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The primary data page shows the detailed antibody staining in 76 different cell types for each analyzed antibody. In addition, for each cell type, a knowledge-based annotated protein expression score based on all analyzed antibodies is displayed furthest to the right. The images and annotations can be accessed by clicking on the tissue name or score bar. More information can be found in Assays & Annotation.
The tissues and cell types can be ordered by organ, cell type or alphabetically. If ordered by organ, the tissues are presented in groups according to functional features. If ordered by cell type, the cells are presented in groups related to origin.
This score describes the level of antibody staining observed in the annotated cell types as not detected (n), low (l), medium (m) or high (h). It is based on the staining intensity and fraction of stained cells. The images and annotations can be accessed by clicking on the tissue name or score bar. More information can be found in Assays & Annotation.
Annotated protein expressioni
This score describes a knowledge-based best estimate of the protein expression in the annotated cell types as not detected (n), low (l), medium (m) or high (h). It is a result of stringent evaluation of immunohistochemical staining pattern, RNA data from internal and external sources and available protein/gene characterization data. More information can be found in Assays & Annotation.
Summarizing texts describe the staining pattern for each antibody based on staining intensity, fraction of stained cells and subcellular localization. More information can be found in Assays & Annotation.
HPA027134
Moderate cytoplasmic positivity was observed in renal tubules while cells in glomeruli and the intestine showed strong membranous staining. Neuropil in the CNS was distinctly stained. The remaining normal tissues were negative.
HPA027150
Strong cytoplasmic positivity was observed in enteroendocrine cells and subsets of cells in the adrenal gland. Neuropil in the CNS was distinctly stained. Superficial layers in squamous epithelia, basal seminiferous duct cells, skeletal and cardiac muscle cells showed moderate cytoplasmic staining. Remaining normal tissues were negative.
HPA029859
Proximal renal tubules showed strong cytoplasmic positivity while hepatocytes displayed strong nuclear and cytoplasmic staining. Gall bladder, adrenal gland, skeletal muscle, subsets of cells in spleenic red pulp and bone marrow poietic cells were moderately stained. Remaining normal cells were generally negative.
CAB022343
Most normal tissues were negative. Basement membranes and neuropil were moderately stained.
The Human Protein Atlas project is funded
