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The primary data page shows the detailed antibody staining in 76 different cell types for each analyzed antibody. In addition, for each cell type, a knowledge-based annotated protein expression score based on all analyzed antibodies is displayed furthest to the right. The images and annotations can be accessed by clicking on the tissue name or score bar. More information can be found in Assays & Annotation.
The tissues and cell types can be ordered by organ, cell type or alphabetically. If ordered by organ, the tissues are presented in groups according to functional features. If ordered by cell type, the cells are presented in groups related to origin.
This score describes the level of antibody staining observed in the annotated cell types as not detected (n), low (l), medium (m) or high (h). It is based on the staining intensity and fraction of stained cells. The images and annotations can be accessed by clicking on the tissue name or score bar. More information can be found in Assays & Annotation.
Annotated protein expressioni
This score describes a knowledge-based best estimate of the protein expression in the annotated cell types as not detected (n), low (l), medium (m) or high (h). It is a result of stringent evaluation of immunohistochemical staining pattern, RNA data from internal and external sources and available protein/gene characterization data. More information can be found in Assays & Annotation.
Summarizing texts describe the staining pattern for each antibody based on staining intensity, fraction of stained cells and subcellular localization. More information can be found in Assays & Annotation.
HPA040465
Spleen, bone marrow poietic cells and lymphoid cells outside reaction center showed strong cytoplasmic immunoreactivity. Salivary gland, gall bladder, pancreatic islets, prostate and uterine glands displayed strong cytoplasmic positivity with a granular pattern. Distinct membranous staining sometimes with additional granular cytoplasmic positivity was observed in gastrointestinal tract. Cilia of fallopian tube and respiratory epithelia were strongly stained. Remaining normal tissues showed moderate granular staining in a fraction of cell or were negative.
HPA077912
Moderate to strong cytoplasmic positivity was mainly observed in subsets of immune cells in lymphoid and peripheral tissues. Strong staining was also observed in cilia of bronchus and fallopian tube and in luminal membranes of gastrointestinal tract.
The Human Protein Atlas project is funded
