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Acute coronary syndrome Acute coronary syndrome (ACS) encompasses acute myocardial infarction (AMI) and unstable angina (UA). ACS is usually initiated by an atherosclerotic plaque rupture or disruption of the overlying endothelial surface. Subsequent thrombus formation can permanently occlude the lumen of a coronary artery, causing myocardial infarction (MI) and myocardial cell death. However, in other cases, it can be transient, or only partially occlude the vessel, resulting in UA. Risk factors include smoking, hypercholesterolemia, diabetes and hypertension (Bugiardini R et al. (2024)). In 2020, ACS-related deaths accounted for 0.04 and 0.05 per 100,000 people globally among women and men (Timmis A et al. (2023)). Acute coronary syndrome
Disease vs Healthy
Disease vs Class
Disease vs All other
Figure 1: In the volcano plot, proteins are plotted based on their fold change (logFC) on the x-axis and the statistical significance of the change (-log10 adjusted p-value) on the y-axis. Proteins considered differentially abundant are highlighted, defined by an adjusted p-value < 0.05 and an absolute logFC > 0.5.
Table 1: The summary table lists the results for all comparisons, sorted by p-value by default. It includes key metrics such as fold change and adjusted p-value, to allow exploration of the most significant proteins for each comparison.
Figure 1: In the volcano plot, proteins are plotted based on their fold change (logFC) on the x-axis and the statistical significance of the change (-log10 adjusted p-value) on the y-axis. Proteins considered differentially abundant are highlighted, defined by an adjusted p-value < 0.05 and an absolute logFC > 0.5.
Table 1: The summary table lists the results for all comparisons, sorted by p-value by default. It includes key metrics such as fold change and adjusted p-value, to allow exploration of the most significant proteins for each comparison.
Figure 1: In the volcano plot, proteins are plotted based on their fold change (logFC) on the x-axis and the statistical significance of the change (-log10 adjusted p-value) on the y-axis. Proteins considered differentially abundant are highlighted, defined by an adjusted p-value < 0.05 and an absolute logFC > 0.5.
Table 1: The summary table lists the results for all comparisons, sorted by p-value by default. It includes key metrics such as fold change and adjusted p-value, to allow exploration of the most significant proteins for each comparison.
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Contact
The Project
The Human Protein Atlas
The Human Protein Atlas project is funded
