[{"Gene":"FAM83A","Gene synonym":["BJ-TSA-9","MGC14128"],"Ensembl":"ENSG00000147689","Gene description":"Family with sequence similarity 83 member A","Uniprot":["Q86UY5"],"Chromosome":"8","Position":"123178960-123210079","Protein class":["Predicted intracellular proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":["Proto-oncogene"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"4","RNA tissue specific nTPM":{"esophagus":"108.1","vagina":"54.1"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Basal prostatic cells":"31.7","Basal respiratory cells":"68.3","Club cells":"50.6","Ionocytes":"51.9","Squamous epithelial cells":"20.0","Suprabasal keratinocytes":"22.8"},"RNA single nuclei brain specificity":"Low cell type specificity","RNA single nuclei brain distribution":"Detected in some","RNA single nuclei brain specificity score":null,"RNA single nuclei brain specific nTPM":null,"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"Head and Neck Squamous Cell Carcinoma (TCGA)":"121.2"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in some","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"head and neck cancer":"76.6"},"RNA tissue cell type enrichment":["Kidney - Endothelial cells","Lung - Respiratory ciliated cells","Prostate - Urothelial cells"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in single","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA052615"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Cytosol"],"Secretome location":null,"Secretome function":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 29: Squamous epithelium - Innate immune response","Brain expression cluster":"Cluster 48: Non-specific - Mixed function","Cell line expression cluster":"Cluster 53: Squamous epithelial cells - Keratinization","Single cell expression cluster":"Cluster 35: Respiratory epithelial cells - Unknown function","Interactions":23,"Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"HPA052615":"AB_2797244"},"Cancer prognostics - Bladder Urothelial Carcinoma (TCGA)":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.49e-1"},"Cancer prognostics - Breast Invasive Carcinoma (TCGA)":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.64e-2"},"Cancer prognostics - Breast Invasive Carcinoma (validation)":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.02e-2"},"Cancer prognostics - Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma (TCGA)":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.95e-3"},"Cancer prognostics - Colon Adenocarcinoma (TCGA)":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.11e-1"},"Cancer prognostics - Colon Adenocarcinoma (validation)":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.45e-1"},"Cancer prognostics - Glioblastoma Multiforme (TCGA)":null,"Cancer prognostics - Glioblastoma Multiforme (validation)":null,"Cancer prognostics - Head and Neck Squamous Cell Carcinoma (TCGA)":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.11e-1"},"Cancer prognostics - Kidney Chromophobe (TCGA)":null,"Cancer prognostics - Kidney Renal Clear Cell Carcinoma (TCGA)":null,"Cancer prognostics - Kidney Renal Clear Cell Carcinoma (validation)":null,"Cancer prognostics - Kidney Renal Papillary Cell Carcinoma (TCGA)":null,"Cancer prognostics - Liver Hepatocellular Carcinoma (TCGA)":null,"Cancer prognostics - Liver Hepatocellular Carcinoma (validation)":null,"Cancer prognostics - Lung Adenocarcinoma (TCGA)":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.29e-8"},"Cancer prognostics - Lung Adenocarcinoma (validation)":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.81e-4"},"Cancer prognostics - Lung Squamous Cell Carcinoma (TCGA)":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.23e-3"},"Cancer prognostics - Lung Squamous Cell Carcinoma (validation)":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.44e-5"},"Cancer prognostics - Ovary Serous Cystadenocarcinoma (TCGA)":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.71e-2"},"Cancer prognostics - Ovary Serous Cystadenocarcinoma (validation)":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.26e-2"},"Cancer prognostics - Pancreatic Adenocarcinoma (TCGA)":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.55e-6"},"Cancer prognostics - Pancreatic Adenocarcinoma (validation)":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.61e-4"},"Cancer prognostics - Prostate Adenocarcinoma (TCGA)":null,"Cancer prognostics - Rectum Adenocarcinoma (TCGA)":null,"Cancer prognostics - Rectum Adenocarcinoma (validation)":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.03e-1"},"Cancer prognostics - Skin Cuteneous Melanoma (TCGA)":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.34e-1"},"Cancer prognostics - Stomach Adenocarcinoma (TCGA)":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.44e-1"},"Cancer prognostics - Testicular Germ Cell Tumor (TCGA)":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.09e-2"},"Cancer prognostics - Thyroid Carcinoma (TCGA)":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.90e-1"},"Cancer prognostics - Uterine Corpus Endometrial Carcinoma (TCGA)":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.92e-2"}},{"Gene":"RAET1L","Gene synonym":[],"Ensembl":"ENSG00000155918","Gene description":"Retinoic acid early transcript 1L","Uniprot":["Q5VY80"],"Chromosome":"6","Position":"150018334-150025532","Protein class":["Predicted membrane proteins"],"Biological process":["Host-virus interaction","Immunity"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"5","RNA tissue specific nTPM":{"esophagus":"56.4","vagina":"16.7"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Basal keratinocytes":"9.5","Basal respiratory cells":"5.2","Collecting duct cells":"11.7","Squamous epithelial cells":"8.1","Suprabasal keratinocytes":"33.9"},"RNA single nuclei brain specificity":"Not detected","RNA single nuclei brain distribution":"Not detected","RNA single nuclei brain specificity score":null,"RNA single nuclei brain specific nTPM":null,"RNA cancer specificity":"Group enriched","RNA cancer distribution":"Detected in many","RNA cancer specificity score":"5","RNA cancer specific FPKM":{"Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma (TCGA)":"6.6","Head and Neck Squamous Cell Carcinoma (TCGA)":"16.5","Lung Squamous Cell Carcinoma (TCGA)":"12.4"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"cervical cancer":"14.0","Gallbladder cancer":"20.6"},"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA066741"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Vesicles","Plasma membrane"],"Secretome location":null,"Secretome function":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 29: Squamous epithelium - Innate immune response","Brain expression cluster":null,"Cell line expression cluster":"Cluster 53: Squamous epithelial cells - Keratinization","Single cell expression cluster":"Cluster 59: Suprabasal keratinocytes - Cornification","Interactions":2,"Subcellular main location":["Vesicles","Plasma membrane"],"Subcellular additional location":null,"Antibody RRID":{"HPA066741":null},"Cancer prognostics - Bladder Urothelial Carcinoma (TCGA)":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.65e-3"},"Cancer prognostics - Breast Invasive Carcinoma (TCGA)":null,"Cancer prognostics - Breast Invasive Carcinoma (validation)":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.04e-1"},"Cancer prognostics - Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma (TCGA)":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.98e-2"},"Cancer prognostics - Colon Adenocarcinoma (TCGA)":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.79e-1"},"Cancer prognostics - Colon Adenocarcinoma (validation)":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.09e-1"},"Cancer prognostics - Glioblastoma Multiforme (TCGA)":null,"Cancer prognostics - Glioblastoma Multiforme (validation)":null,"Cancer prognostics - Head and Neck Squamous Cell Carcinoma (TCGA)":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.17e-2"},"Cancer prognostics - Kidney Chromophobe (TCGA)":null,"Cancer prognostics - Kidney Renal Clear Cell Carcinoma (TCGA)":null,"Cancer prognostics - Kidney Renal Clear Cell Carcinoma (validation)":null,"Cancer prognostics - Kidney Renal Papillary Cell Carcinoma (TCGA)":null,"Cancer prognostics - Liver Hepatocellular Carcinoma (TCGA)":null,"Cancer prognostics - Liver Hepatocellular Carcinoma (validation)":null,"Cancer prognostics - Lung Adenocarcinoma (TCGA)":null,"Cancer prognostics - Lung Adenocarcinoma (validation)":null,"Cancer prognostics - Lung Squamous Cell Carcinoma (TCGA)":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.70e-2"},"Cancer prognostics - Lung Squamous Cell Carcinoma (validation)":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.39e-1"},"Cancer prognostics - Ovary Serous Cystadenocarcinoma (TCGA)":null,"Cancer prognostics - Ovary Serous Cystadenocarcinoma (validation)":null,"Cancer prognostics - Pancreatic Adenocarcinoma (TCGA)":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.09e-2"},"Cancer prognostics - Pancreatic Adenocarcinoma (validation)":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.77e-2"},"Cancer prognostics - Prostate Adenocarcinoma (TCGA)":null,"Cancer prognostics - Rectum Adenocarcinoma (TCGA)":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.20e-1"},"Cancer prognostics - Rectum Adenocarcinoma (validation)":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.21e-1"},"Cancer prognostics - Skin Cuteneous Melanoma (TCGA)":null,"Cancer prognostics - Stomach Adenocarcinoma (TCGA)":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.41e-1"},"Cancer prognostics - Testicular Germ Cell Tumor (TCGA)":null,"Cancer prognostics - Thyroid Carcinoma (TCGA)":null,"Cancer prognostics - Uterine Corpus Endometrial Carcinoma (TCGA)":null},{"Gene":"S100A14","Gene synonym":["BCMP84","S100A15"],"Ensembl":"ENSG00000189334","Gene description":"S100 calcium binding protein A14","Uniprot":["Q9HCY8"],"Chromosome":"1","Position":"153614255-153616986","Protein class":["Plasma proteins","Predicted intracellular proteins"],"Biological process":["Apoptosis"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"4","RNA tissue specific nTPM":{"esophagus":"3615.1","vagina":"1138.7"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Basal keratinocytes":"2161.5","Distal enterocytes":"1962.1","Proximal enterocytes":"1520.7","Squamous epithelial cells":"3669.3","Suprabasal keratinocytes":"5409.9"},"RNA single nuclei brain specificity":"Cell type enriched","RNA single nuclei brain distribution":"Detected in single","RNA single nuclei brain specificity score":"4","RNA single nuclei brain specific nTPM":{"astrocyte":"2.2"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma (TCGA)":"869.6"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in single","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Gallbladder cancer":"1004.1"},"RNA tissue cell type enrichment":["Colon - Colon enterocytes","Heart muscle - Cardiomyocytes","Lung - Alveolar cells type 2","Minor Salivary Gland - Minor salivary gland basal cells","Prostate - Urothelial cells","Skin - Keratinocyte (other)","Stomach - Gastric mucous cells"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA027613"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nuclear bodies","Plasma membrane","Cell Junctions","Cytosol"],"Secretome location":null,"Secretome function":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"320000","Blood expression cluster":null,"Tissue expression cluster":"Cluster 29: Squamous epithelium - Innate immune response","Brain expression cluster":"Cluster 40: Astrocytes - Astrocyte-neuron interactions","Cell line expression cluster":"Cluster 27: Breast cancer - Unknown function","Single cell expression cluster":"Cluster 59: Suprabasal keratinocytes - Cornification","Interactions":4,"Subcellular main location":["Nuclear bodies","Plasma membrane","Cell Junctions","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA027613":"AB_10602298"},"Cancer prognostics - Bladder Urothelial Carcinoma (TCGA)":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.57e-1"},"Cancer prognostics - Breast Invasive Carcinoma (TCGA)":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.16e-2"},"Cancer prognostics - Breast Invasive Carcinoma (validation)":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.89e-2"},"Cancer prognostics - Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma (TCGA)":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.47e-2"},"Cancer prognostics - Colon Adenocarcinoma (TCGA)":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.56e-1"},"Cancer prognostics - Colon Adenocarcinoma (validation)":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.95e-2"},"Cancer prognostics - Glioblastoma Multiforme (TCGA)":null,"Cancer prognostics - Glioblastoma Multiforme (validation)":null,"Cancer prognostics - Head and Neck Squamous Cell Carcinoma (TCGA)":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.44e-2"},"Cancer prognostics - Kidney Chromophobe (TCGA)":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.98e-2"},"Cancer prognostics - Kidney Renal Clear Cell Carcinoma (TCGA)":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.41e-1"},"Cancer prognostics - Kidney Renal Clear Cell Carcinoma (validation)":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.84e-2"},"Cancer prognostics - Kidney Renal Papillary Cell Carcinoma (TCGA)":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.75e-2"},"Cancer prognostics - Liver Hepatocellular Carcinoma (TCGA)":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.04e-2"},"Cancer prognostics - Liver Hepatocellular Carcinoma (validation)":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.70e-3"},"Cancer prognostics - Lung Adenocarcinoma (TCGA)":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.14e-2"},"Cancer prognostics - Lung Adenocarcinoma (validation)":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.70e-1"},"Cancer prognostics - Lung Squamous Cell Carcinoma (TCGA)":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.48e-1"},"Cancer prognostics - Lung Squamous Cell Carcinoma (validation)":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.05e-5"},"Cancer prognostics - Ovary Serous Cystadenocarcinoma (TCGA)":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.45e-1"},"Cancer prognostics - Ovary Serous Cystadenocarcinoma (validation)":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.97e-1"},"Cancer prognostics - Pancreatic Adenocarcinoma (TCGA)":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.38e-3"},"Cancer prognostics - Pancreatic Adenocarcinoma (validation)":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.17e-2"},"Cancer prognostics - Prostate Adenocarcinoma (TCGA)":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.01e-1"},"Cancer prognostics - Rectum Adenocarcinoma (TCGA)":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.45e-2"},"Cancer prognostics - Rectum Adenocarcinoma (validation)":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.89e-3"},"Cancer prognostics - Skin Cuteneous Melanoma (TCGA)":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.25e-1"},"Cancer prognostics - Stomach Adenocarcinoma (TCGA)":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.70e-2"},"Cancer prognostics - Testicular Germ Cell Tumor (TCGA)":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.85e-1"},"Cancer prognostics - Thyroid Carcinoma (TCGA)":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.28e-2"},"Cancer prognostics - Uterine Corpus Endometrial Carcinoma (TCGA)":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.15e-2"}}]