[{"Gene":"DUSP9","Gene synonym":["MKP-4","MKP4"],"Ensembl":"ENSG00000130829","Gene description":"Dual specificity phosphatase 9","Uniprot":["Q99956"],"Chromosome":"X","Position":"153642492-153651326","Protein class":["Enzymes","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Hydrolase","Protein phosphatase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"12","RNA tissue specific nTPM":{"kidney":"55.4","placenta":"70.2"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"20","RNA single cell type specific nTPM":{"Cytotrophoblasts":"1119.9","Distal tubular cells":"418.0","Syncytiotrophoblasts":"1527.5"},"RNA single nuclei brain specificity":"Cell type enhanced","RNA single nuclei brain distribution":"Detected in many","RNA single nuclei brain specificity score":null,"RNA single nuclei brain specific nTPM":{"hippocampal dentate gyrus":"11.1"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"Liver Hepatocellular Carcinoma (TCGA)":"13.1"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in many","RNA cell line specificity score":"4","RNA cell line specific nTPM":{"Gastric cancer":"21.2","liver cancer":"62.7"},"RNA tissue cell type enrichment":["Kidney - Ascending Loop of Henle cells","Testis - Spermatogonia"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA003336"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Endoplasmic reticulum"],"Secretome location":null,"Secretome function":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 58: Placenta - Pregnancy","Brain expression cluster":"Cluster 51: Neurons - Mixed function","Cell line expression cluster":"Cluster 18: Liver cancer - Metabolism","Single cell expression cluster":"Cluster 24: Cytotrophoblasts - Mitochondria","Interactions":19,"Subcellular main location":["Endoplasmic reticulum"],"Subcellular additional location":null,"Antibody RRID":{"HPA003336":"AB_1078709"},"Cancer prognostics - Bladder Urothelial Carcinoma (TCGA)":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.10e-2"},"Cancer prognostics - Breast Invasive Carcinoma (TCGA)":null,"Cancer prognostics - Breast Invasive Carcinoma (validation)":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.43e-2"},"Cancer prognostics - Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma (TCGA)":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.09e-2"},"Cancer prognostics - Colon Adenocarcinoma (TCGA)":null,"Cancer prognostics - Colon Adenocarcinoma (validation)":null,"Cancer prognostics - Glioblastoma Multiforme (TCGA)":null,"Cancer prognostics - Glioblastoma Multiforme (validation)":null,"Cancer prognostics - Head and Neck Squamous Cell Carcinoma (TCGA)":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.23e-3"},"Cancer prognostics - Kidney Chromophobe (TCGA)":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.97e-2"},"Cancer prognostics - Kidney Renal Clear Cell Carcinoma (TCGA)":null,"Cancer prognostics - Kidney Renal Clear Cell Carcinoma (validation)":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.71e-3"},"Cancer prognostics - Kidney Renal Papillary Cell Carcinoma (TCGA)":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.64e-2"},"Cancer prognostics - Liver Hepatocellular Carcinoma (TCGA)":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.39e-2"},"Cancer prognostics - Liver Hepatocellular Carcinoma (validation)":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.75e-3"},"Cancer prognostics - Lung Adenocarcinoma (TCGA)":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.00e-2"},"Cancer prognostics - Lung Adenocarcinoma (validation)":null,"Cancer prognostics - Lung Squamous Cell Carcinoma (TCGA)":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.45e-2"},"Cancer prognostics - Lung Squamous Cell Carcinoma (validation)":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.09e-4"},"Cancer prognostics - Ovary Serous Cystadenocarcinoma (TCGA)":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.45e-1"},"Cancer prognostics - Ovary Serous Cystadenocarcinoma (validation)":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.65e-1"},"Cancer prognostics - Pancreatic Adenocarcinoma (TCGA)":null,"Cancer prognostics - Pancreatic Adenocarcinoma (validation)":null,"Cancer prognostics - Prostate Adenocarcinoma (TCGA)":null,"Cancer prognostics - Rectum Adenocarcinoma (TCGA)":null,"Cancer prognostics - Rectum Adenocarcinoma (validation)":null,"Cancer prognostics - Skin Cuteneous Melanoma (TCGA)":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.13e-1"},"Cancer prognostics - Stomach Adenocarcinoma (TCGA)":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.69e-2"},"Cancer prognostics - Testicular Germ Cell Tumor (TCGA)":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.94e-1"},"Cancer prognostics - Thyroid Carcinoma (TCGA)":null,"Cancer prognostics - Uterine Corpus Endometrial Carcinoma (TCGA)":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.86e-3"}}]