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The primary data page shows the detailed antibody staining in 76 different cell types for each analyzed antibody. In addition, for each cell type, a knowledge-based annotated protein expression score based on all analyzed antibodies is displayed furthest to the right. The images and annotations can be accessed by clicking on the tissue name or score bar. More information can be found in Assays & Annotation.
The tissues and cell types can be ordered by organ, cell type or alphabetically. If ordered by organ, the tissues are presented in groups according to functional features. If ordered by cell type, the cells are presented in groups related to origin.
This score describes the level of antibody staining observed in the annotated cell types as not detected (n), low (l), medium (m) or high (h). It is based on the staining intensity and fraction of stained cells. The images and annotations can be accessed by clicking on the tissue name or score bar. More information can be found in Assays & Annotation.
Annotated protein expressioni
This score describes a knowledge-based best estimate of the protein expression in the annotated cell types as not detected (n), low (l), medium (m) or high (h). It is a result of stringent evaluation of immunohistochemical staining pattern, RNA data from internal and external sources and available protein/gene characterization data. More information can be found in Assays & Annotation.
Summarizing texts describe the staining pattern for each antibody based on staining intensity, fraction of stained cells and subcellular localization. More information can be found in Assays & Annotation.
HPA038878
Moderate cytoplasmic and nuclear positivity was displayed in gastro-intestinal glands, adrenal gland and exocrine glandular cells. Glandular cells of uterine cervix, urothelium and squamous epithelium of tonsil showed moderate nuclear staining. Strong cytoplasmic immunoreactivity was displayed in Purkinje cells and renal tubules while skeletal myocytes and prostate were moderately stained. Remaining normal tissues were weakly stained or generally negative.
HPA038879
Normal cells displayed moderate to strong cytoplasmic positivity. Additional membranous staining was observed in exocrine pancreas, respiratory epithelial cells, epididymis, fallopian tube and stomach. Glial cells and adipocytes were weakly stained or negative.
CAB034211
Most of the normal tissues displayed weak to moderate cytoplasmic positivity. Strong immunoreactivity was observed in ducts of salivary glands. Alveolar cells, bile ducts, glandular cells in female genital tract, lymphoid tissues and glial cells were negative.