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The primary data page shows the detailed antibody staining in 76 different cell types for each analyzed antibody. In addition, for each cell type, a knowledge-based annotated protein expression score based on all analyzed antibodies is displayed furthest to the right. The images and annotations can be accessed by clicking on the tissue name or score bar. More information can be found in Assays & Annotation.
The tissues and cell types can be ordered by organ, cell type or alphabetically. If ordered by organ, the tissues are presented in groups according to functional features. If ordered by cell type, the cells are presented in groups related to origin.
This score describes the level of antibody staining observed in the annotated cell types as not detected (n), low (l), medium (m) or high (h). It is based on the staining intensity and fraction of stained cells. The images and annotations can be accessed by clicking on the tissue name or score bar. More information can be found in Assays & Annotation.
Annotated protein expressioni
This score describes a knowledge-based best estimate of the protein expression in the annotated cell types as not detected (n), low (l), medium (m) or high (h). It is a result of stringent evaluation of immunohistochemical staining pattern, RNA data from internal and external sources and available protein/gene characterization data. More information can be found in Assays & Annotation.
Summarizing texts describe the staining pattern for each antibody based on staining intensity, fraction of stained cells and subcellular localization. More information can be found in Assays & Annotation.
HPA048652
Moderate to strong granular cytoplasmic positivity was displayed by most normal tissues.
HPA055972
Skeletal myocytes showed strong cytoplasmic positivity. Duodenum, appendix, renal tubules and glandular cells of colon showed moderate positivity. Urothelial cells showed moderate cytoplasmic and nuclear positivity. Remaining normal tissues were weakly stained or negative.
HPA055973
The adrenal, Leydig cells and skeletal myocytes showed moderate to strong cytoplasmic staining. Hepatocytes displayed strong cytoplasmic and nuclear positivity. Gastrointestinal tract displayed moderate top strong luminal membranous and cytoplasmic staining. Breast, exocrine pancreas, renal tubules, urothelium and seminal vesicle displayed moderate membranous staining. Remaining normal tissues were weakly stained or negative.