Tissue expression cluster

Expression clustersUMAP1UMAP2
IDi
Main specificityi
Main functioni
# Genesi
Annotation reliabilityi
1 Liver & Kidney Metabolism 234 High
2 Skeletal muscle Striated muscle contraction 177 High
3 Non-specific Unknown function 218 Medium
4 Testis Basic cellular processes 313 Medium
5 Brain & Testis Signal transduction 119 Medium
6 Bone marrow Innate immune response 154 High
7 Adipose tissue Mixed function 320 Medium
8 Ciliated cells Cilium organization 384 High
9 Oligodendrocytes Myelination 457 High
10 Testis Spermatid development 245 High
11 Liver Plasma proteins 103 Low
12 Heart muscle Cardiac muscle contraction 142 Medium
13 Skin Cornification 288 High
14 Skeletal muscle Muscle contraction 231 Medium
15 Pancreas Proteolysis 135 High
16 Non-specific Transcription 690 High
17 Neuronal Synaptic function 188 High
18 Non-specific Ribosome 169 High
19 Non-specific Basic cellular processes 569 Low
20 Testis Spermatogenesis 78 High
21 Testis Unknown function 144 Medium
22 Brain Synaptic signal transduction 245 High
23 Non-specific Cellular respiration 279 High
24 Parathyroid gland Vesicular transport 195 Medium
25 Small intestine Absorption 151 High
26 Adrenal gland Steroid metabolism 87 Medium
27 Squamous epithelium Keratinization 226 Medium
28 Neuronal Transcription 217 Medium
29 Squamous epithelium Innate immune response 159 High
30 Heart muscle Heart development 158 High
31 Liver Plasma proteins 126 High
32 Endocrine & Neural Unknown function 76 Low
33 Brain Neuronal signaling 354 High
34 Non-specific Mixed function 202 Low
35 Non-specific Mitochondria 391 High
36 Lymphoid tissue Cytokine signaling 167 High
37 Liver & Intestine Lipid metabolism 184 Medium
38 Salivary gland Salivary secretion 74 High
39 Retina & Testis Cilium 257 Low
40 Non-specific Transcription 474 High
41 Smooth muscle tissue ECM organization 262 Medium
42 Testis Spermatogenesis 209 High
43 Non-specific Mitochondrial translation 243 Medium
44 Testis Spermatogenesis 384 Medium
45 Intestine Digestion 300 Medium
46 Testis Spermatogenesis 120 Medium
47 Spleen Immune response 210 Medium
48 Stomach Proteolysis 160 Medium
49 Pituitary gland Hormone signaling 60 High
50 Epididymis Male reproductive secretion 185 High
51 Thyroid gland Unknown function 170 Low
52 Kidney Transmembrane transport 206 High
53 Non-specific Glycosylation 194 Medium
54 Non-specific Basic cellular processes 258 Medium
55 Kidney & Intestine Metabolism 179 Low
56 Non-specific Unknown function 137 Medium
57 Lung Lung function 58 Medium
58 Placenta Pregnancy 142 High
59 Fallopian tube Tissue development 51 Medium
60 Choroid plexus Transmembrane transport 207 Medium
61 Brain Neuronal signaling 238 High
62 Connective tissue ECM organization 389 Medium
63 Testis Spermatid development 85 High
64 Neuronal Transcription 381 Low
65 Cerebellum Nervous system development 373 High
66 Non-specific Transcription 492 High
67 Lymphoid tissue & Bone marrow Cell proliferation 184 Medium
68 Non-specific Protein processing 342 Medium
69 Liver Oxidoreductase activity 84 Low
70 Lymphoid tissue Immune response 420 High
71 Thymus Adaptive immune response 106 High
72 Testis & Skeletal muscle Protein ubiquitination 29 Medium
73 Breast Lactation 26 High
74 Spermatids Flagellum assembly 196 Medium
75 Epithelium Extracellular exosomes 176 Low
76 Retina Visual perception 175 High
77 Bone marrow Cell proliferation 370 Medium
78 Testis Transcription 332 Low
79 Non-specific Transcription 215 Medium
80 Non-specific Endocytosis 113 Low
81 Lymphoid tissue & Bone marrow Innate immune response 233 Medium
82 Skin Keratinization 81 High
83 Liver Metabolism 337 High

The interactive UMAP plot displays the 83 gene clusters resulting from Louvain clustering of gene expression across all tissue types. General information about the different clusters regarding annotation and number of included genes is shown upon mouse-over, while clicking on a specific cluster in the table will highlight the selected cluster in the plot and display the general information together with a heatmap of the RNA expression across all tissue types for corresponding genes and a Gene Ontology treemap showing the enrichment of GO-terms in the cluster, where applicable.

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Brain
Male reproductive system
Breast and female reproductive system
Muscle tissues
Connective & Soft tissue
Skin
Bone marrow & Lymphoid tissues
Eye
Endocrine tissues
Respiratory system
Proximal digestive tract
Gastrointestinal tract
Liver & Gallbladder
Pancreas
Kidney & Urinary bladder
Other
Non-Specific