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The primary data page shows the detailed antibody staining in 76 different cell types for each analyzed antibody. In addition, for each cell type, a knowledge-based annotated protein expression score based on all analyzed antibodies is displayed furthest to the right. The images and annotations can be accessed by clicking on the tissue name or score bar. More information can be found in Assays & Annotation.
The tissues and cell types can be ordered by organ, cell type or alphabetically. If ordered by organ, the tissues are presented in groups according to functional features. If ordered by cell type, the cells are presented in groups related to origin.
This score describes the level of antibody staining observed in the annotated cell types as not detected (n), low (l), medium (m) or high (h). It is based on the staining intensity and fraction of stained cells. The images and annotations can be accessed by clicking on the tissue name or score bar. More information can be found in Assays & Annotation.
Annotated protein expressioni
This score describes a knowledge-based best estimate of the protein expression in the annotated cell types as not detected (n), low (l), medium (m) or high (h). It is a result of stringent evaluation of immunohistochemical staining pattern, RNA data from internal and external sources and available protein/gene characterization data. More information can be found in Assays & Annotation.
Summarizing texts describe the staining pattern for each antibody based on staining intensity, fraction of stained cells and subcellular localization. More information can be found in Assays & Annotation.
HPA027586
Strong membranous positivity combined with cases of cytoplasmic staining was observed in respiratory epithelia, gastrointestinal glands, gallbladder, pancreas, urothelia, fallopian tube and most male genitalia. Cells in CNS, lymphoid tissues, myocytes and liver were negative.
HPA027587
Weak to moderate membranous, nuclear and cytoplasmic positivity was seen in normal tissues. Gastrointestinal tract, gallbladder, exocrine pancreas and seminal vescicle were strongly stained. Glial cells, lymphoid tissue, squamous epithelia and myocytes were negative.
HPA027657
A majority of normal tissues showed moderate to strong membranous immunoreactivity with additional cytoplasmic positivity in some cases. Liver, pancreatic islet cells, bone marrow, cells in CNS and lymphoid tissues were negative.
CAB017193
Most normal tissues showed moderate cytoplasmic and a slightly stronger membranous immunoreactivity. Most luminal membranes and neurons in CNS were strongly stained.
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