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The primary data page shows the detailed antibody staining in 76 different cell types for each analyzed antibody. In addition, for each cell type, a knowledge-based annotated protein expression score based on all analyzed antibodies is displayed furthest to the right. The images and annotations can be accessed by clicking on the tissue name or score bar. More information can be found in Assays & Annotation.
The tissues and cell types can be ordered by organ, cell type or alphabetically. If ordered by organ, the tissues are presented in groups according to functional features. If ordered by cell type, the cells are presented in groups related to origin.
This score describes the level of antibody staining observed in the annotated cell types as not detected (n), low (l), medium (m) or high (h). It is based on the staining intensity and fraction of stained cells. The images and annotations can be accessed by clicking on the tissue name or score bar. More information can be found in Assays & Annotation.
Annotated protein expressioni
This score describes a knowledge-based best estimate of the protein expression in the annotated cell types as not detected (n), low (l), medium (m) or high (h). It is a result of stringent evaluation of immunohistochemical staining pattern, RNA data from internal and external sources and available protein/gene characterization data. More information can be found in Assays & Annotation.
Summarizing texts describe the staining pattern for each antibody based on staining intensity, fraction of stained cells and subcellular localization. More information can be found in Assays & Annotation.
HPA006641
Islets of Langerhans, cells in molecular layer of cerebellum, subset of cells in gastrointestinal tract and bronchus exhibited strong cytoplasmic and nuclear positivity. Follicular cells of ovary and bile ducts were moderately stained. Remaining normal tissues were negative.
CAB004005
Most normal tissues were negative. Strong cytoplasmic and nuclear positivity was observed in pancreatic islets, in endocrine cells of the gastrointestinal tract and in neuronal cells in the molecular cell layer of cerebellum.
CAB062563
Islets of Langerhans showed moderate cytoplasmic and nuclear positivity. Subset of cells in gastrointestinal tract displayed moderate to strong cytoplasmic and nuclear staining. Other normal tissues were negative.
CAB068232
A subset of cells in gastrointestinal tract along with islets of Langerhans showed strong cytoplasmic and nuclear staining. Cells in molecular layer of cerebellum displayed moderate nuclear positivity while a subset of cells in bile ducts and lung exhibited weak immunoreactivity. Remaining normal tissues were negative.
The Human Protein Atlas project is funded
