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The primary data page shows the detailed antibody staining in 76 different cell types for each analyzed antibody. In addition, for each cell type, a knowledge-based annotated protein expression score based on all analyzed antibodies is displayed furthest to the right. The images and annotations can be accessed by clicking on the tissue name or score bar. More information can be found in Assays & Annotation.
The tissues and cell types can be ordered by organ, cell type or alphabetically. If ordered by organ, the tissues are presented in groups according to functional features. If ordered by cell type, the cells are presented in groups related to origin.
This score describes the level of antibody staining observed in the annotated cell types as not detected (n), low (l), medium (m) or high (h). It is based on the staining intensity and fraction of stained cells. The images and annotations can be accessed by clicking on the tissue name or score bar. More information can be found in Assays & Annotation.
Annotated protein expressioni
This score describes a knowledge-based best estimate of the protein expression in the annotated cell types as not detected (n), low (l), medium (m) or high (h). It is a result of stringent evaluation of immunohistochemical staining pattern, RNA data from internal and external sources and available protein/gene characterization data. More information can be found in Assays & Annotation.
Summarizing texts describe the staining pattern for each antibody based on staining intensity, fraction of stained cells and subcellular localization. More information can be found in Assays & Annotation.
HPA045396
Normal tissues displayed moderate to strong cytoplasmic staining with additional membranous positivity in few tissues. Nuclear staining was observed in neuronal cells, oral mucosa, decidual cells and squamous epithelia.
HPA070524
Strong cytoplasmic postivity was observed in intestinal glandular cells and a subset of glial cells. Weak to moderate staining was displayed in several other tissues, including testis, kidney and endometrium.
CAB025331
Most normal tissues showed moderate cytoplasmic staining often combined with membranous immunoreactivity. Strong immunoreactivity was for example observed in gastric parietal cells, renal tubuli, placental trophoblasts and astrocytes.