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                                        PROTEIN SUMMARY GENE INFORMATION RNA DATA ANTIBODY DATA
                                        RNA SUMMARY - Normalized
                                        Tissue consensus dataseti

                                        The consensus dataset consists of normalized expression (nTPM) levels for 55 tissue types, created by combining the HPA and GTEx transcriptomics datasets using the internal normalization pipeline. Color-coding is based on tissue groups, each consisting of tissues with functional features in common. To access sample data, click on tissue name or bar.

                                        Read more about how the datasets were combined into consensus normalized expression levels in Assays & annotation.

                                        Cerebral cortexCerebellumBasal gangliaHypothalamusMidbrainAmygdalaChoroid plexusHippocampal formationSpinal cordRetinaThyroid glandParathyroid glandAdrenal glandPituitary glandLungSalivary glandEsophagusTongueStomachDuodenumSmall intestineColonRectumLiverGallbladderPancreasKidneyUrinary bladderTestisEpididymisSeminal vesicleProstateVaginaOvaryFallopian tubeEndometriumCervixPlacentaBreastHeart muscleSmooth muscleSkeletal muscleAdipose tissueSkinAppendixSpleenLymph nodeTonsilBone marrowThymus020406080100120nTPM
                                        Single cell typei

                                        A summary of normalized single cell RNA (nTPM) from all single cell types. Color-coding is based on cell type groups, each consisting of cell types with functional features in common.

                                        Ciliated cellsBasal respiratory cellsClub cellsIonocytesMucus glandular cellsSerous glandular cellsGastric mucus-secreting cellsProximal enterocytesPaneth cellsDistal enterocytesIntestinal goblet cellsExocrine glandular cellsBasal prostatic cellsProstatic glandular cellsBreast glandular cellsBreast myoepithelial cellsGlandular and luminal cellsSecretory cellsBasal keratinocytesSuprabasal keratinocytesBasal squamous epithelial cellsSquamous epithelial cellsAlveolar cells type 1Alveolar cells type 2Salivary duct cellsDuctal cellsHepatocytesCholangiocytesProximal tubular cellsDistal tubular cellsCollecting duct cellsMesothelial cellsSertoli cellsGranulosa cellsEnteroendocrine cellsPancreatic endocrine cellsLeydig cellsExcitatory neuronsInhibitory neuronsCone photoreceptor cellsRod photoreceptor cellsBipolar cellsHorizontal cellsAstrocytesOligodendrocyte precursor cellsOligodendrocytesMicroglial cellsMuller glia cellsSchwann cellsSpermatogoniaSpermatocytesEarly spermatidsLate spermatidsOocytesCytotrophoblastsSyncytiotrophoblastsExtravillous trophoblastsEndothelial cellsLymphatic endothelial cellsCardiomyocytesSkeletal myocytesSmooth muscle cellsAdipocytesMelanocytesFibroblastsPeritubular cellsEndometrial stromal cellsOvarian stromal cellsUndifferentiated cellsT-cellsB-cellsPlasma cellsNk-cellsGranulocytesMonocytesMacrophagesHofbauer cellsKupffer cellsDendritic cellsLangerhans cellsErythroid cells0100200300400500nTPM
                                        Brain regional consensus dataseti

                                        Consensus normalized expression (nTPM) levels were created for the 13 brain regions based on the HPA brain transcriptomics dataset. Color-coding is based on the brain region, in several cases consisting of the highest expression among the subregions included. To access sample data, click on region name or bar.

                                        Read more about normalization of transcriptomics data in<a href="/about/assays+annotation#normalization_rna"_blank">Assays & Annotation.

                                        Cerebral cortexHippocampal formationAmygdalaBasal gangliaThalamusHypothalamusMidbrainCerebellumPonsMedulla oblongataSpinal cordWhite matterChoroid plexus05101520nTPM
                                        HPA immune cell dataseti

                                        The resulting transcript expression values calculated as nTPM, resulting from the internal normalization pipeline for 18 immune cell types and total peripheral blood mononuclear cells (PBMC).

                                        BasophilEosinophilNeutrophilClassical monocyteNon-classical monocyteIntermediate monocyteT-regGdT-cellMAIT T-cellMemory CD4 T-cellNaive CD4 T-cellMemory CD8 T-cellNaive CD8 T-cellMemory B-cellNaive B-cellPlasmacytoid DCMyeloid DCNK-cellTotal PBMC05101520253035nTPM
                                        HPA cell linesi

                                        The cell lines in the Human Protein Atlas have been analyzed by RNA-seq to estimate the transcript abundance of each protein-coding gene. The RNA-seq data was then used to classify all genes according to their cell line-specific expression into one of six different categories, defined based on the total set of all nTPM values in all analyzed cell lines.

                                        Brain cancerNeuroblastomaAdrenocortical cancerThyroid cancerLung cancerEsophageal cancerHead and neck cancerColorectal cancerGastric cancerBile duct cancerGallbladder cancerLiver cancerPancreatic cancerBladder cancerKidney cancerProstate cancerTestis cancerBreast cancerCervical cancerOvarian cancerUterine cancerBone cancerRhabdoidSarcomaSkin cancerLeukemiaLymphomaMyelomaNon-cancerousUncategorized050100150200nTPM

                                        RNA SAMPLE SUMMARYi

                                        The RNA summary section shows normal distribution of individual samples across the datasets of multiple RNA-seq analyses visualized with box plots shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range.

                                        Hold mouse pointer over tissue/cell type/cell line to see sample numbers. Click on the cancer type to see cancer type sample information.

                                        HPA tissue dataset
                                        0.010.020.030.040.050.060.070.080.090.0100.0nTPMAdipose tissueAdrenal glandAppendixBone marrowBreastCerebral cortexCervixChoroid plexusColonDuodenumEndometriumEpididymisEsophagusFallopian tubeGallbladderHeart muscleKidneyLiverLungLymph nodeOvaryPancreasParathyroid glandPlacentaProstateRectumSalivary glandSeminal vesicleSkeletal muscleSkinSmall intestineSmooth muscleSpleenStomachTestisThymusThyroid glandTongueTonsilUrinary bladder
                                        GTEx tissue dataset
                                        0.050.0100.0150.0200.0250.0300.0350.0400.0450.0nTPMAdipose tissueAdrenal glandUrinary bladderAmygdalaCerebral cortexCaudateCerebellumHippocampusHypothalamusNucleus accumbensPutamenSpinal cordSubstantia nigraBreastCervixColonEsophagusFallopian tubeHeart muscleKidneyLiverLungSalivary glandSkeletal muscleOvaryPancreasPituitary glandProstateRetinaSkinSmall intestineSpleenStomachTestisThyroid glandEndometriumVagina
                                        FANTOM5 tissue dataset
                                        0.05.010.015.020.025.030.035.040.045.050.055.060.065.0Scaled Tags Per MillionAdipose tissueAmygdalaAppendixUrinary bladderBreastCaudateCerebellumCervixColonCorpus callosumDuctus deferensEpididymisEsophagusFrontal lobeGallbladderGlobus pallidusHeart muscleHippocampusInsular cortexKidneyLiverLocus coeruleusLungLymph nodeMedial frontal gyrusMedial temporal gyrusMedulla oblongataNucleus accumbensOccipital cortexOccipital lobeOccipital poleOlfactory bulbOvaryPancreasParacentral gyrusParietal lobeSalivary glandPituitary glandPlacentaPonsPostcentral gyrusProstatePutamenRetinaSeminal vesicleSkeletal muscleSmall intestineSmooth muscleSpinal cordSpleenSubstantia nigraTemporal cortexTestisThalamusThymusThyroid glandTongueTonsilEndometriumVagina
                                        HPA immune cell dataset
                                        0.05.010.015.020.025.030.035.040.0nTPMBasophilClassical monocyteEosinophilGdT-cellIntermediate monocyteMAIT T-cellMemory B-cellMemory CD4 T-cellMemory CD8 T-cellMyeloid DCNaive B-cellNaive CD4 T-cellNaive CD8 T-cellNeutrophilNK-cellNon-classical monocytePlasmacytoid DCT-regTotal PBMC
                                        Monaco immune cell dataset
                                        0.010.020.030.040.050.060.070.080.0nTPMCentral memory CD8 T-cellClassical monocyteEffector memory CD8 T-cellExhausted memory B-cellMemory CD4 T-cell TFHIntermediate monocyteBasophilNeutrophilMAIT T-cellMyeloid DCNaive B-cellNaive CD4 T-cellNaive CD8 T-cellNK-cellNon-classical monocyteNon-switched memory B-cellNon-Vd2 gdTCRTotal PBMCPlasmablastPlasmacytoid DCProgenitor cellSwitched memory B-cellT-regTerminal effector memory CD4 T-cellTerminal effector memory CD8 T-cellMemory CD4 T-cell Th1Memory CD4 T-cell Th1/Th17Memory CD4 T-cell Th17Memory CD4 T-cell Th2Vd2 gdTCR
                                        Schmiedel immune cell dataset
                                        0.05.010.015.020.025.030.035.0TPMNaive B-cellNaive CD4 T-cellNaive CD4 T-cell activatedNaive CD8 T-cellNaive CD8 T-cell activatedNon-classical monocyteClassical monocyteNK-cellMemory CD4 T-cell TFHMemory CD4 T-cell Th1Memory CD4 T-cell Th17Memory CD4 T-cell Th2Memory CD4 T-cell Th1/Th17Memory T-regNaive T-reg
                                        Pig brain dataset
                                        0.02.04.06.08.010.012.014.016.018.020.022.024.026.028.0nTPMAmygdalaCaudateCerebellumCingulate cortexCorpus callosumDorsal hippocampus Dorsal spinal cordEntorhinal cortexHypothalamusInsular cortexMedulla oblongataMidbrainMotor cortexOccipital cortexOlfactory bulbPeriaqueductal grayPituitary glandPonsPrefrontal cortexPutamenRetinaRetrosplenial cortexSeptumSomatosensory cortexSubiculumSubstantia nigraSuperior colliculiTemporal cortexThalamusVentral hippocampus Ventral pallidumVentral spinal cord
                                        Mouse brain dataset
                                        0.00.51.01.52.02.53.03.54.04.55.0nTPMAmygdalaCaudate putamenCerebellumCorpus callosumEntorhinal cortexFrontal cortexHippocampal formationHypothalamusMidbrainOccipital cortexOlfactory bulbPituitary glandPons and medullaRetinaRetrosplenial and cingulate cortexSeptumSomatosensory cortexThalamusVentral forebrain
                                        Allen mouse brain dataset
                                        0.00.10.10.10.20.30.30.30.4Expression energyCerebellumPonsOlfactory bulbHypothalamusThalamusHippocampal formationMidbrainMedulla oblongataStriatumCortical subplatePallidum
                                        Cell line dataset
                                        0.020.040.060.080.0100.0120.0140.0160.0180.0200.0220.0240.0nTPMA-431A-549AF22ASC52teloBJ [Human fibroblast]CACO-2EFO-21FHDF/TERT166GAMGHaCaTHAP1HBEC3-KTHBF/TERT88HDLM-2HEK293HELHeLaHep-G2HTCEpiHTEC/SVTERT24-BHTERT-HME1HTERT-RPE1HUVEC/TERT2JURKATK-562LHCN-M2MCF-7NB4OE19PC-3PODO/SVTERT152PODO/TERT256REHRh30RPTEC/TERT1RT-4SH-SY5YSiHaSK-MEL-30SuSaTHP-1U-251MGU2OS
                                        TCGA dataset
                                        0.050.0100.0150.0200.0250.0300.0350.0400.0450.0500.0550.0600.0650.0FPKMGlioblastoma Multiforme (TCGA)Glioblastoma Multiforme (validation)Thyroid Carcinoma (TCGA)Lung AC (TCGA)Lung AC (validation)Lung SQCC (TCGA)Lung SQCC (validation)Colon AC (TCGA)Colon AC (validation)Head and Neck SQCC (TCGA)Rectum AC (TCGA)Rectum AC (validation)Stomach AC (TCGA)Liver Hepatocellular Carcinoma (TCGA)Liver Hepatocellular Carcinoma (validation)Pancreatic AC (TCGA)Pancreatic AC (validation)Bladder Urothelial Carcinoma (TCGA)Kidney Chromophobe (TCGA)Kidney Renal Clear Cell Carcinoma (TCGA)Kidney Renal Clear Cell Carcinoma (validation)Kidney Renal Papillary Cell Carcinoma (TCGA)Prostate AC (TCGA)Testicular Germ Cell Tumor (TCGA)Breast Invasive Carcinoma (TCGA)Breast Invasive Carcinoma (validation)Cervical SQCC and Endocervical AC (TCGA)Ovary Serous Cystadenocarcinoma (TCGA)Ovary Serous Cystadenocarcinoma (validation)Uterine Corpus Endometrial Carcinoma (TCGA)Skin Cuteneous Melanoma (TCGA)

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