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On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.
Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.
If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.
h
m
l
n
Glial cells:
Not detected
Neuronal cells:
Not detected
RNA expressioni
A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.
The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.
Scroll down to view mRNA expression data in more detail.
Consensus:
7.3
nTPM
HPA Brain:
53.4
nTPM
GTEx:
7.3
nTPM
HIPPOCAMPUS - Antibody stainingi
Antibody staining in the annotated cell types in the current human tissue is reported as not detected, low, medium, or high, based on conventional immunohistochemistry profiling in selected tissues. This score is based on the combination of the staining intensity and fraction of stained cells.
Each image is clickable and will lead to virtual microscopy that enables deeper exploration of all samples and also displays staining intensity scores, fraction scores and subcellular localization as well as patient and tissue information for each sample.
Antibody CAB004669
Glial cells
Medium
Neuronal cells
High
HIPPOCAMPAL FORMATION - HPA Brain RNA-seq
Max subtype nTPMi
Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.
53.4
Sample id
Sample description
nTPM
Hippocampus nTPM: 52.8
2148
Female, age 91, left hemisphere
69.1
1911
Female, age 85, right hemisphere
60.5
2529
Female, age 94, left hemisphere
58.0
1855
Male, age 76, left hemisphere
47.8
2621
Female, age 67, right hemisphere
43.2
1898
Male, age 80, left hemisphere
38.2
Dentate gyrus nTPM: 49.6
1927
Female, age 91, both hemispheres
62.4
2528
Male, age 74, both hemispheres
58.5
2246
Female, age 85, both hemispheres
56.0
2010
Male, age 76, both hemispheres
45.3
2530
Female, age 94, left hemisphere
41.2
2531
Female, age 67, both hemispheres
34.0
Entorhinal gyrus nTPM: 41.0
2117
Female, age 91, right hemisphere
63.3
1787
Male, age 76, left hemisphere
40.5
1938
Female, age 85, left hemisphere
40.2
2686
Male, age 75, right hemisphere
39.4
2613
Female, age 94, left hemisphere
32.7
2764
Male, age 80, right hemisphere
29.7
Hippocampus, CA1 nTPM: 53.4
1873
Female, age 85, both hemispheres
65.0
2082
Female, age 91, right hemisphere
56.6
2527
Male, age 74, both hemispheres
54.4
2045
Male, age 76, both hemispheres
49.3
2749
Male, age 80, left hemisphere
41.6
Hippocampus, CA2 nTPM: 46.9
2113
Female, age 91, right hemisphere
62.6
1940
Female, age 85, left hemisphere
54.0
2249
Male, age 74, both hemispheres
49.4
1963
Male, age 80, left hemisphere
42.9
2437
Female, age 94, left hemisphere
39.8
1892
Male, age 76, both hemispheres
32.7
Hippocampus, CA3 nTPM: 46.3
2436
Male, age 74, both hemispheres
59.2
1891
Female, age 85, both hemispheres
58.3
2861
Female, age 67, both hemispheres
45.4
1867
Male, age 76, both hemispheres
41.0
2620
Female, age 94, left hemisphere
39.0
2137
Male, age 80, left hemisphere
34.9
Parahippocampal cortex nTPM: 41.5
2692
Male, age 74, both hemispheres
57.9
1990
Female, age 91, right hemisphere
44.8
2622
Female, age 67, right hemisphere
44.6
1933
Female, age 85, both hemispheres
42.5
2245
Female, age 91, both hemispheres
41.7
2693
Female, age 94, both hemispheres
40.1
2018
Male, age 76, both hemispheres
39.2
2250
Female, age 67, right hemisphere
39.0
1850
Male, age 80, both hemispheres
34.2
2532
Female, age 72, left hemisphere
31.1
Perirhinal gyrus nTPM: 34.9
2521
Female, age 94, right hemisphere
41.4
1841
Female, age 85, right hemisphere
38.0
1847
Female, age 91, left hemisphere
37.1
1794
Male, age 80, right hemisphere
30.0
2848
Male, age 76, right hemisphere
28.0
Subiculum nTPM: 47.5
2729
Female, age 91, right hemisphere
70.2
2619
Male, age 74, both hemispheres
54.0
2438
Female, age 94, left hemisphere
48.3
2042
Male, age 76, both hemispheres
40.6
1977
Female, age 85, both hemispheres
36.2
1901
Male, age 80, both hemispheres
35.4
HIPPOCAMPAL FORMATION - GTEx RNA-seqi
RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.
Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi
Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.
7.3
GTEx sample id
Sample description
nTPM
Brain - Hippocampus Average nTPM: 7.3
Samples: 197
Max nTPM: 16.1
Min nTPM: 2.0
Std nTPM: 2.5
Median nTPM: 6.9
The Human Protein Atlas project is funded
