Midbody ring

The midbody ring is a circular structure located at the core of the midbody in the cytokinetic bridge. It is a highly dense structure that contains microtubules as well as remnants from the contractile ring. The midbody ring acts as a scaffold for factors involved in the final stages of cytokinesis.

Immunofluorescent staining

The midbody is a transient structure present during the final stages of cytokinesis. The midbody ring can be seen as a circular structure in the bulging region at the center of the midbody that lacks staining of the microtubule marker.

Read more about the proteome of the midbody ring as a substructure of microtubules.

CTTNBP2

Cortactin-binding protein 2 (CTTNBP2), is a regulator of actin filaments that is important for dendritic spine formation and maintenance. It also binds to microtubules and induces microtubule bundle formation.

Midbody ring zoomMidbody ring
Zoom inZoom inZoom inZoom in
Zoom outZoom outZoom outZoom out
Toggle full pageToggle full pageToggle full pageToggle full page
Staining of CTTNBP2 in HeLa ( HPA044654 )