MIDBRAIN - Expression summary
Protein expressioni No data
RNA expressioni
Consensus:6.3 nTPM
HPA Brain:68.7 nTPM
GTEx:6.3 nTPM
FANTOM5:53.6 Scaled Tags Per Million
Pig:20.8 nTPM
Mouse:18.6 nTPM
Allen mouse:1.4 Expression energy
BRAIN - SINGLE CELL RNA EXPRESSION
Brain excitatory neuronsBrain inhibitory neuronsOther brain neuronsAstrocytesBergmann gliaOligodendrocyte progenitor cellsOligodendrocytesMicrogliaEpendymal cellsChoroid plexus epithelial cellsVascular endothelial cellsPericytesVascular smooth muscle cellsFibroblastsMonocytesMacrophagesT-cellsB-cellsNK-cells02004006008001,0001,2001,400nCPM

MIDBRAIN - HPA Brain RNA-seq
Max subtype nTPMi 68.7
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 57.9
2666 Male, age 74, left hemisphere 66.2
2586 Male, age 75, left hemisphere 63.9
2828 Female, age 72, unknown 61.5
1833 Male, age 53, unknown 60.9
2219 Male, age 76, both hemispheres 60.8
1827 Male, age 72, unknown 60.6
1870 Female, age 42, unknown 57.7
1830 Male, age 51, unknown 57.5
2411 Female, age 72, unknown 45.6
2019 Male, age 18, unknown 44.4
Dorsal raphe nucleus
nTPM: 59.5
2047 Male, age 72, unknown 71.3
2016 Female, age 72, unknown 62.5
1828 Male, age 53, unknown 58.5
2298 Female, age 72, unknown 57.2
2750 Male, age 76, both hemispheres 48.0
Inferior colliculus
nTPM: 68.6
2849 Male, age 72, unknown 86.4
1848 Female, age 42, unknown 70.3
1890 Male, age 53, unknown 65.0
2097 Female, age 72, unknown 52.6
Median raphe nucleus
nTPM: 54.3
2220 Male, age 76, midline 54.3
Periaquaductal grey, anterior
nTPM: 49.8
1947 Male, age 18, unknown 57.0
1795 Male, age 51, unknown 50.0
2502 Female, age 75, unknown 42.4
Periaquaductal grey, dorsal
nTPM: 63.5
1840 Male, age 53, unknown 84.3
2850 Male, age 76, both hemispheres 68.0
2464 Female, age 72, unknown 52.8
1831 Male, age 72, unknown 48.8
Periaquaductal grey, lateral
nTPM: 64.2
2140 Male, age 76, both hemispheres 70.8
2053 Male, age 18, unknown 66.6
2272 Male, age 74, both hemispheres 55.1
Pretectal area
nTPM: 60.7
2407 Male, age 75, both hemispheres 90.5
2825 Male, age 18, unknown 66.8
2316 Male, age 76, right hemisphere 61.6
2273 Male, age 74, both hemispheres 61.4
2667 Female, age 75, unknown 60.5
2224 Female, age 72, unknown 56.8
1816 Male, age 51, unknown 55.5
1817 Female, age 42, unknown 54.7
1815 Male, age 53, unknown 53.9
2007 Male, age 72, unknown 53.3
1944 Female, age 72, unknown 52.6
Red nucleus
nTPM: 51.0
2584 Male, age 75, left hemisphere 80.5
2725 Female, age 75, unknown 55.5
1954 Female, age 42, unknown 53.9
2588 Male, age 74, left hemisphere 51.0
2769 Male, age 72, unknown 49.2
2823 Male, age 76, right hemisphere 48.9
1865 Male, age 51, unknown 47.1
1821 Female, age 72, unknown 46.4
2227 Male, age 72, unknown 46.2
1904 Male, age 53, unknown 45.4
2503 Female, age 72, unknown 43.9
2785 Male, age 18, unknown 43.5
Substantia nigra
nTPM: 68.7
2665 Male, age 74, both hemispheres 86.8
2699 Male, age 18, unknown 85.1
2583 Male, age 75, right hemisphere 82.0
2241 Male, age 72, unknown 77.7
1916 Female, age 42, unknown 66.8
1851 Male, age 51, unknown 66.0
2590 Female, age 75, unknown 61.1
2409 Female, age 72, unknown 56.4
1889 Female, age 72, unknown 53.9
1941 Male, age 53, unknown 50.8
Superior colliculus
nTPM: 59.7
2664 Male, age 75, both hemispheres 80.7
1796 Male, age 53, unknown 70.6
2668 Female, age 75, unknown 68.0
1839 Male, age 51, unknown 62.9
2587 Male, age 74, left hemisphere 59.0
2087 Female, age 72, unknown 57.1
2261 Male, age 18, unknown 52.0
1995 Male, age 72, unknown 49.8
1895 Male, age 76, right hemisphere 48.7
1913 Female, age 42, unknown 48.2
Ventral tegmental area
nTPM: 64.1
1915 Female, age 42, unknown 70.2
2223 Female, age 72, unknown 69.6
1942 Male, age 51, unknown 69.5
2021 Male, age 53, unknown 63.2
2218 Male, age 76, both hemispheres 60.9
2410 Female, age 72, unknown 51.3

MIDBRAIN - GTEx RNA-seqi
Max subtype nTPMi 6.3
GTEx sample id Sample description nTPM
4.55.57.31.811.4024681012141618
Brain - Substantia nigra
Average nTPM: 6.3
Samples: 183

Max nTPM: 19.8
Min nTPM: 1.8
Std nTPM: 2.8
Median nTPM: 5.5
GTEX-1PWST-0011-R2b-SM-F3K5I 70-79 years, male 19.8
GTEX-1O9I2-0011-R2b-SM-F3K53 50-59 years, male 17.6
GTEX-X4EP-0011-R2B-SM-3P625 60-69 years, female 17.1
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 16.4
GTEX-WVLH-0011-R2A-SM-3MJFJ 50-59 years, male 15.3
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 15.0
GTEX-1N2EF-0011-R2b-SM-F6482 60-69 years, male 13.4
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 11.4
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 11.2
GTEX-11TTK-0011-R2b-SM-GJ3PU 60-69 years, female 11.1
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 10.9
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MIDBRAIN - FANTOM5 CAGEi
Max subtype Scaled Tags Per Millioni 53.6
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 53.6
FF:10158-103A5 76 years, female 53.6

MIDBRAIN - Pig RNA-seqi
Max subtype nTPMi 20.8
Pig sample Sample description nTPM
17.420.023.016.524.7024681012141618202224
 		Substantia nigra
nTPM: 20.3
Samples: 4

Max nTPM: 24.7
Min nTPM: 16.5
Sample A Female 24.7
Sample B Female 17.7
Sample C Male 22.4
Sample D Male 16.5
15.418.421.013.921.602468101214161820
 		Midbrain
nTPM: 18.1
Samples: 4

Max nTPM: 21.6
Min nTPM: 13.9
Sample A Female 13.9
Sample B Female 21.6
Sample C Male 15.9
Sample D Male 20.8
19.920.621.719.222.80246810121416182022
 		Periaqueductal gray
nTPM: 20.9
Samples: 3

Max nTPM: 22.8
Min nTPM: 19.2
Sample B Female 20.6
Sample C Male 22.8
Sample D Male 19.2
10.613.616.97.720.302468101214161820
 		Superior colliculi
nTPM: 13.8
Samples: 4

Max nTPM: 20.3
Min nTPM: 7.7
Sample A Female 20.3
Sample B Female 7.7
Sample C Male 11.5
Sample D Male 15.7

MIDBRAIN - Mouse RNA-seqi
Max subtype nTPMi 18.6
Mouse sample Sample description nTPM
18.018.919.615.820.702468101214161820
 		Midbrain
nTPM: 18.6
Samples: 4

Max nTPM: 20.7
Min nTPM: 15.8
Sample A Male 15.8
Sample B Male 19.2
Sample C Female 20.7
Sample D Female 18.7

MIDBRAIN - Allen Mouse ISHi
Max subtype Expression energyi 1.4
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 1.4
71281301 Antisense, RP_050818_02_D04, Mouse strain C57BL/6J (56 days, male) 1.5
75080997 Antisense, RP_060412_04_H02, Mouse strain C57BL/6J (56 days, male) 1.3

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