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General description of the gene and the encoded protein(s) using information from HGNC and Ensembl, as well as predictions made by the Human Protein Atlas project.
Gene namei
Official gene symbol, which is typically a short form of the gene name, according to HGNC.
Assigned HPA protein class(es) for the encoded protein(s).
Disease related genes Enzymes Plasma proteins Potential drug targets RAS pathway related proteins
Predicted locationi
All transcripts of all genes have been analyzed regarding the location(s) of corresponding protein based on prediction methods for signal peptides and transmembrane regions.
Genes with at least one transcript predicted to encode a secreted protein, according to prediction methods or to UniProt location data, have been further annotated and classified with the aim to determine if the corresponding protein(s) are secreted or actually retained in intracellular locations or membrane-attached.
Remaining genes, with no transcript predicted to encode a secreted protein, will be assigned the prediction-based location(s).
The annotated location overrules the predicted location, so that a gene encoding a predicted secreted protein that has been annotated as intracellular will have intracellular as the final location.
Gene information from Ensembl and Entrez, as well as links to available gene identifiers are displayed here. Information was retrieved from Ensembl if not indicated otherwise.
Chromosome
1
Cytoband
p36.12
Chromosome location (bp)
22052627 - 22101360
Number of transcriptsi
Number of protein-coding transcripts from the gene as defined by Ensembl.
Useful information about the protein provided by UniProt.
Plasma membrane-associated small GTPase which cycles between an active GTP-bound and an inactive GDP-bound state. In active state binds to a variety of effector proteins to regulate cellular responses. Involved in epithelial cell polarization processes. Regulates the bipolar attachment of spindle microtubules to kinetochores before chromosome congression in metaphase 1. Regulates cell migration 2,3. In neurons, plays a role in the extension and maintenance of the formation of filopodia, thin and actin-rich surface projections 4. Required for DOCK10-mediated spine formation in Purkinje cells and hippocampal neurons. In podocytes, facilitates filopodia and podosomes formation upon DOCK11-activation 5. Upon activation by CaMKII, modulates dendritic spine structural plasticity by relaying CaMKII transient activation to synapse-specific, long-term signaling (By similarity). Also plays a role in phagocytosis through organization of the F-actin cytoskeleton associated with forming phagocytic cups 6. Upon activation by PLEKHG4B, involved in actin cytoskeletal remodeling during epithelial cell-cell junction formation 7....show less
Molecular function (UniProt)i
Keywords assigned by UniProt to proteins due to their particular molecular function.
Hydrolase
Biological process (UniProt)i
Keywords assigned by UniProt to proteins because they are involved in a particular biological process.
Differentiation, Neurogenesis
Ligand (UniProt)i
Keywords assigned by UniProt to proteins because they bind, are associated with, or whose activity is dependent of some molecule.
GTP-binding, Nucleotide-binding
Gene summary (Entrez)i
Useful information about the gene from Entrez
The protein encoded by this gene is a small GTPase of the Rho-subfamily, which regulates signaling pathways that control diverse cellular functions including cell morphology, migration, endocytosis and cell cycle progression. This protein is highly similar to Saccharomyces cerevisiae Cdc 42, and is able to complement the yeast cdc42-1 mutant. The product of oncogene Dbl was reported to specifically catalyze the dissociation of GDP from this protein. This protein could regulate actin polymerization through its direct binding to Neural Wiskott-Aldrich syndrome protein (N-WASP), which subsequently activates Arp2/3 complex. Alternative splicing of this gene results in multiple transcript variants. Pseudogenes of this gene have been identified on chromosomes 3, 4, 5, 7, 8 and 20. [provided by RefSeq, Apr 2013]...show less
PROTEIN INFORMATIONi
The protein information section displays alternative protein-coding transcripts (splice variants) encoded by this gene according to the Ensembl database.
The Splice variant identifier links to the Ensembl website protein summary for the selected splice variant. The data in the Swissprot and TrEMBL columns links to corresponding pages in the UniProt database.
The protein classes assigned to this protein are shown if expanding the data in the protein class column. Parent protein classes are in bold font and subclasses are listed under the parent class.
The length of the protein (amino acid residues according to Ensembl), molecular mass (kDalton), predicted signal peptide and number of predicted transmembrane region(s) according to in-house majority decision methods based on sets of predictors are also reported.
P60953 [Direct mapping] Cell division control protein 42 homolog
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A0A024RAE6 [Target identity:100%; Query identity:100%] Cell division control protein 42 homolog
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Enzymes ENZYME proteins Hydrolases Predicted intracellular proteins Intracellular proteins predicted by MDM and MDSEC Plasma proteins RAS pathway related proteins Disease related genes Potential drug targets Mapped to neXtProt neXtProt - Evidence at protein level Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014)
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GO:0000139[Golgi membrane] GO:0000166[nucleotide binding] GO:0003924[GTPase activity] GO:0003925[G protein activity] GO:0005515[protein binding] GO:0005525[GTP binding] GO:0005737[cytoplasm] GO:0005789[endoplasmic reticulum membrane] GO:0005813[centrosome] GO:0005815[microtubule organizing center] GO:0005819[spindle] GO:0005829[cytosol] GO:0005856[cytoskeleton] GO:0005886[plasma membrane] GO:0005925[focal adhesion] GO:0006897[endocytosis] GO:0006911[phagocytosis, engulfment] GO:0007015[actin filament organization] GO:0007030[Golgi organization] GO:0007163[establishment or maintenance of cell polarity] GO:0007229[integrin-mediated signaling pathway] GO:0007264[small GTPase mediated signal transduction] GO:0007399[nervous system development] GO:0009653[anatomical structure morphogenesis] GO:0010591[regulation of lamellipodium assembly] GO:0010592[positive regulation of lamellipodium assembly] GO:0016020[membrane] GO:0016567[protein ubiquitination] GO:0016787[hydrolase activity] GO:0017119[Golgi transport complex] GO:0019901[protein kinase binding] GO:0021762[substantia nigra development] GO:0030036[actin cytoskeleton organization] GO:0030154[cell differentiation] GO:0030175[filopodium] GO:0030225[macrophage differentiation] GO:0030307[positive regulation of cell growth] GO:0030335[positive regulation of cell migration] GO:0030425[dendrite] GO:0030496[midbody] GO:0031274[positive regulation of pseudopodium assembly] GO:0031333[negative regulation of protein-containing complex assembly] GO:0031996[thioesterase binding] GO:0032427[GBD domain binding] GO:0032467[positive regulation of cytokinesis] GO:0032488[Cdc42 protein signal transduction] GO:0032991[protein-containing complex] GO:0034191[apolipoprotein A-I receptor binding] GO:0034329[cell junction assembly] GO:0036464[cytoplasmic ribonucleoprotein granule] GO:0038189[neuropilin signaling pathway] GO:0042802[identical protein binding] GO:0042995[cell projection] GO:0043005[neuron projection] GO:0043025[neuronal cell body] GO:0043197[dendritic spine] GO:0043227[membrane-bounded organelle] GO:0044788[modulation by host of viral process] GO:0045198[establishment of epithelial cell apical/basal polarity] GO:0048549[positive regulation of pinocytosis] GO:0051130[positive regulation of cellular component organization] GO:0051233[spindle midzone] GO:0051301[cell division] GO:0051489[regulation of filopodium assembly] GO:0051491[positive regulation of filopodium assembly] GO:0051492[regulation of stress fiber assembly] GO:0051496[positive regulation of stress fiber assembly] GO:0051683[establishment of Golgi localization] GO:0051988[regulation of attachment of spindle microtubules to kinetochore] GO:0060071[Wnt signaling pathway, planar cell polarity pathway] GO:0060997[dendritic spine morphogenesis] GO:0061630[ubiquitin protein ligase activity] GO:0070062[extracellular exosome] GO:0071944[cell periphery] GO:0072384[organelle transport along microtubule] GO:0072686[mitotic spindle] GO:0099563[modification of synaptic structure] GO:1900026[positive regulation of substrate adhesion-dependent cell spreading] GO:2000251[positive regulation of actin cytoskeleton reorganization]
P60953 [Direct mapping] Cell division control protein 42 homolog
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A0A024RAA5 [Target identity:100%; Query identity:100%] Cell division control protein 42 homolog
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Enzymes ENZYME proteins Hydrolases Predicted intracellular proteins Intracellular proteins predicted by MDM and MDSEC Plasma proteins RAS pathway related proteins Disease related genes Potential drug targets Mapped to neXtProt neXtProt - Evidence at protein level Protein evidence (Ezkurdia et al 2014)
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GO:0000139[Golgi membrane] GO:0000166[nucleotide binding] GO:0003924[GTPase activity] GO:0003925[G protein activity] GO:0005515[protein binding] GO:0005525[GTP binding] GO:0005737[cytoplasm] GO:0005789[endoplasmic reticulum membrane] GO:0005813[centrosome] GO:0005815[microtubule organizing center] GO:0005819[spindle] GO:0005829[cytosol] GO:0005856[cytoskeleton] GO:0005886[plasma membrane] GO:0005925[focal adhesion] GO:0006897[endocytosis] GO:0006911[phagocytosis, engulfment] GO:0007015[actin filament organization] GO:0007030[Golgi organization] GO:0007163[establishment or maintenance of cell polarity] GO:0007229[integrin-mediated signaling pathway] GO:0007264[small GTPase mediated signal transduction] GO:0007399[nervous system development] GO:0009653[anatomical structure morphogenesis] GO:0010591[regulation of lamellipodium assembly] GO:0010592[positive regulation of lamellipodium assembly] GO:0016020[membrane] GO:0016567[protein ubiquitination] GO:0016787[hydrolase activity] GO:0017119[Golgi transport complex] GO:0019901[protein kinase binding] GO:0021762[substantia nigra development] GO:0030036[actin cytoskeleton organization] GO:0030154[cell differentiation] GO:0030175[filopodium] GO:0030225[macrophage differentiation] GO:0030307[positive regulation of cell growth] GO:0030335[positive regulation of cell migration] GO:0030425[dendrite] GO:0030496[midbody] GO:0031274[positive regulation of pseudopodium assembly] GO:0031333[negative regulation of protein-containing complex assembly] GO:0031996[thioesterase binding] GO:0032427[GBD domain binding] GO:0032467[positive regulation of cytokinesis] GO:0032488[Cdc42 protein signal transduction] GO:0032991[protein-containing complex] GO:0034191[apolipoprotein A-I receptor binding] GO:0034329[cell junction assembly] GO:0036464[cytoplasmic ribonucleoprotein granule] GO:0038189[neuropilin signaling pathway] GO:0042802[identical protein binding] GO:0042995[cell projection] GO:0043005[neuron projection] GO:0043025[neuronal cell body] GO:0043197[dendritic spine] GO:0043227[membrane-bounded organelle] GO:0044788[modulation by host of viral process] GO:0045198[establishment of epithelial cell apical/basal polarity] GO:0048549[positive regulation of pinocytosis] GO:0051130[positive regulation of cellular component organization] GO:0051233[spindle midzone] GO:0051301[cell division] GO:0051489[regulation of filopodium assembly] GO:0051491[positive regulation of filopodium assembly] GO:0051492[regulation of stress fiber assembly] GO:0051496[positive regulation of stress fiber assembly] GO:0051683[establishment of Golgi localization] GO:0051988[regulation of attachment of spindle microtubules to kinetochore] GO:0060071[Wnt signaling pathway, planar cell polarity pathway] GO:0060997[dendritic spine morphogenesis] GO:0061630[ubiquitin protein ligase activity] GO:0070062[extracellular exosome] GO:0071944[cell periphery] GO:0072384[organelle transport along microtubule] GO:0072686[mitotic spindle] GO:0099563[modification of synaptic structure] GO:1900026[positive regulation of substrate adhesion-dependent cell spreading] GO:2000251[positive regulation of actin cytoskeleton reorganization]
P60953 [Direct mapping] Cell division control protein 42 homolog
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A0A024RAA5 [Target identity:100%; Query identity:100%] Cell division control protein 42 homolog
Show all
Enzymes ENZYME proteins Hydrolases Predicted intracellular proteins Intracellular proteins predicted by MDM and MDSEC Plasma proteins RAS pathway related proteins Disease related genes Potential drug targets Mapped to neXtProt neXtProt - Evidence at protein level Protein evidence (Ezkurdia et al 2014)
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GO:0000139[Golgi membrane] GO:0000166[nucleotide binding] GO:0003924[GTPase activity] GO:0003925[G protein activity] GO:0005515[protein binding] GO:0005525[GTP binding] GO:0005737[cytoplasm] GO:0005789[endoplasmic reticulum membrane] GO:0005813[centrosome] GO:0005815[microtubule organizing center] GO:0005819[spindle] GO:0005829[cytosol] GO:0005856[cytoskeleton] GO:0005886[plasma membrane] GO:0005925[focal adhesion] GO:0006897[endocytosis] GO:0006911[phagocytosis, engulfment] GO:0007015[actin filament organization] GO:0007030[Golgi organization] GO:0007163[establishment or maintenance of cell polarity] GO:0007229[integrin-mediated signaling pathway] GO:0007264[small GTPase mediated signal transduction] GO:0007399[nervous system development] GO:0009653[anatomical structure morphogenesis] GO:0010591[regulation of lamellipodium assembly] GO:0010592[positive regulation of lamellipodium assembly] GO:0016020[membrane] GO:0016567[protein ubiquitination] GO:0016787[hydrolase activity] GO:0017119[Golgi transport complex] GO:0019901[protein kinase binding] GO:0021762[substantia nigra development] GO:0030036[actin cytoskeleton organization] GO:0030154[cell differentiation] GO:0030175[filopodium] GO:0030225[macrophage differentiation] GO:0030307[positive regulation of cell growth] GO:0030335[positive regulation of cell migration] GO:0030425[dendrite] GO:0030496[midbody] GO:0031274[positive regulation of pseudopodium assembly] GO:0031333[negative regulation of protein-containing complex assembly] GO:0031996[thioesterase binding] GO:0032427[GBD domain binding] GO:0032467[positive regulation of cytokinesis] GO:0032488[Cdc42 protein signal transduction] GO:0032991[protein-containing complex] GO:0034191[apolipoprotein A-I receptor binding] GO:0034329[cell junction assembly] GO:0036464[cytoplasmic ribonucleoprotein granule] GO:0038189[neuropilin signaling pathway] GO:0042802[identical protein binding] GO:0042995[cell projection] GO:0043005[neuron projection] GO:0043025[neuronal cell body] GO:0043197[dendritic spine] GO:0043227[membrane-bounded organelle] GO:0044788[modulation by host of viral process] GO:0045198[establishment of epithelial cell apical/basal polarity] GO:0048549[positive regulation of pinocytosis] GO:0051130[positive regulation of cellular component organization] GO:0051233[spindle midzone] GO:0051301[cell division] GO:0051489[regulation of filopodium assembly] GO:0051491[positive regulation of filopodium assembly] GO:0051492[regulation of stress fiber assembly] GO:0051496[positive regulation of stress fiber assembly] GO:0051683[establishment of Golgi localization] GO:0051988[regulation of attachment of spindle microtubules to kinetochore] GO:0060071[Wnt signaling pathway, planar cell polarity pathway] GO:0060997[dendritic spine morphogenesis] GO:0061630[ubiquitin protein ligase activity] GO:0070062[extracellular exosome] GO:0071944[cell periphery] GO:0072384[organelle transport along microtubule] GO:0072686[mitotic spindle] GO:0099563[modification of synaptic structure] GO:1900026[positive regulation of substrate adhesion-dependent cell spreading] GO:2000251[positive regulation of actin cytoskeleton reorganization]
Q5JYX0 [Direct mapping] Cell division control protein 42 homolog A0A024RAA5 [Target identity:100%; Query identity:100%] Cell division control protein 42 homolog
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Predicted intracellular proteins Intracellular proteins predicted by MDM and MDSEC RAS pathway related proteins Protein evidence (Ezkurdia et al 2014)
A0A494BZX6 [Direct mapping] Cell division control protein 42 homolog
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SCAMPI predicted membrane proteins Predicted intracellular proteins Intracellular proteins predicted by MDM and MDSEC RAS pathway related proteins Protein evidence (Ezkurdia et al 2014)
P60953 [Direct mapping] Cell division control protein 42 homolog
Show all
A0A024RAA5 [Target identity:100%; Query identity:100%] Cell division control protein 42 homolog
Show all
Enzymes ENZYME proteins Hydrolases Predicted intracellular proteins Intracellular proteins predicted by MDM and MDSEC Plasma proteins RAS pathway related proteins Disease related genes Potential drug targets Mapped to neXtProt neXtProt - Evidence at protein level Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014)
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GO:0000139[Golgi membrane] GO:0000166[nucleotide binding] GO:0000322[storage vacuole] GO:0003161[cardiac conduction system development] GO:0003253[cardiac neural crest cell migration involved in outflow tract morphogenesis] GO:0003924[GTPase activity] GO:0003925[G protein activity] GO:0005515[protein binding] GO:0005525[GTP binding] GO:0005737[cytoplasm] GO:0005789[endoplasmic reticulum membrane] GO:0005813[centrosome] GO:0005815[microtubule organizing center] GO:0005819[spindle] GO:0005829[cytosol] GO:0005856[cytoskeleton] GO:0005886[plasma membrane] GO:0005911[cell-cell junction] GO:0005925[focal adhesion] GO:0006468[protein phosphorylation] GO:0006897[endocytosis] GO:0006911[phagocytosis, engulfment] GO:0007015[actin filament organization] GO:0007030[Golgi organization] GO:0007088[regulation of mitotic nuclear division] GO:0007097[nuclear migration] GO:0007163[establishment or maintenance of cell polarity] GO:0007229[integrin-mediated signaling pathway] GO:0007264[small GTPase mediated signal transduction] GO:0007399[nervous system development] GO:0008104[protein localization] GO:0009653[anatomical structure morphogenesis] GO:0010591[regulation of lamellipodium assembly] GO:0010592[positive regulation of lamellipodium assembly] GO:0016020[membrane] GO:0016567[protein ubiquitination] GO:0016787[hydrolase activity] GO:0017119[Golgi transport complex] GO:0019901[protein kinase binding] GO:0021762[substantia nigra development] GO:0030036[actin cytoskeleton organization] GO:0030154[cell differentiation] GO:0030175[filopodium] GO:0030225[macrophage differentiation] GO:0030307[positive regulation of cell growth] GO:0030335[positive regulation of cell migration] GO:0030425[dendrite] GO:0030496[midbody] GO:0030742[GTP-dependent protein binding] GO:0031252[cell leading edge] GO:0031256[leading edge membrane] GO:0031274[positive regulation of pseudopodium assembly] GO:0031333[negative regulation of protein-containing complex assembly] GO:0031996[thioesterase binding] GO:0032427[GBD domain binding] GO:0032467[positive regulation of cytokinesis] GO:0032488[Cdc42 protein signal transduction] GO:0032991[protein-containing complex] GO:0034191[apolipoprotein A-I receptor binding] GO:0034329[cell junction assembly] GO:0034332[adherens junction organization] GO:0035050[embryonic heart tube development] GO:0035088[establishment or maintenance of apical/basal cell polarity] GO:0036336[dendritic cell migration] GO:0036464[cytoplasmic ribonucleoprotein granule] GO:0038189[neuropilin signaling pathway] GO:0042802[identical protein binding] GO:0042995[cell projection] GO:0043005[neuron projection] GO:0043025[neuronal cell body] GO:0043197[dendritic spine] GO:0043227[membrane-bounded organelle] GO:0043393[regulation of protein binding] GO:0043410[positive regulation of MAPK cascade] GO:0043552[positive regulation of phosphatidylinositol 3-kinase activity] GO:0044788[modulation by host of viral process] GO:0045177[apical part of cell] GO:0045198[establishment of epithelial cell apical/basal polarity] GO:0045335[phagocytic vesicle] GO:0046847[filopodium assembly] GO:0048549[positive regulation of pinocytosis] GO:0048664[neuron fate determination] GO:0051130[positive regulation of cellular component organization] GO:0051233[spindle midzone] GO:0051301[cell division] GO:0051489[regulation of filopodium assembly] GO:0051491[positive regulation of filopodium assembly] GO:0051492[regulation of stress fiber assembly] GO:0051496[positive regulation of stress fiber assembly] GO:0051647[nucleus localization] GO:0051649[establishment of localization in cell] GO:0051683[establishment of Golgi localization] GO:0051988[regulation of attachment of spindle microtubules to kinetochore] GO:0060047[heart contraction] GO:0060071[Wnt signaling pathway, planar cell polarity pathway] GO:0060501[positive regulation of epithelial cell proliferation involved in lung morphogenesis] GO:0060997[dendritic spine morphogenesis] GO:0061630[ubiquitin protein ligase activity] GO:0070062[extracellular exosome] GO:0071346[cellular response to interferon-gamma] GO:0071944[cell periphery] GO:0072384[organelle transport along microtubule] GO:0072686[mitotic spindle] GO:0086101[endothelin receptor signaling pathway involved in heart process] GO:0098978[glutamatergic synapse] GO:0099175[regulation of postsynapse organization] GO:0099563[modification of synaptic structure] GO:1900026[positive regulation of substrate adhesion-dependent cell spreading] GO:2000251[positive regulation of actin cytoskeleton reorganization]
P60953 [Direct mapping] Cell division control protein 42 homolog
Show all
A0A024RAA5 [Target identity:100%; Query identity:100%] Cell division control protein 42 homolog
Show all
Enzymes ENZYME proteins Hydrolases Predicted intracellular proteins Intracellular proteins predicted by MDM and MDSEC Plasma proteins RAS pathway related proteins Disease related genes Potential drug targets Mapped to neXtProt neXtProt - Evidence at protein level Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000139[Golgi membrane] GO:0000166[nucleotide binding] GO:0003924[GTPase activity] GO:0003925[G protein activity] GO:0005515[protein binding] GO:0005525[GTP binding] GO:0005737[cytoplasm] GO:0005789[endoplasmic reticulum membrane] GO:0005813[centrosome] GO:0005815[microtubule organizing center] GO:0005819[spindle] GO:0005829[cytosol] GO:0005856[cytoskeleton] GO:0005886[plasma membrane] GO:0005925[focal adhesion] GO:0006897[endocytosis] GO:0006911[phagocytosis, engulfment] GO:0007015[actin filament organization] GO:0007030[Golgi organization] GO:0007163[establishment or maintenance of cell polarity] GO:0007229[integrin-mediated signaling pathway] GO:0007264[small GTPase mediated signal transduction] GO:0007399[nervous system development] GO:0009653[anatomical structure morphogenesis] GO:0010591[regulation of lamellipodium assembly] GO:0010592[positive regulation of lamellipodium assembly] GO:0016020[membrane] GO:0016567[protein ubiquitination] GO:0016787[hydrolase activity] GO:0017119[Golgi transport complex] GO:0019901[protein kinase binding] GO:0021762[substantia nigra development] GO:0030036[actin cytoskeleton organization] GO:0030154[cell differentiation] GO:0030175[filopodium] GO:0030225[macrophage differentiation] GO:0030307[positive regulation of cell growth] GO:0030335[positive regulation of cell migration] GO:0030425[dendrite] GO:0030496[midbody] GO:0031274[positive regulation of pseudopodium assembly] GO:0031333[negative regulation of protein-containing complex assembly] GO:0031996[thioesterase binding] GO:0032427[GBD domain binding] GO:0032467[positive regulation of cytokinesis] GO:0032488[Cdc42 protein signal transduction] GO:0032991[protein-containing complex] GO:0034191[apolipoprotein A-I receptor binding] GO:0034329[cell junction assembly] GO:0036464[cytoplasmic ribonucleoprotein granule] GO:0038189[neuropilin signaling pathway] GO:0042802[identical protein binding] GO:0042995[cell projection] GO:0043005[neuron projection] GO:0043025[neuronal cell body] GO:0043197[dendritic spine] GO:0043227[membrane-bounded organelle] GO:0044788[modulation by host of viral process] GO:0045198[establishment of epithelial cell apical/basal polarity] GO:0048549[positive regulation of pinocytosis] GO:0051130[positive regulation of cellular component organization] GO:0051233[spindle midzone] GO:0051301[cell division] GO:0051489[regulation of filopodium assembly] GO:0051491[positive regulation of filopodium assembly] GO:0051492[regulation of stress fiber assembly] GO:0051496[positive regulation of stress fiber assembly] GO:0051683[establishment of Golgi localization] GO:0051988[regulation of attachment of spindle microtubules to kinetochore] GO:0060071[Wnt signaling pathway, planar cell polarity pathway] GO:0060997[dendritic spine morphogenesis] GO:0061630[ubiquitin protein ligase activity] GO:0070062[extracellular exosome] GO:0071944[cell periphery] GO:0072384[organelle transport along microtubule] GO:0072686[mitotic spindle] GO:0099563[modification of synaptic structure] GO:1900026[positive regulation of substrate adhesion-dependent cell spreading] GO:2000251[positive regulation of actin cytoskeleton reorganization]