Metabolic pathways
The Metabolic maps enables exploration of protein function and tissue-specific gene expression in the context of the most curated human metabolic network. For proteins involved in metabolism, a metabolic summary is provided that describes the metabolic subsystems/pathways, cellular compartments, and number of reactions associated with the protein. Over 120 manually curated metabolic pathway maps facilitate the visualization of each protein's participation in different metabolic processes. Each pathway map is accompanied by a heatmap detailing the mRNA levels across 36 different tissue types for all proteins involved in the metabolic pathway.
More information about the human metabolic network, including how it was generated and what information it provides, can be found in the Methods summary.
Maps are organized by individual pathways to facilitate visualization of metabolic areas of interest. Further details and full cellular compartment maps are available at metabolicatlas.org.
An interactive pathway explorer and more information about the spatial organization of metabolism and variation on subcellular level can be found here.
Metabolic subsystem
Pentose phosphate pathway
RBKS
Cellular compartment
Table 1. A complete list of the pathways details in the Metabolic Atlas and number of enzymes involved in each pathway.
Metabolic Atlas
The metabolic features of the Metabolic Section are provided by metabolicatlas.org, which offers further detailed biochemical information on over 13,000 reactions, 8,000 metabolites, and 3,000 enzymes involved in human metabolism. Interactive 2D and 3D maps of the metabolic network are provided, and are organized by cellular compartment or metabolic subsystem to facilitate visualization of metabolic areas of interest. A global search functionality enables advanced filtering, and the same data is available through the API.
The Human Protein Atlas project is funded
