Cell line expression cluster

Expression clustersUMAP1UMAP2
IDi
Main specificityi
Main functioni
# Genesi
Annotation reliabilityi
1 Neuronal Visual perception 227 Medium
2 Mucus-secreting cells Unknown function 94 Medium
3 Rhabdoid Membrane components 129 Low
4 Non-specific Transcription 500 High
5 Rhabdoid Unknown function 423 Medium
6 Leukemia Signal transduction 196 Medium
7 Liver cancer Metabolism 312 Medium
8 Non-specific Basic cellular processes 177 Medium
9 Skin cancer Melanin biosynthesis 199 Medium
10 Ciliated cells Ion channel activity 610 Low
11 Neuronal Sensory perception 177 Low
12 Bone cancer Neuronal signaling 237 Medium
13 Non-specific Mixed function 151 Low
14 Myeloid leukemia Innate immune response 453 High
15 Kidney cancer Membrane components 689 Low
16 Thyroid cancer Neuronal signaling 242 Low
17 Neuroblastoma Neuronal signaling 400 Medium
18 Liver cancer Metabolism 215 High
19 Non-specific Unknown function 130 High
20 Myeloma Immune response 89 Medium
21 Lymphoma Adaptive immune response 117 Low
22 Non-specific mRNA splicing & Cell cycle 414 Medium
23 Non-specific Transcription 236 Medium
24 Non-specific Unknown function 427 Medium
25 Non-specific Ribosome 130 High
26 Non-specific Mitochondria & RNA binding 312 Medium
27 Breast cancer Unknown function 687 Low
28 Non-specific Nuclear processes 266 Medium
29 Non-specific Unknown function 48 High
30 Non-specific Gene expression regulation 362 Medium
31 Non-specific Antiviral immune response 108 Medium
32 Non-specific Cell proliferation 122 Very low
33 Sarcoma Muscle contraction 159 Medium
34 Testis cancer Unknown function 159 Low
35 RS4;11 Unknown function 154 Low
36 Non-specific mRNA processing 220 Medium
37 Non-specific mRNA processing 355 Low
38 Non-specific Transcription 299 High
39 Non-specific Transcription 233 High
40 Non-specific Unknown function 259 High
41 Non-specific Nucleosome assembly 70 Medium
42 Non-specific Unknown function 149 Medium
43 Non-specific Basic cellular processes 232 Medium
44 Connective tissue cells ECM organization 165 Medium
45 Non-specific Nuclear processes 294 Medium
46 Lymphoma Humoral immune response 454 Medium
47 Leukemia Hemostasis 382 Low
48 Adipocytes & Endothelial cells Angiogenesis 112 Medium
49 HMC-1 Innate immune response 136 Medium
50 Lymphoma Unknown function 88 Medium
51 Myeloma Immunoglobulins 676 Medium
52 Non-specific Mitochondria 220 Low
53 Squamous epithelial cells Keratinization 967 Medium
54 Non-specific Transcription 224 Low
55 Lymphoma Immune response 400 Medium
56 Non-specific Sensory perception 262 Low
57 Stomach & Colon cancer Digestion 414 Medium
58 Non-specific Nuclear processes 191 Low
59 Leukemia T-cell receptor 439 Medium
60 Prostate cancer Unknown function 146 High
61 BICR 18 Protein kinases 75 Very low
62 Non-specific Plasma proteins 192 Low
63 Non-specific Protein processing 236 Medium
64 Connective tissue cells ECM organization 527 Medium
65 Non-specific Unknown function 103 Low
66 Non-specific Mitochondria 222 Low
67 Non-specific Unknown function 133 Medium
68 Non-specific Cell cycle regulation 172 Medium
69 Skin cancer ECM organization 288 Medium
70 DU4475 Unknown function 120 Medium
71 Lymphoma Inflammatory response 258 Low
72 Neuronal Signal transduction 444 Low

The interactive UMAP plot displays the 72 gene clusters resulting from Louvain clustering of gene expression across all cell lines. General information about the different clusters regarding annotation and number of included genes is shown upon mouse-over, while clicking on a specific cluster in the table will highlight the selected cluster in the plot and display the general information together with a heatmap of the RNA expression across all cell lines for corresponding genes and a Gene Ontology treemap showing the enrichment of GO-terms in the cluster, where applicable.

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Brain
Male reproductive system
Breast and female reproductive system
Connective & Soft tissue
Skin
Bone marrow & Lymphoid tissues
Endocrine tissues
Gastrointestinal tract
Liver & Gallbladder
Kidney & Urinary bladder
Other
Non-Specific