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The primary data page shows the detailed antibody staining in 76 different cell types for each analyzed antibody. In addition, for each cell type, a knowledge-based annotated protein expression score based on all analyzed antibodies is displayed furthest to the right. The images and annotations can be accessed by clicking on the tissue name or score bar. More information can be found in Assays & Annotation.
The tissues and cell types can be ordered by organ, cell type or alphabetically. If ordered by organ, the tissues are presented in groups according to functional features. If ordered by cell type, the cells are presented in groups related to origin.
This score describes the level of antibody staining observed in the annotated cell types as not detected (n), low (l), medium (m) or high (h). It is based on the staining intensity and fraction of stained cells. The images and annotations can be accessed by clicking on the tissue name or score bar. More information can be found in Assays & Annotation.
Annotated protein expressioni
This score describes a knowledge-based best estimate of the protein expression in the annotated cell types as not detected (n), low (l), medium (m) or high (h). It is a result of stringent evaluation of immunohistochemical staining pattern, RNA data from internal and external sources and available protein/gene characterization data. More information can be found in Assays & Annotation.
Summarizing texts describe the staining pattern for each antibody based on staining intensity, fraction of stained cells and subcellular localization. More information can be found in Assays & Annotation.
HPA031257
Monocyte derived cells including Kupffer and Hofbauer cells as well as subsets of cells in bone marrow and lymphoid tissues displayed strong cytoplasmic positivity. Goblet cells in the intestine showed strong immunoreactivity. Moderate cytoplasmic positivity was observed in renal tubules, trophoblasts and adrenal gland. Remaining normal tissues were weakly stained or negative.
HPA031258
Megakaryocytes, lung macrophages and subsets of cells in lymphoid tissues showed moderate cytoplasmic staining. Remaining normal tissues were negative.
HPA031259
Monocyte derived cells, including Kupffer and Hofbauer cells, as well as a subset of cells in bone marrow and lymphoid tissues exhibited moderate to strong cytoplasmic positivity. Remaining normal tissues were weakly stained or negative.
The Human Protein Atlas project is funded
