically. If ordered by organ, the tissues are presented in groups according to functional features. If ordered by cell type, the cells are presented in groups related to origin.
This score describes the level of antibody staining observed in the annotated cell types as not detected (n), low (l), medium (m) or high (h). It is based on the staining intensity and fraction of stained cells. The images and annotations can be accessed by clicking on the tissue name or score bar. More information can be found in Assays & Annotation.
Annotated protein expressioni
This score describes a knowledge-based best estimate of the protein expression in the annotated cell types as not detected (n), low (l), medium (m) or high (h). It is a result of stringent evaluation of immunohistochemical staining pattern, RNA data from internal and external sources and available protein/gene characterization data. More information can be found in Assays & Annotation.
Summarizing texts describe the staining pattern for each antibody based on staining intensity, fraction of stained cells and subcellular localization. More information can be found in Assays & Annotation.
HPA003394
Red blood cells showed specific and strong cytoplasmic and membranous staining. Epididymis, islet cells of pancreas, heart muscle, cells of the granular layer in cerebellum and subsets of cells in bone marrow showed moderate to strong membranous staining. Neuronal cells in CNS showed cytoplasmic positivity. Remaining normal tissues were generally negative.
HPA003398
Red blood cells showed specific and strong cytoplasmic and membranous staining. Moderate to strong membranous positivity was observed heart muscle, islets of pancreas, epidydimis, cells of the granular layer in cerebellum and subsets of cells in bone marrow. Neuronal cells in CNS showed cytoplasmic positivity. Remaining normal tissues were weakly stained or negative.
CAB015169
Most normal tissues displayed weak to moderate cytoplasmic and membranous positivity. Distinct positivity was observed in erythrocytes, parathyroid gland, epididymis and in the granular layer of cerebellum.
CAB016232
Strong cytoplasmic positivity was displayed in erythrocytes, subset of hematopoietic cells and granular layer of cerebellum. Neuronal cells, renal glomeruli and smooth muscle cells were weak to moderately stained. Epididymis showed strong membranous staining. Skeletal and heart myocytes exhibited moderate membranous immunoreactivity. Remaining normal tissues were negative.
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