The interactions of a protein can give valuable clues about its functions and locations. The Interaction section displays data for protein-protein as well as metabolic interaction networks. The protein-protein interaction networks displayed are extendable and interactive and can be integrated with other data to highlight proteins according to custom made filters or pre-selected features such as subcellular location or tissue specificity. The metabolic maps enables exploration of protein function and tissue-specific gene expression in the context of the human metabolic network while the metabolic summary describes the metabolic subsystems/pathways, cellular compartments, and number of reactions associated with each protein.

Key publications

• Orchard S et al., The MIntAct project--IntAct as a common curation platform for 11 molecular interaction databases. Nucleic Acids Res. (2014)
  PubMed: 24234451 DOI: 10.1093/nar/gkt1115
• Robinson JL et al., An atlas of human metabolism. Sci Signal. (2020)
  PubMed: 32209698 DOI: 10.1126/scisignal.aaz1482