[{"Gene":"KRTDAP","Gene synonym":["KDAP","UNQ467"],"Ensembl":"ENSG00000188508","Gene description":"Keratinocyte differentiation associated protein","Uniprot":["P60985"],"Chromosome":"19","Position":"35487324-35495558","Protein class":["Plasma proteins","Predicted secreted proteins"],"Biological process":["Differentiation"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"5","RNA tissue specific nTPM":{"skin 1":"5957.2","vagina":"1682.9"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"15","RNA single cell type specific nTPM":{"Suprabasal keratinocytes":"8460.7"},"RNA single nuclei brain specificity":"Cell type enhanced","RNA single nuclei brain distribution":"Detected in some","RNA single nuclei brain specificity score":null,"RNA single nuclei brain specific nTPM":{"choroid plexus epithelial cell":"1.7"},"RNA cancer specificity":"Group enriched","RNA cancer distribution":"Detected in many","RNA cancer specificity score":"4","RNA cancer specific FPKM":{"Head and Neck Squamous Cell Carcinoma (TCGA)":"1407.6","Skin Cuteneous Melanoma (TCGA)":"486.5"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in some","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"17","RNA cell line specific nTPM":{"Esophageal cancer":"42.8","head and neck cancer":"38.2"},"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Region enriched","RNA mouse brain regional distribution":"Detected in single","RNA mouse brain regional specificity score":"6","RNA mouse brain regional specific nTPM":{"white matter":"1.6"},"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA063474"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Secreted in other tissues","Secretome function":"Other","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"15000000","Blood expression cluster":null,"Tissue expression cluster":"Cluster 13: Skin - Cornification","Brain expression cluster":"Cluster 32: Cerebral cortex - Mixed function","Cell line expression cluster":"Cluster 53: Squamous epithelial cells - Keratinization","Single cell expression cluster":"Cluster 59: Suprabasal keratinocytes - Cornification","Interactions":null,"Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA063474":"AB_2685019"},"Cancer prognostics - Bladder Urothelial Carcinoma (TCGA)":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.43e-1"},"Cancer prognostics - Breast Invasive Carcinoma (TCGA)":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.42e-1"},"Cancer prognostics - Breast Invasive Carcinoma (validation)":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.39e-1"},"Cancer prognostics - Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma (TCGA)":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.77e-1"},"Cancer prognostics - Colon Adenocarcinoma (TCGA)":null,"Cancer prognostics - Colon Adenocarcinoma (validation)":null,"Cancer prognostics - Glioblastoma Multiforme (TCGA)":null,"Cancer prognostics - Glioblastoma Multiforme (validation)":null,"Cancer prognostics - Head and Neck Squamous Cell Carcinoma (TCGA)":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.72e-2"},"Cancer prognostics - Kidney Chromophobe (TCGA)":null,"Cancer prognostics - Kidney Renal Clear Cell Carcinoma (TCGA)":null,"Cancer prognostics - Kidney Renal Clear Cell Carcinoma (validation)":null,"Cancer prognostics - Kidney Renal Papillary Cell Carcinoma (TCGA)":null,"Cancer prognostics - Liver Hepatocellular Carcinoma (TCGA)":null,"Cancer prognostics - Liver Hepatocellular Carcinoma (validation)":null,"Cancer prognostics - Lung Adenocarcinoma (TCGA)":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.95e-2"},"Cancer prognostics - Lung Adenocarcinoma (validation)":null,"Cancer prognostics - Lung Squamous Cell Carcinoma (TCGA)":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.92e-2"},"Cancer prognostics - Lung Squamous Cell Carcinoma (validation)":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.76e-1"},"Cancer prognostics - Ovary Serous Cystadenocarcinoma (TCGA)":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.27e-2"},"Cancer prognostics - Ovary Serous Cystadenocarcinoma (validation)":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.56e-1"},"Cancer prognostics - Pancreatic Adenocarcinoma (TCGA)":null,"Cancer prognostics - Pancreatic Adenocarcinoma (validation)":null,"Cancer prognostics - Prostate Adenocarcinoma (TCGA)":null,"Cancer prognostics - Rectum Adenocarcinoma (TCGA)":null,"Cancer prognostics - Rectum Adenocarcinoma (validation)":null,"Cancer prognostics - Skin Cuteneous Melanoma (TCGA)":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.40e-1"},"Cancer prognostics - Stomach Adenocarcinoma (TCGA)":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.65e-2"},"Cancer prognostics - Testicular Germ Cell Tumor (TCGA)":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.14e-1"},"Cancer prognostics - Thyroid Carcinoma (TCGA)":null,"Cancer prognostics - Uterine Corpus Endometrial Carcinoma (TCGA)":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.59e-1"}}]