Pancreatic cancer

The upper left dot plot(s) shows the consistency between the cancer type related cell lines and their corresponding TCGA disease cohort based on Spearman correlation and normalized enrichment score (NES). In the lower left is a list of the cell lines ranked according to their similarity to the cancer type. By clicking on a cell line in the dot plot or in the ranked list lollipop plots showing the activity of cancer-related pathways inferred using PROGENy and CytoSig cytokines for that particular cell line will be displayed. For more details about the analysis see Methods summary and information about all cell lines can be found here.

Pancreatic Adenocarcinoma (PAAD)

Explore the disease cohort in TCGA

Capan-1Panc 05.04CFPAC-1HuP-T4HPAF-IITCC-Pan2AsPC-1SU.86.86PaTu 8988sYAPCBxPC-3SUIT-2Panc 04.03CAPAN-2PK-59SNU-213Panc 03.27Panc 08.13HPACPanc 02.13PSN1HuP-T3QGP-1Hs 766TPanc 02.03KCI-MOH1SW1990SNU-410DAN-GL3.3KP-3KP-2PK-8KLM-1PK-45HT3M-4PK-1SNU-324PK-45PPanc 10.05PANC-1PaTu 8902MIA PaCa-2KP-4PL45PaTu 8988t0.720.740.76Spearman's ฯ11.5NES
Ranking
Cell line
Corr
NES
1 Capan-1 0.78 1.99
2 Panc 05.04 0.77 1.9
3 CFPAC-1 0.78 1.8
4 HuP-T4 0.77 1.87
4 HPAF-II 0.77 1.85
6 TCC-Pan2 0.77 1.76
7 AsPC-1 0.76 1.82
7 SU.86.86 0.76 1.76
9 PaTu 8988s 0.76 1.9
10 YAPC 0.77 1.66
11 BxPC-3 0.76 1.72
12 SUIT-2 0.75 1.74
12 Panc 04.03 0.76 1.58
14 CAPAN-2 0.76 1.53
15 PK-59 0.75 1.68
16 SNU-213 0.76 1.46
17 Panc 03.27 0.76 1.38
17 Panc 08.13 0.75 1.58
19 HPAC 0.74 1.72
20 Panc 02.13 0.75 1.46
21 PSN1 0.73 1.73
22 HuP-T3 0.75 1.51
23 QGP-1 0.71 1.95
24 Hs 766T 0.74 1.48
25 Panc 02.03 0.75 1.24
26 KCI-MOH1 0.73 1.66
27 SW1990 0.75 1.23
27 SNU-410 0.74 1.26
29 DAN-G 0.74 1.42
30 L3.3 0.73 1.5
31 KP-3 0.73 1.58
32 KP-2 0.74 1.16
33 PK-8 0.73 1.26
34 KLM-1 0.74 1.06
34 PK-45H 0.74 1.21
34 T3M-4 0.73 1.35
37 PK-1 0.73 1.08
38 SNU-324 0.74 0.79
39 PK-45P 0.73 1.07
40 Panc 10.05 0.73 0.86
41 PANC-1 0.72 0.96
42 PaTu 8902 0.72 0.81
42 MIA PaCa-2 0.7 0.94
42 KP-4 0.71 0.92
45 PL45 0.72 0.71
46 PaTu 8988t 0.7 0.86
CELL LINE DATA
Cell line Capan-1
Patient: Male, 40
Disease subtype: Ductal Adenocarcinoma, exocrine
Primary/metastasis: Metastasis
Sample collection site: Liver
Cellosaurus: CVCL_0237
PROGENy
AndrogenEGFREstrogenHypoxiaJAK-STATMAPKNFkBp53PI3KTGFbTNFaTrailVEGFWNTNES-2-1012Z-scoreSignificant - upregulatedSignificant - downregulatedNon significant
CytoSig
Activin ABDNFBMP2BMP4BMP6CD40LCXCL12EGFFGF2GCSFGDF11GMCSFHGFIFN1IFNGIFNLIL10IL12IL13IL15IL17AIL1AIL1BIL2IL21IL22IL27IL3IL36IL4IL6LIFLTAMCSFNOOSMTGFB1TGFB3TNFATRAILTWEAKVEGFAWNT3ANES-10-50510Z-score