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The primary data page shows the detailed antibody staining in 76 different cell types for each analyzed antibody. In addition, for each cell type, a knowledge-based annotated protein expression score based on all analyzed antibodies is displayed furthest to the right. The images and annotations can be accessed by clicking on the tissue name or score bar. More information can be found in Assays & Annotation.
The tissues and cell types can be ordered by organ, cell type or alphabetically. If ordered by organ, the tissues are presented in groups according to functional features. If ordered by cell type, the cells are presented in groups related to origin.
This score describes the level of antibody staining observed in the annotated cell types as not detected (n), low (l), medium (m) or high (h). It is based on the staining intensity and fraction of stained cells. The images and annotations can be accessed by clicking on the tissue name or score bar. More information can be found in Assays & Annotation.
Annotated protein expressioni
This score describes a knowledge-based best estimate of the protein expression in the annotated cell types as not detected (n), low (l), medium (m) or high (h). It is a result of stringent evaluation of immunohistochemical staining pattern, RNA data from internal and external sources and available protein/gene characterization data. More information can be found in Assays & Annotation.
Summarizing texts describe the staining pattern for each antibody based on staining intensity, fraction of stained cells and subcellular localization. More information can be found in Assays & Annotation.
HPA018237
Hepatocytes and Leydig cells showed strong cytoplasmic staining. Purkinje cells and prostate displayed moderate positivity. Neuronal cells of cerebral cortex, rectum and urothelial cells exhibited moderate nuclear staining. A subset of cells in seminiferus ducts displayed strong cytoplasmic and nuclear staining. Remaining normal tissues were weakly stained or negative.
HPA018287
Most normal tissues displayed moderate cytoplasmic and/or membranous positivity. Strong staining was observed in gall bladder, renal tubules and seminal vesicle. Pancreatic islets, placental trophoblasts, neuronal cells, spleen and myocytes were weakly stained or negative.
HPA018455
Hepatocytes and islets of Langerhans displayed strong cytoplasmic staining. Moderate positivity was observed in gastro-intestinal glands, gall bladder, exocrine glandular cells, decidual cells, testis and thyroid with additional membranous staining in renal tubules. Remaining normal tissues were weakly stained or negative.
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