Gene "Gene synonym" Ensembl "Gene description" Uniprot Chromosome Position "Protein class" "Biological process" "Molecular function" "Disease involvement" Evidence "HPA evidence" "UniProt evidence" "NeXtProt evidence" "RNA tissue specificity" "RNA tissue distribution" "RNA tissue specificity score" "RNA tissue specific nTPM" "RNA single cell type specificity" "RNA single cell type distribution" "RNA single cell type specificity score" "RNA single cell type specific nTPM" "RNA single nuclei brain specificity" "RNA single nuclei brain distribution" "RNA single nuclei brain specificity score" "RNA single nuclei brain specific nTPM" "RNA cancer specificity" "RNA cancer distribution" "RNA cancer specificity score" "RNA cancer specific FPKM" "RNA brain regional specificity" "RNA brain regional distribution" "RNA brain regional specificity score" "RNA brain regional specific nTPM" "RNA blood cell specificity" "RNA blood cell distribution" "RNA blood cell specificity score" "RNA blood cell specific nTPM" "RNA blood lineage specificity" "RNA blood lineage distribution" "RNA blood lineage specificity score" "RNA blood lineage specific nTPM" "RNA cell line specificity" "RNA cell line distribution" "RNA cell line specificity score" "RNA cell line specific nTPM" "RNA tissue cell type enrichment" "RNA mouse brain regional specificity" "RNA mouse brain regional distribution" "RNA mouse brain regional specificity score" "RNA mouse brain regional specific nTPM" "RNA pig brain regional specificity" "RNA pig brain regional distribution" "RNA pig brain regional specificity score" "RNA pig brain regional specific nTPM" Antibody "Reliability (IH)" "Reliability (Mouse Brain)" "Reliability (IF)" "Subcellular location" "Secretome location" "Secretome function" "CCD Protein" "CCD Transcript" "Blood concentration - Conc. blood IM [pg/L]" "Blood concentration - Conc. blood MS [pg/L]" "Blood expression cluster" "Tissue expression cluster" "Brain expression cluster" "Cell line expression cluster" "Single cell expression cluster" Interactions "Subcellular main location" "Subcellular additional location" "Antibody RRID" "Cancer prognostics - Bladder Urothelial Carcinoma (TCGA)" "Cancer prognostics - Breast Invasive Carcinoma (TCGA)" "Cancer prognostics - Breast Invasive Carcinoma (validation)" "Cancer prognostics - Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma (TCGA)" "Cancer prognostics - Colon Adenocarcinoma (TCGA)" "Cancer prognostics - Colon Adenocarcinoma (validation)" "Cancer prognostics - Glioblastoma Multiforme (TCGA)" "Cancer prognostics - Glioblastoma Multiforme (validation)" "Cancer prognostics - Head and Neck Squamous Cell Carcinoma (TCGA)" "Cancer prognostics - Kidney Chromophobe (TCGA)" "Cancer prognostics - Kidney Renal Clear Cell Carcinoma (TCGA)" "Cancer prognostics - Kidney Renal Clear Cell Carcinoma (validation)" "Cancer prognostics - Kidney Renal Papillary Cell Carcinoma (TCGA)" "Cancer prognostics - Liver Hepatocellular Carcinoma (TCGA)" "Cancer prognostics - Liver Hepatocellular Carcinoma (validation)" "Cancer prognostics - Lung Adenocarcinoma (TCGA)" "Cancer prognostics - Lung Adenocarcinoma (validation)" "Cancer prognostics - Lung Squamous Cell Carcinoma (TCGA)" "Cancer prognostics - Lung Squamous Cell Carcinoma (validation)" "Cancer prognostics - Ovary Serous Cystadenocarcinoma (TCGA)" "Cancer prognostics - Ovary Serous Cystadenocarcinoma (validation)" "Cancer prognostics - Pancreatic Adenocarcinoma (TCGA)" "Cancer prognostics - Pancreatic Adenocarcinoma (validation)" "Cancer prognostics - Prostate Adenocarcinoma (TCGA)" "Cancer prognostics - Rectum Adenocarcinoma (TCGA)" "Cancer prognostics - Rectum Adenocarcinoma (validation)" "Cancer prognostics - Skin Cuteneous Melanoma (TCGA)" "Cancer prognostics - Stomach Adenocarcinoma (TCGA)" "Cancer prognostics - Testicular Germ Cell Tumor (TCGA)" "Cancer prognostics - Thyroid Carcinoma (TCGA)" "Cancer prognostics - Uterine Corpus Endometrial Carcinoma (TCGA)" SLC6A4 "5-HTT, HTT, OCD1, SERT1" ENSG00000108576 "Solute carrier family 6 member 4" P31645 17 30194319-30236002 "FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted membrane proteins, Transporters" "Antiport, Neurotransmitter transport, Transport" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 10 "intestine: 39.2;lung: 27.9;placenta: 17.8" "Group enriched" "Detected in many" 10 "Cytotrophoblasts: 119.5;Proximal enterocytes: 100.4;Syncytiotrophoblasts: 95.7" "Cell type enhanced" "Detected in many" "splatter: 6.2" "Cancer enhanced" "Detected in some" "Breast Invasive Carcinoma (TCGA): 3.8" "Group enriched" "Detected in many" 11 "midbrain: 507.8;pons: 183.3" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "colorectal cancer: 2.5;liver cancer: 1.4" "Pancreas - Alpha cells" "Region enriched" "Detected in some" 4 "midbrain: 58.4" "Group enriched" "Detected in some" 8 "midbrain: 51.2;pons: 38.2" "HPA054723, HPA071354, HPA074728" Supported Supported Supported "Golgi apparatus,Vesicles" NA NA "Cluster 25: Small intestine - Absorption" "Cluster 41: Monoamines - Neurotransmitter signalling" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 24: Cytotrophoblasts - Mitochondria" 8 "Golgi apparatus, Vesicles" "HPA054723: , HPA071354: , HPA074728: AB_2686708" "unprognostic (1.35e-1)" "unprognostic (1.72e-1)" "unprognostic (1.81e-1)" "unprognostic (3.47e-1)" "unprognostic (6.77e-2)" "unprognostic (7.90e-4)" "unprognostic (6.60e-2)" "unprognostic (3.68e-2)"