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On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.
Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.
If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.
No data
RNA expressioni
A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.
The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.
Scroll down to view mRNA expression data in more detail.
Consensus:
2.8
nTPM
HPA Brain:
12.5
nTPM
GTEx:
2.8
nTPM
MIDBRAIN - Annotated protein expression
Pending normal tissue analysis
MIDBRAIN - HPA Brain RNA-seq
Max subtype nTPMi
Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.
12.5
Sample id
Sample description
nTPM
Cuneiform nucleus nTPM: 8.2
1830
Male, age 51, unknown
9.4
2219
Male, age 76, both hemispheres
9.1
1833
Male, age 53, unknown
9.0
2828
Female, age 72, unknown
8.8
1870
Female, age 42, unknown
8.5
1827
Male, age 72, unknown
8.2
2666
Male, age 74, left hemisphere
8.0
2411
Female, age 72, unknown
7.6
2019
Male, age 18, unknown
7.3
2586
Male, age 75, left hemisphere
5.8
Dorsal raphe nucleus nTPM: 10.1
2016
Female, age 72, unknown
12.1
2047
Male, age 72, unknown
9.9
2750
Male, age 76, both hemispheres
9.8
1828
Male, age 53, unknown
9.4
2298
Female, age 72, unknown
9.1
Inferior colliculus nTPM: 9.9
2849
Male, age 72, unknown
10.1
2097
Female, age 72, unknown
9.9
1890
Male, age 53, unknown
9.8
1848
Female, age 42, unknown
9.7
Median raphe nucleus nTPM: 11.8
2220
Male, age 76, midline
11.8
Periaquaductal grey, anterior nTPM: 8.9
1947
Male, age 18, unknown
9.8
1795
Male, age 51, unknown
9.4
2502
Female, age 75, unknown
7.6
Periaquaductal grey, dorsal nTPM: 12.5
2850
Male, age 76, both hemispheres
16.8
1840
Male, age 53, unknown
11.7
1831
Male, age 72, unknown
11.2
2464
Female, age 72, unknown
10.1
Periaquaductal grey, lateral nTPM: 12.5
2140
Male, age 76, both hemispheres
14.3
2272
Male, age 74, both hemispheres
12.3
2053
Male, age 18, unknown
11.0
Pretectal area nTPM: 9.4
2273
Male, age 74, both hemispheres
13.4
2224
Female, age 72, unknown
10.7
2316
Male, age 76, right hemisphere
10.7
2825
Male, age 18, unknown
10.3
2407
Male, age 75, both hemispheres
9.3
2667
Female, age 75, unknown
9.2
1944
Female, age 72, unknown
8.6
1815
Male, age 53, unknown
8.4
1816
Male, age 51, unknown
8.1
1817
Female, age 42, unknown
7.7
2007
Male, age 72, unknown
7.2
Red nucleus nTPM: 8.6
2725
Female, age 75, unknown
10.2
1954
Female, age 42, unknown
10.0
2823
Male, age 76, right hemisphere
9.6
1904
Male, age 53, unknown
9.2
2503
Female, age 72, unknown
9.0
1865
Male, age 51, unknown
8.8
2227
Male, age 72, unknown
8.4
2769
Male, age 72, unknown
8.3
1821
Female, age 72, unknown
7.8
2588
Male, age 74, left hemisphere
7.5
2785
Male, age 18, unknown
7.4
2584
Male, age 75, left hemisphere
6.8
Substantia nigra nTPM: 8.6
2699
Male, age 18, unknown
10.6
2241
Male, age 72, unknown
9.9
2590
Female, age 75, unknown
9.2
2409
Female, age 72, unknown
8.9
2583
Male, age 75, right hemisphere
8.7
2665
Male, age 74, both hemispheres
8.2
1941
Male, age 53, unknown
8.0
1916
Female, age 42, unknown
7.8
1851
Male, age 51, unknown
7.5
1889
Female, age 72, unknown
7.5
Superior colliculus nTPM: 8.7
1995
Male, age 72, unknown
10.9
2087
Female, age 72, unknown
9.4
2587
Male, age 74, left hemisphere
9.3
1839
Male, age 51, unknown
9.0
1913
Female, age 42, unknown
8.5
2664
Male, age 75, both hemispheres
8.4
2261
Male, age 18, unknown
8.2
1796
Male, age 53, unknown
7.9
2668
Female, age 75, unknown
7.9
1895
Male, age 76, right hemisphere
7.5
Ventral tegmental area nTPM: 9.0
2021
Male, age 53, unknown
10.8
2218
Male, age 76, both hemispheres
10.2
2223
Female, age 72, unknown
9.1
1942
Male, age 51, unknown
8.8
1915
Female, age 42, unknown
8.3
2410
Female, age 72, unknown
6.6
MIDBRAIN - GTEx RNA-seqi
RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.
Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi
Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.
2.8
GTEx sample id
Sample description
nTPM
Brain - Substantia nigra Average nTPM: 2.8
Samples: 139
Max nTPM: 6.7
Min nTPM: 0.9
Std nTPM: 1.0
Median nTPM: 2.7
The Human Protein Atlas project is funded
