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MRPL50
HPA
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                                          • SUMMARY

                                          • TISSUE

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                                          • MRPL50
                                          TISSUE PRIMARY DATA TISSUES Show tissue menu
                                          ADIPOSE TISSUE ADRENAL GLAND AMYGDALA APPENDIX BASAL GANGLIA BLOOD VESSEL BONE MARROW BREAST BRONCHUS CEREBELLUM CEREBRAL CORTEX CERVIX CHOROID PLEXUS COLON
                                          DUODENUM ENDOMETRIUM EPIDIDYMIS ESOPHAGUS FALLOPIAN TUBE GALLBLADDER HEART MUSCLE HIPPOCAMPAL FORMATION HYPOTHALAMUS KIDNEY LIVER LUNG LYMPH NODE MIDBRAIN
                                          NASOPHARYNX ORAL MUCOSA OVARY PANCREAS PARATHYROID GLAND PITUITARY GLAND PLACENTA PROSTATE RECTUM RETINA SALIVARY GLAND SEMINAL VESICLE SKELETAL MUSCLE SKIN
                                          SMALL INTESTINE SMOOTH MUSCLE SOFT TISSUE SPINAL CORD SPLEEN STOMACH TESTIS THYMUS THYROID GLAND TONGUE TONSIL URINARY BLADDER VAGINA
                                          ANTIBODIES
                                          AND
                                          VALIDATION
                                          Dictionary
                                          Tissue proteome
                                          Tissue methods
                                          ANTIBODY PRIMARY DATAi

                                          The primary data page shows the detailed antibody staining in 76 different cell types for each analyzed antibody. In addition, for each cell type, a knowledge-based annotated protein expression score based on all analyzed antibodies is displayed furthest to the right. The images and annotations can be accessed by clicking on the tissue name or score bar. More information can be found here

                                          The tissues and cell types can be ordered by organ, cell type or alphabetically. If ordered by organ, the tissues are presented in groups according to functional features. If ordered by cell type, the cells are presented in groups related to origin.

                                          For histological reference, visit the histological dictionary.

                                          Antibodies in assayi

                                          The internal antibody ID for the antibody/antibodies available for this specific target, click link for more antibody information.

                                          HPA022925
                                          Tissue presentation order  
                                          Organ
                                          Cell type
                                          Alphabetical
                                          Tissue Antibody stainingi

                                          This score describes the level of antibody staining observed in the annotated cell types as not detected (n), low (l), medium (m) or high (h). It is based on the staining intensity and fraction of stained cells. The images and annotations can be accessed by clicking on the tissue name or score bar. More information can be found here.

                                          Annotated protein expressioni

                                          This score describes a knowledge-based best estimate of the protein expression in the annotated cell types as not detected (n), low (l), medium (m) or high (h). It is a result of stringent evaluation of immunohistochemical staining pattern, RNA data from internal and external sources and available protein/gene characterization data. More information can be found here.

                                          HPA022925

                                          h
                                          m
                                          l
                                          n
                                          h
                                          m
                                          l
                                          n
                                          Brain
                                          Cerebral cortex Neuronal cells
                                          Cerebral cortex Endothelial cells
                                          Cerebral cortex Glial cells
                                          Cerebral cortex Neuropil
                                          Hippocampus Neuronal cells
                                          Hippocampus Glial cells
                                          Caudate Neuronal cells
                                          Caudate Glial cells
                                          Cerebellum Purkinje cells
                                          Cerebellum Cells in granular layer
                                          Cerebellum Cells in molecular layer
                                          Endocrine tissues
                                          Thyroid gland Glandular cells
                                          Parathyroid gland Glandular cells
                                          Adrenal gland Glandular cells
                                          Respiratory system
                                          Nasopharynx Respiratory epithelial cells
                                          Bronchus Respiratory epithelial cells
                                          Lung Alveolar cells
                                          Lung Macrophages
                                          Proximal digestive tract
                                          Oral mucosa Squamous epithelial cells
                                          Salivary gland Glandular cells
                                          Esophagus Squamous epithelial cells
                                          Gastrointestinal tract
                                          Stomach 1 Glandular cells
                                          Stomach 2 Glandular cells
                                          Duodenum Glandular cells
                                          Small intestine Glandular cells
                                          Colon Endothelial cells
                                          Colon Glandular cells
                                          Colon Peripheral nerve/ganglion
                                          Rectum Glandular cells
                                          Liver & Gallbladder
                                          Liver Hepatocytes
                                          Liver Cholangiocytes
                                          Gallbladder Glandular cells
                                          Pancreas
                                          Pancreas Exocrine glandular cells
                                          Pancreas Pancreatic endocrine cells
                                          Kidney & Urinary bladder
                                          Kidney Cells in glomeruli
                                          Kidney Cells in tubules
                                          Urinary bladder Urothelial cells
                                          Male reproductive system
                                          Testis Elongated or late spermatids
                                          Testis Leydig cells
                                          Testis Pachytene spermatocytes
                                          Testis Peritubular cells
                                          Testis Preleptotene spermatocytes
                                          Testis Round or early spermatids
                                          Testis Sertoli cells
                                          Testis Spermatogonia cells
                                          Epididymis Glandular cells
                                          Prostate Glandular cells
                                          Seminal vesicle Glandular cells
                                          Breast & female reproductive system
                                          Breast Adipocytes
                                          Breast Glandular cells
                                          Breast Myoepithelial cells
                                          Vagina Squamous epithelial cells
                                          Cervix Squamous epithelial cells
                                          Cervix Glandular cells
                                          Endometrium 1 Glandular cells
                                          Endometrium 1 Cells in endometrial stroma
                                          Endometrium 2 Glandular cells
                                          Endometrium 2 Cells in endometrial stroma
                                          Fallopian tube Glandular cells
                                          Ovary Follicle cells
                                          Ovary Ovarian stroma cells
                                          Placenta Trophoblastic cells
                                          Placenta Decidual cells
                                          Muscle & Vascular tissue
                                          Heart muscle Cardiomyocytes
                                          Skeletal muscle Myocytes
                                          Smooth muscle Smooth muscle cells
                                          Connective & Soft tissue
                                          Adipose tissue Adipocytes
                                          Soft tissue 1 Peripheral nerve
                                          Soft tissue 1 Chondrocytes
                                          N/A
                                          Soft tissue 1 Fibroblasts
                                          Soft tissue 2 Fibroblasts
                                          Soft tissue 2 Chondrocytes
                                          N/A
                                          Soft tissue 2 Peripheral nerve
                                          Skin
                                          Skin 1 Fibroblasts
                                          Skin 1 Keratinocytes
                                          Skin 1 Langerhans
                                          Skin 1 Melanocytes
                                          Skin 2 Epidermal cells
                                          Bone marrow & Lymphoid tissues
                                          Appendix Glandular cells
                                          Appendix Lymphoid tissue
                                          Bone marrow Hematopoietic cells
                                          Lymph node Germinal center cells
                                          Lymph node Non-germinal center cells
                                          Tonsil Germinal center cells
                                          Tonsil Non-germinal center cells
                                          Tonsil Squamous epithelial cells
                                          Spleen Cells in white pulp
                                          Spleen Cells in red pulp
                                           
                                          Staining summaryi

                                          Summarizing texts describe the staining pattern for each antibody based on staining intensity, fraction of stained cells and subcellular localization. More information can be found here.

                                          Most normal tissues displayed moderate to strong cytoplasmic positivity combined with cases of nuclear staining. Bile duct cells, ovarian and endometrial stroma cells were weakly stained or negative.

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