Brain expression cluster

Expression clustersUMAP1UMAP2
IDi
Main specificityi
Main functioni
# Genesi
Annotation reliabilityi
1 Neurons Mixed function 348 Medium
2 Neurons Nucleosome 199 Medium
3 Choroid plexus Cilium 205 Medium
4 Non-specific mRNA splicing & Cell cycle 198 Low
5 Non-specific Mixed function 50 Low
6 Non-specific Immune response 524 Low
7 Non-specific Ribosome 142 Medium
8 Immune cells Immune response 183 Low
9 Non-specific Receptor signaling 275 Medium
10 Cerebellum Nucleic acid binding 343 Medium
11 White matter Signal transduction 593 Medium
12 Non-specific Vasculature 293 Low
13 Oligodendrocytes Mixed function 308 Low
14 Neurons Synaptic function 515 Medium
15 Non-specific Transcription 490 Medium
16 Non-specific Transcription 188 Medium
17 Choroid plexus Cilium 190 Medium
18 Non-specific Mixed function 61 Low
19 Astrocytes Mixed function 451 Low
20 Macrophages & Microglia Immune response 449 Medium
21 Non-specific Metabolism 571 Low
22 Non-specific Mixed function 56 Low
23 Choroid plexus Mixed function 469 Low
24 Neurons Mixed function 192 Low
25 Non-specific Transcription 477 Low
26 Oligodendrocytes Mixed function 150 Low
27 Non-specific Mixed function 382 Low
28 Oligodendrocytes Mixed function 601 Low
29 Forebrain Mixed function 202 Low
30 White matter Myelination 403 High
31 Non-specific Transcription 461 Medium
32 Cerebral cortex Mixed function 292 Low
33 Neurons Mixed function 268 Low
34 Non-specific Mixed function 433 Low
35 Non-specific DNA binding 251 Low
36 Choroid plexus Mixed function 219 Low
37 Neurons Mixed function 337 Low
38 Sub-cortical Mixed function 321 Low
39 Astrocytes Mixed function 325 Medium
40 Astrocytes Astrocyte-neuron interactions 369 Medium
41 Monoamines Neurotransmitter signalling 231 High
42 Choroid plexus Mitochondria 295 Low
43 Hindbrain Mixed function 178 Medium
44 Non-specific Mixed function 394 Low
45 Non-specific Mixed function 225 Low
46 Brainstem Mixed function 237 Low
47 Endothelial cells Vasculature 221 Medium
48 Non-specific Mixed function 355 Low
49 Hindbrain Mixed function 266 Low
50 Non-specific Nucleic acid binding 273 Low
51 Neurons Mixed function 530 Low
52 Neurons & Synapses Synaptic function 419 Medium
53 Neurons Mixed function 527 Low
54 Immune cells T cell receptor 58 High
55 Non-specific Transcription 445 Low
56 Hypothalamus Neuropeptide signaling 394 High

The interactive UMAP plot displays the 56 gene clusters resulting from Louvain clustering of gene expression across all tissue types. General information about the different clusters regarding annotation and number of included genes is shown upon mouse-over, while clicking on a specific cluster in the table will highlight the selected cluster in the plot and display the general information together with a heatmap of the RNA expression across all tissue types for corresponding genes and a Gene Ontology treemap showing the enrichment of GO-terms in the cluster, where applicable.

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Blood & immune cells
Endocrine cells
Endothelial cells
Glial cells
Neuronal cells
Other
Non-Specific