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The primary data page shows the detailed antibody staining in 76 different cell types for each analyzed antibody. In addition, for each cell type, a knowledge-based annotated protein expression score based on all analyzed antibodies is displayed furthest to the right. The images and annotations can be accessed by clicking on the tissue name or score bar. More information can be found in Assays & Annotation.
The tissues and cell types can be ordered by organ, cell type or alphabetically. If ordered by organ, the tissues are presented in groups according to functional features. If ordered by cell type, the cells are presented in groups related to origin.
This score describes the level of antibody staining observed in the annotated cell types as not detected (n), low (l), medium (m) or high (h). It is based on the staining intensity and fraction of stained cells. The images and annotations can be accessed by clicking on the tissue name or score bar. More information can be found in Assays & Annotation.
Annotated protein expressioni
This score describes a knowledge-based best estimate of the protein expression in the annotated cell types as not detected (n), low (l), medium (m) or high (h). It is a result of stringent evaluation of immunohistochemical staining pattern, RNA data from internal and external sources and available protein/gene characterization data. More information can be found in Assays & Annotation.
Summarizing texts describe the staining pattern for each antibody based on staining intensity, fraction of stained cells and subcellular localization. More information can be found in Assays & Annotation.
HPA054975
Most normal tissues displayed moderate granular cytoplasmic positivity. Subset of cells of gastrointestinal tract, hepatocytes of liver, exocrine glandular cells, adrenal, renal tubules, parathyroid gland, smooth muscle cells, keratinocytes of skin and epidermal cells showed strong positivity. Glial cells were negative.
CAB011464
Most normal tissues displayed moderate to strong nuclear and nucleolar positivity accompanied with cytoplasmic staining in some tissues. Additionally membranous staining was observed in hepatocytes, exocrine pancreas, parathyroid and adrenal cortex.
CAB035990
Moderate cytoplasmic staining was observed in normal tissues. Adrenal gland, renal tubules and bone marrow cells were strongly stained. Most cells in the CNS were weakly stained or negative.
CAB080407
Cytoplasmic positivity was observed in subsets of cells in gastrointestinal tract, lymphoid tissues, squamous epithelia and endometrium.
The Human Protein Atlas project is funded
