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The Survival Scatter plot shows the clinical status (i.e. dead or alive) for all individuals in the patient cohort, based on the same data that underlies the corresponding Kaplan-Meier plots. Patients that are alive at last time for follow-up are shown in blue and patients who have died during the study are shown in red.
The x-axis shows the expression levels (FPKM) of the investigated gene in the tumor tissue at the time of diagnosis. The y-axis shows the follow-up time after diagnosis (years). Both axes are complimented with kernel density curves demonstrating the data density over the axes. The top density plot shows the expression levels (FPKM) distribution among dead (red) and alive patients (blue). The right density plot shows the data density of the survived years of dead patients with high and low expression levels respectively, stratified using the cutoff indicated by the vertical dashed line through the Survival Scatter plot. This cutoff is automatically defined based on the FPKM cutoff that minimizes the p-score. The cutoff can be changed by dragging the vertical line or by entering a cutoff value in the square labeled "Current cut-off".
Under the Survival Scatter plot the p-score landscape (black curve; left axis) is shown together with dead median separation (red curve; right axis). Dead median separation is the difference in median mRNA expression between patients who have died with high and low expression, respectively. It is calculated as follows: median FPKM expression of dead patients with high expression - median FPKM expression of dead patients with low expression. This is intended to aid the user in visually exploring custom cutoffs and the associated p-scores and dead median separation.
Individual patient data is displayed and can be filtered by clicking on one or more of the category buttons on the top of the page. Categories describing expression level and patient information include: high, low, alive, dead, female, male and tumor stages. The scale of the x-axis can be toggled between linear and log-scale by clicking on the "x log" button. Mouse-over function shows TCGA ID, patient information and mRNA expression (FPKM) for each patient.
& Survival analysisi
Kaplan-Meier plots summarize results from analysis of correlation between mRNA expression level and patient survival. Patients were divided based on level of expression into one of the two groups "low" (under cut off) or "high" (over cut off). X-axis shows time for survival (years) and y-axis shows the probability of survival, where 1.0 corresponds to 100 percent.
BACE2 is not prognostic in Liver Hepatocellular Carcinoma (TCGA)
Stage:
Survival analysis
Current cut offi
Current cut-off shows the cut-off (FPKM) currently selected. It may be changed manually. When the current cut-off is changed, the vertical dashed line indicating cut-off, the interactive survival scatter plot and the Kaplan-Meier curve will be automatically adjusted to show results accordingly.
:
Best expression cut offi
Based on the FPKM value of each gene, patients were classified into two groups and association between prognosis (survival) and gene expression (FPKM) was examined. The best expression cut-off refers the FPKM value that yields maximal difference with regard to survival between the two groups at the lowest log-rank P-value. Best expression cut-off was selected based on survival analysis .
When clicking on this number, the vertical dashed line indicating cut-off, the interactive survival plot, and the Kaplan-Meier curve will be adjusted to show results based on the best expression cut-off.
Median expression refers to the median FPKM value calculated based on the gene expression (FPKM) data from all patients in this dataset. When clicking on this number, the vertical dashed line indicating cut-off, the interactive survival plot, and the Kaplan-Meier curve will be adjusted to show results based on the median expression.
Median follow up time refers to the median time (years) after diagnosis with this type of cancer, based on clinical data from all patients in this dataset.
: 1.63
P scorei
Log-rank P value for Kaplan-Meier plot showing results from analysis of correlation between mRNA expression level and patient survival.
0.010
5-year survival highi
5-year survival for patients with higher expression than the expression cutoff.
For melanoma and glioma, 3-year survival is shown.
35%
5-year survival lowi
5-year survival for patients with lower expression than the expression cutoff.
For melanoma and glioma, 3-year survival is shown.
52%
TCGA RNA samplesi
RNA-seq data is reported as average FPKM (number Fragments Per Kilobase of exon per Million reads), generated by the The Cancer Genome Atlas (TCGA) .
Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. FPKM values of the individual samples are presented next to the box plot.
Average TPM
2.1
Number of samples
362
Samples
Sample
Description
TPM
TCGA-DD-A4NA-01A
0 years, female, white, stage:Stage IIIC, alive, 1008 days
76.0
TCGA-CC-5263-01A
0 years, male, asian, stage:Stage IIIA, dead, 129 days
53.6
TCGA-FV-A3I0-01A
0 years, female, white, stage:Stage II, alive, 848 days
35.0
TCGA-2Y-A9H2-01A
0 years, female, white, stage:Stage I, alive, 1731 days
32.9
TCGA-ED-A7PX-01A
0 years, female, asian, stage:Stage II, alive, 6 days
28.8
TCGA-ED-A82E-01A
0 years, female, asian, stage:Stage IIIA, alive, 408 days
24.8
TCGA-ZP-A9D2-01A
0 years, male, white, stage:'--, dead, 765 days
23.2
TCGA-DD-A4NQ-01A
0 years, male, white, stage:Stage II, dead, 373 days
20.6
TCGA-CC-A1HT-01A
0 years, male, asian, stage:Stage IIIA, dead, 101 days
17.7
TCGA-DD-AA3A-01A
0 years, female, white, stage:Stage I, dead, 410 days
16.0
TCGA-K7-AAU7-01A
0 years, male, white, stage:Stage II, alive, 359 days
15.9
TCGA-CC-5260-01A
0 years, female, asian, stage:Stage IIIC, dead, 87 days
13.3
TCGA-DD-AACH-01A
0 years, male, asian, stage:Stage II, dead, 195 days
12.0
TCGA-UB-A7MA-01A
0 years, female, white, stage:Stage II, alive, 848 days
11.0
TCGA-BC-A112-01A
0 years, male, white, stage:'--, dead, 153 days
10.7
TCGA-DD-AAD5-01A
0 years, male, asian, stage:Stage I, alive, 1345 days
9.6
TCGA-CC-5264-01A
0 years, male, asian, stage:Stage IIIA, dead, 102 days
9.4
TCGA-BC-A217-01A
0 years, female, white, stage:Stage II, dead, 1397 days
9.3
TCGA-DD-AACY-01A
0 years, male, asian, stage:Stage I, alive, 1450 days
9.3
TCGA-ED-A97K-01A
0 years, male, asian, stage:Stage IIIA, alive, 6 days
9.0
TCGA-RC-A6M5-01A
0 years, female, white, stage:Stage IVA, alive, 15 days
8.9
TCGA-MR-A8JO-01A
0 years, male, white, stage:Stage I, alive, 330 days
8.9
TCGA-CC-A3MA-01A
0 years, male, asian, stage:Stage IIIA, dead, 303 days
8.7
TCGA-ED-A7PZ-01A
0 years, male, asian, stage:Stage II, alive, 6 days
8.5
TCGA-G3-AAV7-01A
0 years, male, asian, stage:Stage II, alive, 361 days
7.9
TCGA-BC-A10U-01A
0 years, male, white, stage:'--, dead, 837 days
7.6
TCGA-2Y-A9GW-01A
0 years, male, white, stage:Stage I, dead, 1271 days
7.5
TCGA-BC-A10Q-01A
0 years, female, white, stage:'--, dead, 1135 days
6.9
TCGA-DD-A1EA-01A
0 years, male, asian, stage:Stage II, alive, 2415 days
6.5
TCGA-DD-A114-01A
0 years, male, black or african american, stage:Stage II, dead, 1149 days
6.4
TCGA-DD-A118-01A
0 years, female, white, stage:Stage II, alive, 3437 days
5.8
TCGA-ED-A7XP-01A
0 years, female, asian, stage:Stage II, alive, 400 days
5.7
TCGA-BC-A10R-01A
0 years, female, white, stage:'--, dead, 308 days
5.4
TCGA-CC-A7IJ-01A
0 years, male, asian, stage:Stage II, alive, 382 days
4.4
TCGA-ED-A66X-01A
0 years, male, asian, stage:Stage IIIA, alive, 406 days
4.4
TCGA-DD-AACT-01A
0 years, female, asian, stage:Stage I, alive, 1562 days
4.1
TCGA-DD-A1EK-01A
0 years, female, white, stage:Stage IVB, dead, 558 days
3.9
TCGA-G3-A5SJ-01A
0 years, male, white, stage:Stage I, alive, 698 days
3.9
TCGA-2Y-A9HA-01A
0 years, male, white, stage:Stage II, dead, 36 days
3.8
TCGA-BD-A3EP-01A
0 years, female, black or african american, stage:Stage I, alive, 409 days
3.8
TCGA-CC-5262-01A
0 years, male, asian, stage:Stage IIIC, dead, 103 days
3.6
TCGA-ED-A627-01A
0 years, male, white, stage:Stage I, alive, 423 days
3.6
TCGA-DD-A4NR-01A
0 years, female, white, stage:Stage I, dead, 9 days
3.6
TCGA-DD-A39Y-01A
0 years, male, asian, stage:Stage I, dead, 171 days
3.5
TCGA-PD-A5DF-01A
0 years, female, white, stage:Stage IIIB, dead, 639 days
3.4
TCGA-DD-AADW-01A
0 years, male, asian, stage:Stage I, alive, 587 days
3.4
TCGA-BC-A8YO-01A
0 years, female, white, stage:Stage IIIC, alive, 562 days
3.3
TCGA-LG-A6GG-01A
0 years, female, white, stage:Stage II, alive, 387 days
3.3
TCGA-GJ-A9DB-01A
0 years, male, white, stage:Stage I, dead, 67 days
3.0
TCGA-MR-A520-01A
0 years, male, white, stage:Stage I, alive, 229 days
3.0
TCGA-DD-A4NE-01A
0 years, female, white, stage:Stage IIIA, dead, 660 days
2.9
TCGA-RC-A7SB-01A
0 years, male, asian, stage:Stage II, alive, 588 days
2.8
TCGA-DD-A4NL-01A
0 years, male, white, stage:Stage I, alive, 1711 days
2.8
TCGA-T1-A6J8-01A
0 years, male, white, stage:'--, alive, 23 days
2.8
TCGA-DD-A1ED-01A
0 years, male, white, stage:Stage I, alive, 2301 days
2.8
TCGA-EP-A3JL-01A
0 years, male, white, stage:Stage I, alive, 303 days
2.8
TCGA-DD-AAEG-01A
0 years, female, asian, stage:Stage I, alive, 719 days
2.7
TCGA-DD-A4NS-01A
0 years, female, white, stage:Stage I, dead, 2456 days
2.7
TCGA-CC-A8HT-01A
0 years, male, asian, stage:Stage IIIA, dead, 140 days
2.6
TCGA-5C-A9VH-01A
0 years, male, white, stage:Stage I, alive, 322 days
2.6
TCGA-ED-A5KG-01A
0 years, female, asian, stage:Stage II, alive, 854 days
2.6
TCGA-BW-A5NO-01A
0 years, male, black or african american, stage:Stage IIIA, alive, 20 days
2.5
TCGA-G3-A3CI-01A
0 years, male, white, stage:Stage I, alive, 180 days
2.4
TCGA-ZP-A9D1-01A
0 years, female, white, stage:'--, alive, 21 days
2.4
TCGA-DD-A4NH-01A
0 years, female, white, stage:Stage IIIB, alive, 917 days
2.3
TCGA-ED-A4XI-01A
0 years, male, asian, stage:Stage II, alive, 819 days
2.2
TCGA-4R-AA8I-01A
0 years, male, white, stage:Stage II, dead, 262 days
2.2
TCGA-DD-A1EG-01A
0 years, male, white, stage:Stage I, dead, 1372 days
2.1
TCGA-CC-5259-01A
0 years, female, asian, stage:Stage IIIC, alive, 250 days
2.1
TCGA-WX-AA47-01A
0 years, female, white, stage:Stage IIIA, dead, 556 days
2.0
TCGA-DD-AAC8-01A
0 years, male, asian, stage:Stage I, dead, 16 days
2.0
TCGA-DD-AAVW-01A
0 years, male, asian, stage:Stage I, alive, 2317 days
2.0
TCGA-DD-AAD1-01A
0 years, female, asian, stage:Stage I, alive, 564 days
1.9
TCGA-DD-AADK-01A
0 years, female, asian, stage:Stage II, alive, 1049 days
1.7
TCGA-G3-A25Y-01A
0 years, female, asian, stage:Stage I, dead, 452 days
1.7
TCGA-K7-A5RF-01A
0 years, male, white, stage:Stage I, alive, 631 days
1.7
TCGA-CC-A3M9-01A
0 years, male, asian, stage:Stage IIIA, dead, 300 days
1.6
TCGA-2Y-A9H5-01A
0 years, female, white, stage:Stage I, dead, 555 days
1.5
TCGA-CC-5261-01A
0 years, male, asian, stage:Stage II, dead, 97 days
1.5
TCGA-KR-A7K7-01A
0 years, female, white, stage:Stage II, alive, 951 days
1.5
TCGA-DD-A39X-01A
0 years, female, white, stage:Stage I, dead, 1694 days
1.4
TCGA-2Y-A9H0-01A
0 years, male, white, stage:Stage IIIA, alive, 3675 days
1.4
TCGA-DD-AAW0-01A
0 years, male, asian, stage:Stage I, alive, 2015 days
1.4
TCGA-DD-A3A6-01A
0 years, female, white, stage:Stage II, dead, 3258 days
1.4
TCGA-RC-A7SH-01A
0 years, male, asian, stage:Stage II, alive, 468 days
1.4
TCGA-5R-AA1D-01A
0 years, female, white, stage:Stage IIIA, alive, 449 days
1.4
TCGA-ZP-A9D0-01A
0 years, female, black or african american, stage:'--, alive, 1091 days
1.3
TCGA-FV-A3R3-01A
0 years, female, white, stage:Stage I, dead, 366 days
1.3
TCGA-UB-AA0V-01A
0 years, female, white, stage:Stage I, alive, 314 days
1.3
TCGA-XR-A8TC-01A
0 years, female, white, stage:Stage I, alive, 1339 days
1.3
TCGA-2Y-A9GX-01A
0 years, male, white, stage:Stage I, alive, 2442 days
1.3
TCGA-GJ-A3OU-01A
0 years, male, white, stage:Stage I, alive, 879 days
1.3
TCGA-DD-A4ND-01A
0 years, female, white, stage:Stage I, alive, 2746 days
1.3
TCGA-G3-A7M9-01A
0 years, male, white, stage:Stage IIIB, dead, 56 days
1.2
TCGA-DD-A113-01A
0 years, female, white, stage:Stage II, alive, 2425 days
1.2
TCGA-5R-AAAM-01A
0 years, female, white, stage:Stage II, dead, 46 days
1.2
TCGA-BC-A10X-01A
0 years, female, white, stage:Stage IIIA, dead, 770 days
1.2
TCGA-ES-A2HT-01A
0 years, male, black or african american, stage:Stage I, dead, 438 days
1.1
TCGA-G3-A25T-01A
0 years, female, white, stage:Stage IIIA, alive, 1553 days
1.1
TCGA-DD-A4NB-01A
0 years, male, white, stage:Stage I, alive, 989 days
1.1
TCGA-XR-A8TD-01A
0 years, female, white, stage:Stage IIIB, alive, 1030 days
1.1
TCGA-UB-A7MD-01A
0 years, male, black or african american, stage:Stage I, dead, 52 days
1.0
TCGA-DD-AADD-01A
0 years, male, asian, stage:Stage I, alive, 1231 days
1.0
TCGA-2Y-A9GS-01A
0 years, male, white, stage:'--, dead, 724 days
1.0
TCGA-GJ-A6C0-01A
0 years, female, white, stage:Stage II, dead, 31 days
1.0
TCGA-DD-A1EC-01A
0 years, female, white, stage:Stage I, alive, 602 days
1.0
TCGA-ED-A8O6-01A
0 years, female, asian, stage:Stage IIIA, dead, 56 days
1.0
TCGA-DD-A115-01A
0 years, male, white, stage:Stage IIIA, dead, 2542 days
1.0
TCGA-LG-A9QD-01A
0 years, male, white, stage:Stage IIIA, alive, 366 days
0.9
TCGA-CC-A3MC-01A
0 years, male, asian, stage:Stage IIIA, alive, 363 days
0.9
TCGA-BC-A110-01A
0 years, female, black or african american, stage:'--, dead, 2116 days
0.9
TCGA-DD-AAE0-01A
0 years, female, asian, stage:Stage IIIA, alive, 555 days
0.9
TCGA-YA-A8S7-01A
0 years, male, white, stage:Stage IIIA, dead, 412 days
0.9
TCGA-DD-AADC-01A
0 years, male, asian, stage:Stage I, dead, 425 days
0.9
TCGA-5C-AAPD-01A
0 years, male, asian, stage:Stage II, alive, 20 days
0.8
TCGA-CC-A8HV-01A
0 years, female, asian, stage:Stage II, dead, 279 days
0.8
TCGA-MI-A75E-01A
0 years, male, white, stage:Stage IIIC, alive, 507 days
0.8
TCGA-5C-A9VG-01A
0 years, male, white, stage:Stage II, alive, 328 days
0.8
TCGA-DD-A1EH-01A
0 years, male, white, stage:Stage III, alive, 1495 days
0.8
TCGA-WX-AA44-01A
0 years, female, white, stage:Stage I, alive, 615 days
0.7
TCGA-DD-AAD3-01A
0 years, male, asian, stage:Stage I, alive, 1295 days
0.7
TCGA-DD-A1EI-01A
0 years, male, asian, stage:Stage I, alive, 183 days
0.7
TCGA-G3-A3CG-01A
0 years, male, white, stage:Stage I, alive, 673 days
0.7
TCGA-G3-A5SI-01A
0 years, male, asian, stage:Stage II, dead, 768 days
0.7
TCGA-DD-AACN-01A
0 years, male, asian, stage:Stage I, alive, 1302 days
0.7
TCGA-DD-A4NV-01A
0 years, male, white, stage:Stage IIIA, alive, 2398 days
0.7
TCGA-G3-A25X-01A
0 years, male, asian, stage:Stage II, alive, 1779 days
0.6
TCGA-2Y-A9H9-01A
0 years, male, white, stage:Stage I, alive, 697 days
0.6
TCGA-DD-AAVZ-01A
0 years, male, asian, stage:Stage I, alive, 1900 days
0.6
TCGA-2Y-A9H6-01A
0 years, female, white, stage:Stage I, alive, 357 days
0.6
TCGA-DD-AAD2-01A
0 years, male, asian, stage:Stage I, alive, 658 days
0.6
TCGA-DD-AADV-01A
0 years, male, asian, stage:Stage I, alive, 574 days
0.6
TCGA-DD-A1EF-01A
0 years, female, white, stage:Stage I, dead, 394 days
0.6
TCGA-DD-A11D-01A
0 years, female, white, stage:Stage I, dead, 1560 days
0.6
TCGA-ZP-A9CZ-01A
0 years, male, asian, stage:'--, alive, 706 days
0.6
TCGA-DD-AAVQ-01A
0 years, male, asian, stage:Stage I, alive, 2728 days
0.5
TCGA-DD-AACL-01A
0 years, female, asian, stage:Stage I, dead, 107 days
0.5
TCGA-DD-A11C-01A
0 years, male, white, stage:Stage I, alive, 662 days
0.5
TCGA-DD-AACB-01A
0 years, female, asian, stage:Stage I, alive, 2324 days
0.5
TCGA-BC-A10T-01A
0 years, male, white, stage:'--, dead, 837 days
0.5
TCGA-BC-A10W-01A
0 years, male, asian, stage:'--, dead, 91 days
0.5
TCGA-ED-A7XO-01A
0 years, male, asian, stage:Stage IIIA, alive, 427 days
0.5
TCGA-BC-A10S-01A
0 years, male, white, stage:'--, dead, 1423 days
0.5
TCGA-G3-A3CH-01A
0 years, male, asian, stage:Stage IIIA, alive, 780 days
0.5
TCGA-CC-5258-01A
0 years, male, asian, stage:Stage II, dead, 129 days
0.5
TCGA-BC-A216-01A
0 years, female, white, stage:Stage IIIA, alive, 1351 days
0.5
TCGA-DD-A4NJ-01A
0 years, female, white, stage:Stage II, alive, 928 days
0.4
TCGA-G3-A7M6-01A
0 years, female, white, stage:Stage I, alive, 632 days
0.4
TCGA-HP-A5N0-01A
0 years, female, stage:'--, dead, 752 days
0.4
TCGA-2Y-A9GU-01A
0 years, female, white, stage:Stage I, alive, 1939 days
0.4
TCGA-DD-AAVV-01A
0 years, male, asian, stage:Stage II, alive, 2455 days
0.4
TCGA-HP-A5MZ-01A
0 years, male, stage:Stage I, dead, 91 days
0.4
TCGA-CC-A5UC-01A
0 years, male, asian, stage:Stage IIIA, dead, 347 days
0.4
TCGA-K7-A5RG-01A
0 years, male, black or african american, stage:Stage I, alive, 519 days
0.4
TCGA-BC-A69H-01A
0 years, male, white, stage:Stage II, alive, 444 days
0.4
TCGA-CC-A7IE-01A
0 years, male, asian, stage:Stage IIIA, dead, 217 days
0.4
TCGA-DD-AADP-01A
0 years, male, asian, stage:Stage I, alive, 458 days
0.4
TCGA-CC-A7II-01A
0 years, male, asian, stage:Stage IIIA, alive, 399 days
0.4
TCGA-FV-A495-01A
0 years, female, white, stage:Stage II, alive, 1 days
0.4
TCGA-ED-A66Y-01A
0 years, female, asian, stage:Stage IIIA, dead, 296 days
0.4
TCGA-WQ-AB4B-01A
0 years, male, white, stage:Stage II, alive, 395 days
0.4
TCGA-XR-A8TG-01A
0 years, male, white, stage:Stage I, alive, 898 days
0.4
TCGA-O8-A75V-01A
0 years, male, stage:Stage I, alive, 538 days
0.4
TCGA-ZP-A9CV-01A
0 years, male, white, stage:'--, dead, 1088 days
0.4
TCGA-DD-A116-01A
0 years, male, asian, stage:Stage IIIA, dead, 1622 days
0.4
TCGA-CC-A9FS-01A
0 years, male, asian, stage:Stage II, alive, 211 days
0.4
TCGA-RC-A6M6-01A
0 years, male, white, stage:Stage II, alive, 9 days
0.4
TCGA-UB-A7ME-01A
0 years, male, asian, stage:Stage I, alive, 486 days
0.4
TCGA-ZP-A9CY-01A
0 years, female, white, stage:'--, alive, 782 days
0.4
TCGA-UB-AA0U-01A
0 years, male, white, stage:Stage II, alive, 327 days
0.4
TCGA-DD-A1EB-01A
0 years, female, stage:Stage I, alive, 2017 days
0.4
TCGA-RG-A7D4-01A
0 years, male, black or african american, stage:Stage II, alive, 1098 days
0.4
TCGA-DD-AADL-01A
0 years, male, asian, stage:Stage I, alive, 636 days
0.4
TCGA-DD-AAEK-01A
0 years, male, asian, stage:Stage II, alive, 1067 days
0.4
TCGA-2Y-A9GZ-01A
0 years, female, white, stage:Stage II, dead, 848 days
0.4
TCGA-DD-AAE2-01A
0 years, male, asian, stage:Stage I, alive, 638 days
0.4
TCGA-DD-A73C-01A
0 years, female, white, stage:Stage IIIA, alive, 701 days
0.4
TCGA-FV-A2QR-01A
0 years, male, white, stage:Stage I, dead, 581 days
0.4
TCGA-DD-A4NN-01A
0 years, female, white, stage:Stage I, dead, 899 days
0.4
TCGA-G3-AAV3-01A
0 years, female, white, stage:Stage II, alive, 412 days
0.3
TCGA-DD-A73G-01A
0 years, female, white, stage:Stage I, alive, 3478 days
0.3
TCGA-KR-A7K8-01A
0 years, male, stage:Stage I, alive, 906 days
0.3
TCGA-DD-AADI-01A
0 years, female, asian, stage:Stage I, alive, 1085 days
0.3
TCGA-G3-A25V-01A
0 years, male, white, stage:Stage I, alive, 860 days
0.3
TCGA-DD-AAVS-01A
0 years, male, asian, stage:Stage I, alive, 1823 days
0.3
TCGA-G3-A7M8-01A
0 years, male, asian, stage:Stage I, alive, 430 days
0.3
TCGA-CC-A9FW-01A
0 years, male, asian, stage:Stage IIIA, alive, 248 days
0.3
TCGA-2Y-A9GV-01A
0 years, female, white, stage:Stage I, dead, 2532 days
0.3
TCGA-2Y-A9GT-01A
0 years, male, white, stage:Stage I, dead, 1624 days
0.3
TCGA-DD-AACU-01A
0 years, male, asian, stage:Stage I, alive, 1567 days
0.3
TCGA-CC-A7IF-01A
0 years, male, asian, stage:Stage IIIA, dead, 649 days
0.3
TCGA-ZS-A9CD-01A
0 years, male, white, stage:Stage II, dead, 1386 days
0.3
TCGA-DD-AACZ-01A
0 years, female, asian, stage:Stage I, dead, 171 days
0.3
TCGA-NI-A8LF-01A
0 years, male, white, stage:Stage I, alive, 799 days
0.3
TCGA-QA-A7B7-01A
0 years, male, black or african american, stage:Stage II, alive, 94 days
0.3
TCGA-FV-A3I1-01A
0 years, female, white, stage:Stage II, dead, 247 days
0.3
TCGA-BD-A3ER-01A
0 years, male, white, stage:Stage II, alive, 1115 days
0.3
TCGA-WX-AA46-01A
0 years, male, white, stage:Stage II, alive, 756 days
0.3
TCGA-DD-A4NI-01A
0 years, male, white, stage:Stage II, alive, 816 days
0.3
TCGA-DD-AAW2-01A
0 years, male, asian, stage:Stage I, alive, 1855 days
0.3
TCGA-G3-A7M7-01A
0 years, male, white, stage:Stage I, alive, 361 days
0.3
TCGA-DD-AAE3-01A
0 years, male, asian, stage:Stage I, alive, 566 days
0.3
TCGA-ED-A459-01A
0 years, male, asian, stage:Stage II, alive, 910 days
0.3
TCGA-2Y-A9H3-01A
0 years, male, white, stage:Stage II, alive, 1516 days
0.3
TCGA-LG-A9QC-01A
0 years, male, white, stage:Stage I, alive, 425 days
0.3
TCGA-2Y-A9HB-01A
0 years, male, stage:Stage I, alive, 260 days
0.3
TCGA-DD-A73F-01A
0 years, female, white, stage:Stage I, alive, 1085 days
0.3
TCGA-EP-A12J-01A
0 years, male, black or african american, stage:Stage I, alive, 570 days
0.3
TCGA-DD-AAVR-01A
0 years, male, asian, stage:Stage I, alive, 2513 days
0.3
TCGA-CC-A5UD-01A
0 years, male, asian, stage:Stage IIIA, dead, 304 days
0.3
TCGA-DD-AACD-01A
0 years, male, asian, stage:Stage I, dead, 381 days
0.2
TCGA-DD-AACS-01A
0 years, male, asian, stage:Stage I, alive, 1804 days
0.2
TCGA-DD-AADB-01A
0 years, male, asian, stage:Stage I, alive, 1242 days
0.2
TCGA-CC-A7IH-01A
0 years, male, asian, stage:Stage IIIA, alive, 365 days
0.2
TCGA-XR-A8TE-01A
0 years, male, white, stage:Stage IIIA, alive, 925 days
0.2
TCGA-DD-AACK-01A
0 years, male, asian, stage:Stage I, alive, 9 days
0.2
TCGA-G3-A5SM-01A
0 years, male, white, stage:Stage II, alive, 520 days
0.2
TCGA-BC-A10Y-01A
0 years, male, white, stage:'--, dead, 711 days
0.2
TCGA-G3-AAV1-01A
0 years, male, asian, stage:Stage IIIC, dead, 359 days
0.2
TCGA-DD-AAEH-01A
0 years, male, asian, stage:Stage I, alive, 784 days
0.2
TCGA-ED-A8O5-01A
0 years, female, asian, stage:Stage IIIA, alive, 406 days
0.2
TCGA-DD-AAC9-01A
0 years, male, asian, stage:Stage I, alive, 347 days
0.2
TCGA-DD-A73B-01A
0 years, female, white, stage:Stage I, dead, 283 days
0.2
TCGA-DD-AACC-01A
0 years, male, asian, stage:Stage I, dead, 1685 days
0.2
TCGA-DD-A3A1-01A
0 years, male, stage:Stage IIIA, dead, 233 days
0.2
TCGA-DD-AACG-01A
0 years, male, asian, stage:Stage II, dead, 469 days
0.2
TCGA-MI-A75H-01A
0 years, male, white, stage:'--, alive, 747 days
0.2
TCGA-DD-A4NO-01A
0 years, male, white, stage:Stage I, alive, 2245 days
0.2
TCGA-G3-AAV6-01A
0 years, female, white, stage:Stage IIIA, dead, 65 days
0.2
TCGA-2Y-A9GY-01A
0 years, female, white, stage:Stage II, dead, 757 days
0.2
TCGA-EP-A3RK-01A
0 years, male, white, stage:Stage IIIA, alive, 363 days
0.2
TCGA-ZS-A9CG-01A
0 years, male, white, stage:Stage II, alive, 341 days
0.2
TCGA-UB-A7MB-01A
0 years, male, white, stage:Stage II, alive, 601 days
0.2
TCGA-FV-A23B-01A
0 years, female, white, stage:Stage II, dead, 1852 days
0.2
TCGA-DD-AAD8-01A
0 years, female, asian, stage:Stage I, alive, 1219 days
0.2
TCGA-DD-A3A8-01A
0 years, male, white, stage:Stage II, dead, 11 days
0.2
TCGA-DD-AADY-01A
0 years, female, asian, stage:Stage I, alive, 555 days
0.2
TCGA-CC-A8HS-01A
0 years, male, asian, stage:Stage IIIC, dead, 300 days
0.2
TCGA-DD-AAVY-01A
0 years, male, asian, stage:Stage IIIA, alive, 1970 days
0.2
TCGA-ZS-A9CF-01A
0 years, male, white, stage:Stage II, alive, 2412 days
0.2
TCGA-G3-AAV5-01A
0 years, male, white, stage:Stage II, alive, 354 days
0.2
TCGA-FV-A496-01A
0 years, female, white, stage:Stage I, alive, 10 days
0.2
TCGA-DD-AAE7-01A
0 years, male, asian, stage:Stage I, alive, 644 days
0.2
TCGA-DD-A3A9-01A
0 years, female, white, stage:Stage IVB, dead, 931 days
0.2
TCGA-CC-A5UE-01A
0 years, male, asian, stage:Stage IIIB, dead, 272 days
0.2
TCGA-DD-A1EE-01A
0 years, male, white, stage:Stage IIIA, dead, 349 days
0.2
TCGA-DD-AACP-01A
0 years, male, asian, stage:Stage I, alive, 415 days
0.2
TCGA-FV-A4ZQ-01A
0 years, male, white, stage:Stage I, alive, 12 days
0.2
TCGA-3K-AAZ8-01A
0 years, male, black or african american, stage:Stage IIIB, alive, 396 days
0.2
TCGA-G3-A5SL-01A
0 years, male, white, stage:Stage II, alive, 621 days
0.2
TCGA-KR-A7K0-01A
0 years, male, white, stage:Stage I, dead, 65 days
0.2
TCGA-ED-A7PY-01A
0 years, female, asian, stage:Stage II, alive, 390 days
0.2
TCGA-MI-A75I-01A
0 years, male, black or african american, stage:'--, alive, 630 days
0.2
TCGA-G3-A5SK-01A
0 years, male, white, stage:Stage I, alive, 744 days
0.2
TCGA-UB-A7MF-01A
0 years, male, white, stage:Stage IIIA, dead, 214 days
0.2
TCGA-BC-A3KG-01A
0 years, female, white, stage:Stage II, alive, 680 days
0.2
TCGA-DD-A4NF-01A
0 years, male, white, stage:Stage I, alive, 942 days
0.1
TCGA-DD-AADA-01A
0 years, female, asian, stage:Stage I, alive, 1233 days
0.1
TCGA-2Y-A9H8-01A
0 years, female, white, stage:'--, dead, 633 days
0.1
TCGA-BC-A10Z-01A
0 years, female, white, stage:Stage I, dead, 34 days
0.1
TCGA-FV-A2QQ-01A
0 years, male, white, stage:Stage I, alive, 729 days
0.1
TCGA-G3-AAV2-01A
0 years, male, white, stage:Stage I, alive, 372 days
0.1
TCGA-DD-A4NG-01A
0 years, male, white, stage:Stage IIIA, dead, 802 days
0.1
TCGA-DD-AADQ-01A
0 years, male, asian, stage:Stage II, alive, 436 days
0.1
TCGA-DD-A73E-01A
0 years, male, white, stage:Stage I, alive, 44 days
0.1
TCGA-FV-A3R2-01A
0 years, male, white, stage:Stage I, dead, 194 days
0.1
TCGA-WQ-A9G7-01A
0 years, female, white, stage:'--, alive, 30 days
0.1
TCGA-NI-A4U2-01A
0 years, male, white, stage:Stage IIIA, dead, 1791 days
0.1
TCGA-EP-A26S-01A
0 years, male, white, stage:Stage I, alive, 608 days
0.1
TCGA-BC-A5W4-01A
0 years, male, white, stage:Stage IIIA, dead, 547 days
0.1
TCGA-DD-AADJ-01A
0 years, female, asian, stage:Stage I, alive, 1066 days
0.1
TCGA-MI-A75C-01A
0 years, male, white, stage:Stage I, alive, 291 days
0.1
TCGA-BD-A2L6-01A
0 years, male, white, stage:'--, alive, 1363 days
0.1
TCGA-DD-AACA-01A
0 years, male, asian, stage:Stage I, alive, 2301 days
0.1
TCGA-DD-AAEI-01A
0 years, male, asian, stage:Stage I, alive, 1531 days
0.1
TCGA-DD-A39W-01A
0 years, female, white, stage:Stage III, dead, 827 days
0.1
TCGA-DD-A3A5-01A
0 years, female, white, stage:Stage III, dead, 3125 days
0.1
TCGA-EP-A2KC-01A
0 years, male, black or african american, stage:Stage I, dead, 19 days
0.1
TCGA-G3-A3CJ-01A
0 years, male, american indian or alaska native, stage:Stage II, alive, 594 days
0.1
TCGA-KR-A7K2-01A
0 years, male, white, stage:Stage I, alive, 829 days
0.1
TCGA-2Y-A9H7-01A
0 years, female, white, stage:Stage I, alive, 1168 days
0.1
TCGA-RC-A7SK-01A
0 years, male, asian, stage:Stage I, alive, 472 days
0.1
TCGA-2Y-A9H4-01A
0 years, male, black or african american, stage:Stage I, alive, 1452 days
0.1
TCGA-DD-AACE-01A
0 years, male, asian, stage:Stage I, alive, 2184 days
0.1
TCGA-RC-A7SF-01A
0 years, male, asian, stage:Stage I, alive, 579 days
0.1
TCGA-DD-AACX-01A
0 years, male, asian, stage:Stage II, alive, 170 days
0.1
TCGA-CC-A8HU-01A
0 years, female, asian, stage:Stage IIIA, dead, 344 days
0.1
TCGA-DD-A11B-01A
0 years, male, white, stage:Stage I, dead, 14 days
0.1
TCGA-G3-A6UC-01A
0 years, male, white, stage:Stage IIIB, alive, 671 days
0.1
TCGA-DD-A1EJ-01A
0 years, female, white, stage:Stage IIIC, dead, 1005 days
0.1
TCGA-G3-A25Z-01A
0 years, male, asian, stage:Stage I, alive, 655 days
0.1
TCGA-WJ-A86L-01A
0 years, female, white, stage:Stage I, alive, 345 days
0.1
TCGA-DD-AAEE-01A
0 years, male, asian, stage:Stage I, alive, 810 days
0.1
TCGA-BC-A3KF-01A
0 years, female, white, stage:Stage I, alive, 8 days
0.1
TCGA-UB-A7MC-01A
0 years, male, white, stage:Stage IIIA, alive, 500 days
0.1
TCGA-DD-AACW-01A
0 years, male, asian, stage:Stage I, alive, 1424 days
0.1
TCGA-DD-AACF-01A
0 years, male, asian, stage:Stage I, dead, 365 days
0.1
TCGA-EP-A2KB-01A
0 years, female, white, stage:Stage I, dead, 596 days
0.1
TCGA-DD-A4NK-01A
0 years, female, white, stage:Stage IIIA, dead, 1210 days
0.1
TCGA-CC-A3MB-01A
0 years, male, asian, stage:Stage IIIA, dead, 315 days
0.1
TCGA-DD-AAVX-01A
0 years, male, asian, stage:Stage II, alive, 1718 days
0.1
TCGA-G3-AAV4-01A
0 years, female, white, stage:Stage I, dead, 27 days
0.1
TCGA-DD-A119-01A
0 years, male, asian, stage:Stage IV, dead, 223 days
0.1
TCGA-CC-A7IK-01A
0 years, male, asian, stage:Stage IIIA, dead, 262 days
0.1
TCGA-G3-AAV0-01A
0 years, male, asian, stage:Stage I, alive, 476 days
0.1
TCGA-ZP-A9D4-01A
0 years, female, white, stage:'--, alive, 395 days
0.1
TCGA-G3-A25U-01A
0 years, female, asian, stage:Stage I, alive, 1636 days
0.1
TCGA-DD-AACV-01A
0 years, male, asian, stage:Stage I, alive, 1531 days
0.1
TCGA-K7-A6G5-01A
0 years, male, white, stage:Stage I, alive, 512 days
0.1
TCGA-DD-A3A2-01A
0 years, female, white, stage:Stage I, dead, 2131 days
0.1
TCGA-BC-A69I-01A
0 years, male, white, stage:Stage I, alive, 387 days
0.1
TCGA-DD-A4NP-01A
0 years, male, white, stage:Stage I, alive, 3308 days
0.1
TCGA-5R-AA1C-01A
0 years, male, white, stage:Stage II, alive, 520 days
0.1
TCGA-DD-AADR-01A
0 years, male, asian, stage:Stage I, alive, 2028 days
0.1
TCGA-DD-AACQ-01A
0 years, male, asian, stage:Stage II, dead, 432 days
0.1
TCGA-G3-A3CK-01A
0 years, male, asian, stage:Stage I, alive, 585 days
0.1
TCGA-EP-A2KA-01A
0 years, female, white, stage:Stage IIIA, dead, 627 days
0.1
TCGA-DD-A3A3-01A
0 years, male, asian, stage:Stage I, dead, 535 days
0.1
TCGA-DD-AAW3-01A
0 years, male, asian, stage:Stage I, alive, 1633 days
0.1
TCGA-G3-AAUZ-01A
0 years, male, stage:Stage I, alive, 480 days
0.1
TCGA-MI-A75G-01A
0 years, male, white, stage:Stage II, alive, 698 days
0.1
TCGA-DD-A73A-01A
0 years, male, white, stage:Stage I, alive, 728 days
0.1
TCGA-DD-AADG-01A
0 years, male, asian, stage:Stage IIIA, alive, 1145 days
0.1
TCGA-DD-AAD0-01A
0 years, female, asian, stage:Stage I, alive, 137 days
0.1
TCGA-DD-AACO-01A
0 years, male, asian, stage:Stage I, alive, 1876 days
0.1
TCGA-CC-A7IG-01A
0 years, male, asian, stage:Stage II, dead, 299 days
0.1
TCGA-DD-A3A4-01A
0 years, male, white, stage:Stage IIIA, dead, 612 days
0.1
TCGA-DD-AAEA-01A
0 years, male, asian, stage:Stage I, alive, 575 days
0.1
TCGA-DD-AADU-01A
0 years, male, asian, stage:Stage II, alive, 554 days
0.1
TCGA-DD-AAE4-01A
0 years, female, asian, stage:Stage I, alive, 608 days
0.0
TCGA-DD-AAW1-01A
0 years, male, asian, stage:Stage IIIA, alive, 1989 days
0.0
TCGA-DD-AACI-01A
0 years, male, asian, stage:Stage II, alive, 1618 days
0.0
TCGA-DD-AAE1-01A
0 years, male, asian, stage:Stage I, alive, 552 days
0.0
TCGA-XR-A8TF-01A
0 years, male, white, stage:Stage I, dead, 693 days
0.0
TCGA-G3-A25S-01A
0 years, male, white, stage:Stage I, dead, 416 days
0.0
TCGA-DD-AADM-01A
0 years, male, asian, stage:Stage II, dead, 12 days
0.0
TCGA-DD-A3A7-01A
0 years, male, stage:Stage IIIB, dead, 419 days
0.0
TCGA-DD-AAEB-01A
0 years, male, asian, stage:Stage I, alive, 478 days
0.0
TCGA-DD-AAVP-01A
0 years, male, asian, stage:Stage I, alive, 2752 days
0.0
TCGA-DD-AAED-01A
0 years, male, asian, stage:Stage I, alive, 763 days
0.0
TCGA-CC-A7IL-01A
0 years, male, asian, stage:Stage IIIA, dead, 278 days
0.0
TCGA-DD-A1EL-01A
0 years, male, black or african american, stage:Stage II, dead, 415 days
0.0
TCGA-DD-AACJ-01A
0 years, male, asian, stage:Stage II, alive, 2102 days
0.0
TCGA-ZS-A9CE-01A
0 years, female, white, stage:Stage II, alive, 1241 days
0.0
TCGA-DD-A39Z-01A
0 years, female, stage:Stage II, dead, 601 days
0.0
TCGA-RC-A6M4-01A
0 years, female, white, stage:Stage IIIA, alive, 22 days
0.0
TCGA-DD-AADS-01A
0 years, male, asian, stage:Stage I, alive, 474 days
0.0
TCGA-DD-A73D-01A
0 years, female, white, stage:Stage II, alive, 693 days
0.0
TCGA-DD-A39V-01A
0 years, male, white, stage:Stage II, dead, 643 days
0.0
TCGA-2Y-A9H1-01A
0 years, male, white, stage:Stage I, dead, 1229 days
0.0
TCGA-CC-A123-01A
0 years, female, asian, stage:Stage IIIA, alive, 219 days
0.0
TCGA-DD-AAD6-01A
0 years, male, asian, stage:Stage IIIA, alive, 672 days
0.0
TCGA-DD-AAE9-01A
0 years, male, asian, stage:Stage I, alive, 722 days
0.0
TCGA-G3-A7M5-01A
0 years, male, asian, stage:Stage I, alive, 447 days
0.0
TCGA-DD-AADF-01A
0 years, female, asian, stage:Stage I, dead, 115 days
0.0
TCGA-FV-A4ZP-01A
0 years, male, white, stage:Stage IIIA, dead, 2486 days
0.0
TCGA-RC-A7S9-01A
0 years, female, asian, stage:Stage I, alive, 640 days
0.0
TCGA-DD-AAVU-01A
0 years, male, asian, stage:Stage II, alive, 2202 days
0.0
TCGA-ES-A2HS-01A
0 years, male, white, stage:Stage I, dead, 688 days
0.0
TCGA-DD-AADO-01A
0 years, male, asian, stage:Stage I, alive, 453 days
0.0
TCGA-DD-AADN-01A
0 years, male, asian, stage:Stage I, alive, 898 days
0.0
TCGA-DD-AAE6-01A
0 years, female, asian, stage:Stage I, alive, 141 days
The Survival Scatter plot shows the clinical status (i.e. dead or alive) for all individuals in the patient cohort, based on the same data that underlies the corresponding Kaplan-Meier plots. Patients that are alive at last time for follow-up are shown in blue and patients who have died during the study are shown in red.
The x-axis shows the expression levels (FPKM) of the investigated gene in the tumor tissue at the time of diagnosis. The y-axis shows the follow-up time after diagnosis (years). Both axes are complimented with kernel density curves demonstrating the data density over the axes. The top density plot shows the expression levels (FPKM) distribution among dead (red) and alive patients (blue). The right density plot shows the data density of the survived years of dead patients with high and low expression levels respectively, stratified using the cutoff indicated by the vertical dashed line through the Survival Scatter plot. This cutoff is automatically defined based on the FPKM cutoff that minimizes the p-score. The cutoff can be changed by dragging the vertical line or by entering a cutoff value in the square labeled "Current cut-off".
Under the Survival Scatter plot the p-score landscape (black curve; left axis) is shown together with dead median separation (red curve; right axis). Dead median separation is the difference in median mRNA expression between patients who have died with high and low expression, respectively. It is calculated as follows: median FPKM expression of dead patients with high expression - median FPKM expression of dead patients with low expression. This is intended to aid the user in visually exploring custom cutoffs and the associated p-scores and dead median separation.
Individual patient data is displayed and can be filtered by clicking on one or more of the category buttons on the top of the page. Categories describing expression level and patient information include: high, low, alive, dead, female, male and tumor stages. The scale of the x-axis can be toggled between linear and log-scale by clicking on the "x log" button. Mouse-over function shows TCGA ID, patient information and mRNA expression (FPKM) for each patient.
& Survival analysisi
Kaplan-Meier plots summarize results from analysis of correlation between mRNA expression level and patient survival. Patients were divided based on level of expression into one of the two groups "low" (under cut off) or "high" (over cut off). X-axis shows time for survival (years) and y-axis shows the probability of survival, where 1.0 corresponds to 100 percent.
BACE2 is not prognostic in Liver Hepatocellular Carcinoma (validation)
Stage:
Survival analysis
Current cut offi
Current cut-off shows the cut-off (FPKM) currently selected. It may be changed manually. When the current cut-off is changed, the vertical dashed line indicating cut-off, the interactive survival scatter plot and the Kaplan-Meier curve will be automatically adjusted to show results accordingly.
:
Best expression cut offi
Based on the FPKM value of each gene, patients were classified into two groups and association between prognosis (survival) and gene expression (FPKM) was examined. The best expression cut-off refers the FPKM value that yields maximal difference with regard to survival between the two groups at the lowest log-rank P-value. Best expression cut-off was selected based on survival analysis .
When clicking on this number, the vertical dashed line indicating cut-off, the interactive survival plot, and the Kaplan-Meier curve will be adjusted to show results based on the best expression cut-off.
Median expression refers to the median FPKM value calculated based on the gene expression (FPKM) data from all patients in this dataset. When clicking on this number, the vertical dashed line indicating cut-off, the interactive survival plot, and the Kaplan-Meier curve will be adjusted to show results based on the median expression.
Median follow up time refers to the median time (years) after diagnosis with this type of cancer, based on clinical data from all patients in this dataset.
: 2.14
P scorei
Log-rank P value for Kaplan-Meier plot showing results from analysis of correlation between mRNA expression level and patient survival.
0.038
5-year survival highi
5-year survival for patients with higher expression than the expression cutoff.
For melanoma and glioma, 3-year survival is shown.
57%
5-year survival lowi
5-year survival for patients with lower expression than the expression cutoff.
For melanoma and glioma, 3-year survival is shown.
67%
TCGA RNA samplesi
RNA-seq data is reported as average FPKM (number Fragments Per Kilobase of exon per Million reads), generated by the The Cancer Genome Atlas (TCGA) .
Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. FPKM values of the individual samples are presented next to the box plot.
Average TPM
9.4
Number of samples
231
Samples
Sample
Description
TPM
DO45307
0 years, female, NA, stage:4, dead, 240 days
123.3
DO45275
0 years, male, NA, stage:3, dead, 10 days
118.9
DO50829
0 years, male, NA, stage:3, alive, 570 days
110.5
DO48732
0 years, male, NA, stage:3, alive, 630 days
110.0
DO45245
0 years, female, NA, stage:2, dead, 240 days
99.9
DO45249
0 years, male, NA, stage:1, alive, 630 days
97.5
DO45299
0 years, female, NA, stage:1, alive, 1440 days
89.9
DO45297
0 years, female, NA, stage:4, dead, 1260 days
82.9
DO45289
0 years, female, NA, stage:3, alive, 360 days
71.1
DO45263
0 years, male, NA, stage:3, dead, 270 days
61.4
DO45283
0 years, male, NA, stage:3, alive, 510 days
57.8
DO45279
0 years, male, NA, stage:3, alive, 1290 days
57.1
DO48682
0 years, female, NA, stage:3, dead, 120 days
51.8
DO45205
0 years, female, NA, stage:2, dead, 90 days
49.5
DO45301
0 years, male, NA, stage:2, dead, 1440 days
43.3
DO45139
0 years, male, NA, stage:3, alive, 1320 days
40.1
DO48747
0 years, male, NA, stage:3, alive, 540 days
37.7
DO45231
0 years, male, NA, stage:2, alive, 930 days
35.1
DO45119
0 years, male, NA, stage:3, dead, 510 days
34.7
DO45303
0 years, female, NA, stage:3, alive, 990 days
27.6
DO45277
0 years, male, NA, stage:3, alive, 600 days
26.5
DO45095
0 years, male, NA, stage:2, alive, 1620 days
25.8
DO45165
0 years, male, NA, stage:2, alive, 690 days
25.2
DO45305
0 years, male, NA, stage:4, alive, 300 days
23.3
DO45159
0 years, male, NA, stage:3, alive, 1470 days
23.1
DO45157
0 years, male, NA, stage:2, alive, 1980 days
21.3
DO23526
0 years, male, NA, stage:3, alive, 1050 days
20.3
DO45251
0 years, female, NA, stage:2, alive, 900 days
19.8
DO45135
0 years, male, NA, stage:1, alive, 1410 days
19.2
DO45269
0 years, male, NA, stage:3, alive, 750 days
18.3
DO23530
0 years, male, NA, stage:4, dead, 180 days
17.0
DO45211
0 years, male, NA, stage:3, alive, 240 days
15.9
DO45221
0 years, female, NA, stage:4, dead, 390 days
15.8
DO50778
0 years, male, NA, stage:4, alive, 630 days
14.4
DO50845
0 years, male, NA, stage:3, alive, 210 days
13.0
DO45287
0 years, male, NA, stage:1, alive, 390 days
12.9
DO45113
0 years, male, NA, stage:3, alive, 1560 days
12.6
DO45273
0 years, male, NA, stage:2, alive, 480 days
12.2
DO50800
0 years, male, NA, stage:2, alive, 510 days
11.6
DO45261
0 years, male, NA, stage:3, alive, 990 days
10.9
DO48697
0 years, female, NA, stage:2, dead, 810 days
10.7
DO45121
0 years, male, NA, stage:3, alive, 1530 days
8.7
DO45241
0 years, male, NA, stage:1, alive, 1080 days
8.5
DO45103
0 years, male, NA, stage:3, alive, 450 days
8.3
DO23523
0 years, male, NA, stage:3, alive, 1080 days
8.1
DO48723
0 years, male, NA, stage:1, alive, 600 days
7.6
DO50798
0 years, male, NA, stage:3, dead, 30 days
7.5
DO50808
0 years, male, NA, stage:2, alive, 570 days
7.4
DO48720
0 years, female, NA, stage:2, alive, 570 days
7.2
DO23516
0 years, male, NA, stage:3, dead, 20 days
7.1
DO45195
0 years, male, NA, stage:1, alive, 390 days
7.0
DO45155
0 years, male, NA, stage:2, alive, 2160 days
6.7
DO45285
0 years, male, NA, stage:3, alive, 480 days
6.6
DO45143
0 years, male, NA, stage:3, alive, 1290 days
6.4
DO23535
0 years, male, NA, stage:1, alive, 960 days
6.3
DO23519
0 years, male, NA, stage:3, alive, 630 days
6.2
DO48743
0 years, female, NA, stage:2, alive, 570 days
6.1
DO50774
0 years, female, NA, stage:2, alive, 720 days
5.9
DO45233
0 years, male, NA, stage:3, alive, 900 days
5.7
DO45253
0 years, male, NA, stage:2, alive, 870 days
5.6
DO23524
0 years, female, NA, stage:2, alive, 1050 days
5.2
DO50776
0 years, male, NA, stage:1, alive, 690 days
5.0
DO50857
0 years, male, NA, stage:2, alive, 210 days
4.9
DO50855
0 years, male, NA, stage:2, alive, 570 days
4.8
DO45185
0 years, male, NA, stage:2, alive, 600 days
4.7
DO48717
0 years, male, NA, stage:4, dead, 180 days
4.6
DO48712
0 years, male, NA, stage:2, alive, 810 days
4.6
DO48700
0 years, female, NA, stage:2, alive, 810 days
4.6
DO23525
0 years, male, NA, stage:4, alive, 1050 days
4.4
DO23511
0 years, female, NA, stage:3, dead, 180 days
4.4
DO45177
0 years, female, NA, stage:3, alive, 1260 days
4.3
DO45123
0 years, female, NA, stage:2, dead, 570 days
4.2
DO50811
0 years, male, NA, stage:1, alive, 450 days
4.2
DO23547
0 years, male, NA, stage:1, alive, 1020 days
4.2
DO23515
0 years, male, NA, stage:2, alive, 1230 days
4.0
DO45181
0 years, female, NA, stage:2, alive, 1200 days
4.0
DO48737
0 years, male, NA, stage:1, alive, 720 days
3.8
DO50809
0 years, male, NA, stage:3, dead, 720 days
3.8
DO45281
0 years, male, NA, stage:4, alive, 750 days
3.8
DO45153
0 years, female, NA, stage:2, alive, 1380 days
3.7
DO50825
0 years, male, NA, stage:2, alive, 390 days
3.7
DO23546
0 years, male, NA, stage:2, alive, 1050 days
3.7
DO45229
0 years, male, NA, stage:1, alive, 990 days
3.6
DO48728
0 years, female, NA, stage:2, alive, 150 days
3.6
DO45207
0 years, male, NA, stage:1, alive, 1050 days
3.4
DO50819
0 years, female, NA, stage:2, alive, 510 days
3.3
DO45201
0 years, male, NA, stage:1, alive, 900 days
3.3
DO23551
0 years, male, NA, stage:3, dead, 150 days
3.3
DO45189
0 years, female, NA, stage:2, alive, 1200 days
3.3
DO45161
0 years, male, NA, stage:2, dead, 540 days
3.2
DO50805
0 years, male, NA, stage:2, alive, 690 days
3.2
DO45141
0 years, male, NA, stage:2, alive, 1320 days
3.1
DO48736
0 years, female, NA, stage:1, alive, 600 days
3.1
DO48693
0 years, male, NA, stage:2, alive, 900 days
3.1
DO45223
0 years, male, NA, stage:4, alive, 1020 days
3.0
DO48679
0 years, male, NA, stage:2, alive, 1200 days
2.6
DO48733
0 years, male, NA, stage:2, alive, 600 days
2.6
DO50844
0 years, male, NA, stage:4, alive, 300 days
2.6
DO50803
0 years, female, NA, stage:1, alive, 540 days
2.5
DO23531
0 years, female, NA, stage:3, alive, 900 days
2.5
DO23510
0 years, female, NA, stage:2, alive, 870 days
2.4
DO45225
0 years, male, NA, stage:1, alive, 1050 days
2.3
DO50787
0 years, male, NA, stage:3, alive, 480 days
2.3
DO45109
0 years, male, NA, stage:2, alive, 1590 days
2.3
DO23537
0 years, male, NA, stage:2, dead, 900 days
2.2
DO45213
0 years, male, NA, stage:1, alive, 1200 days
2.2
DO23508
0 years, female, NA, stage:2, alive, 390 days
2.2
DO45092
0 years, male, NA, stage:4, dead, 1200 days
2.2
DO45243
0 years, female, NA, stage:3, alive, 930 days
2.1
DO48701
0 years, male, NA, stage:2, alive, 780 days
2.0
DO50813
0 years, male, NA, stage:2, alive, 420 days
1.9
DO48760
0 years, female, NA, stage:2, alive, 690 days
1.9
DO45203
0 years, female, NA, stage:2, alive, 1170 days
1.7
DO45217
0 years, female, NA, stage:3, dead, 270 days
1.7
DO48725
0 years, male, NA, stage:1, alive, 780 days
1.7
DO45137
0 years, male, NA, stage:1, alive, 1320 days
1.6
DO48672
0 years, male, NA, stage:2, alive, 450 days
1.6
DO45149
0 years, female, NA, stage:2, alive, 1260 days
1.6
DO48761
0 years, male, NA, stage:2, alive, 870 days
1.6
DO48759
0 years, male, NA, stage:3, alive, 720 days
1.6
DO227801
0 years, female, NA, stage:1, alive, 660 days
1.6
DO50807
0 years, male, NA, stage:1, alive, 540 days
1.6
DO50815
0 years, male, NA, stage:3, alive, 150 days
1.6
DO50850
0 years, male, NA, stage:3, alive, 720 days
1.5
DO45219
0 years, male, NA, stage:2, alive, 1080 days
1.5
DO23514
0 years, male, NA, stage:2, alive, 1290 days
1.5
DO45257
0 years, male, NA, stage:3, alive, 810 days
1.5
DO23550
0 years, male, NA, stage:1, alive, 990 days
1.5
DO48719
0 years, male, NA, stage:2, alive, 690 days
1.5
DO23527
0 years, male, NA, stage:1, alive, 1050 days
1.4
DO48742
0 years, male, NA, stage:2, alive, 600 days
1.4
DO45197
0 years, male, NA, stage:2, alive, 1170 days
1.4
DO48704
0 years, female, NA, stage:3, alive, 750 days
1.3
DO48730
0 years, female, NA, stage:2, alive, 630 days
1.2
DO45259
0 years, male, NA, stage:3, alive, 330 days
1.2
DO45183
0 years, female, NA, stage:2, dead, 570 days
1.2
DO50791
0 years, female, NA, stage:1, dead, 480 days
1.2
DO45215
0 years, male, NA, stage:2, alive, 1170 days
1.2
DO45127
0 years, male, NA, stage:3, dead, 420 days
1.2
DO48716
0 years, male, NA, stage:2, alive, 720 days
1.2
DO50814
0 years, male, NA, stage:3, alive, 420 days
1.1
DO23518
0 years, male, NA, stage:2, alive, 1320 days
1.1
DO45237
0 years, male, NA, stage:2, alive, 900 days
1.1
DO50799
0 years, female, NA, stage:2, alive, 540 days
1.1
DO23538
0 years, male, NA, stage:2, alive, 450 days
1.1
DO45235
0 years, female, NA, stage:1, alive, 900 days
1.1
DO50822
0 years, male, NA, stage:2, alive, 510 days
1.0
DO50806
0 years, male, NA, stage:4, alive, 540 days
1.0
DO23513
0 years, male, NA, stage:3, alive, 1200 days
1.0
DO23545
0 years, male, NA, stage:2, dead, 570 days
1.0
DO45179
0 years, female, NA, stage:2, alive, 600 days
1.0
DO45129
0 years, male, NA, stage:3, alive, 1470 days
1.0
DO45267
0 years, male, NA, stage:3, dead, 570 days
0.9
DO45247
0 years, female, NA, stage:2, alive, 210 days
0.9
DO23541
0 years, male, NA, stage:2, alive, 930 days
0.9
DO50818
0 years, male, NA, stage:2, alive, 510 days
0.9
DO50839
0 years, female, NA, stage:3, alive, 330 days
0.9
DO45173
0 years, male, NA, stage:3, alive, 1170 days
0.9
DO50820
0 years, female, NA, stage:3, alive, 510 days
0.9
DO45125
0 years, male, NA, stage:3, alive, 1680 days
0.9
DO45199
0 years, female, NA, stage:2, alive, 1350 days
0.9
DO23536
0 years, male, NA, stage:2, alive, 930 days
0.8
DO50802
0 years, male, NA, stage:2, alive, 930 days
0.8
DO45099
0 years, male, NA, stage:3, alive, 1590 days
0.8
DO48681
0 years, male, NA, stage:2, alive, 900 days
0.8
DO45187
0 years, female, NA, stage:1, alive, 1260 days
0.8
DO45191
0 years, female, NA, stage:2, alive, 1200 days
0.8
DO50816
0 years, male, NA, stage:2, alive, 390 days
0.8
DO45255
0 years, male, NA, stage:3, alive, 720 days
0.8
DO50783
0 years, male, NA, stage:3, alive, 480 days
0.8
DO23544
0 years, male, NA, stage:2, alive, 960 days
0.8
DO23517
0 years, male, NA, stage:2, alive, 1200 days
0.8
DO23540
0 years, male, NA, stage:1, alive, 750 days
0.7
DO23528
0 years, female, NA, stage:2, alive, 1020 days
0.7
DO23552
0 years, female, NA, stage:1, alive, 810 days
0.7
DO45131
0 years, male, NA, stage:4, dead, 360 days
0.7
DO45101
0 years, male, NA, stage:2, alive, 1680 days
0.7
DO50789
0 years, female, NA, stage:2, alive, 570 days
0.7
DO23542
0 years, male, NA, stage:3, alive, 960 days
0.7
DO45145
0 years, male, NA, stage:3, dead, 60 days
0.7
DO48757
0 years, female, NA, stage:3, alive, 480 days
0.7
DO23532
0 years, female, NA, stage:1, alive, 960 days
0.7
DO48715
0 years, female, NA, stage:2, dead, 690 days
0.6
DO48706
0 years, male, NA, stage:2, alive, 870 days
0.6
DO23543
0 years, male, NA, stage:2, alive, 1020 days
0.6
DO45094
0 years, male, NA, stage:3, alive, 1650 days
0.6
DO48741
0 years, male, NA, stage:3, alive, 240 days
0.6
DO23529
0 years, male, NA, stage:4, alive, 930 days
0.6
DO48674
0 years, male, NA, stage:2, alive, 1260 days
0.6
DO45265
0 years, male, NA, stage:3, alive, 1020 days
0.6
DO23548
0 years, female, NA, stage:1, alive, 840 days
0.6
DO45115
0 years, male, NA, stage:2, alive, 840 days
0.6
DO45091
0 years, male, NA, stage:2, dead, 1320 days
0.6
DO23539
0 years, male, NA, stage:1, alive, 1110 days
0.6
DO50793
0 years, male, NA, stage:4, alive, 540 days
0.5
DO45105
0 years, male, NA, stage:1, alive, 1680 days
0.5
DO45227
0 years, female, NA, stage:2, alive, 1020 days
0.5
DO227643
0 years, male, NA, stage:2, alive, 1260 days
0.5
DO50817
0 years, male, NA, stage:2, alive, 390 days
0.5
DO45167
0 years, male, NA, stage:2, dead, 1440 days
0.5
DO48746
0 years, male, NA, stage:3, alive, 570 days
0.5
DO45117
0 years, female, NA, stage:2, dead, 1110 days
0.5
DO50859
0 years, male, NA, stage:2, alive, 180 days
0.5
DO45193
0 years, female, NA, stage:4, dead, 120 days
0.5
DO50840
0 years, male, NA, stage:2, alive, 330 days
0.5
DO45097
0 years, male, NA, stage:3, alive, 1620 days
0.5
DO50804
0 years, male, NA, stage:2, alive, 720 days
0.5
DO48677
0 years, male, NA, stage:3, alive, 1140 days
0.5
DO23512
0 years, male, NA, stage:1, alive, 1260 days
0.4
DO45096
0 years, male, NA, stage:2, dead, 1290 days
0.4
DO48721
0 years, female, NA, stage:1, alive, 900 days
0.4
DO45107
0 years, female, NA, stage:2, alive, 1710 days
0.4
DO23549
0 years, male, NA, stage:3, alive, 990 days
0.4
DO45175
0 years, male, NA, stage:2, alive, 1140 days
0.4
DO45239
0 years, male, NA, stage:2, alive, 870 days
0.4
DO45171
0 years, male, NA, stage:3, alive, 600 days
0.4
DO48727
0 years, female, NA, stage:2, dead, 390 days
0.4
DO50832
0 years, male, NA, stage:3, alive, 90 days
0.4
DO45111
0 years, male, NA, stage:2, alive, 1590 days
0.4
DO45093
0 years, male, NA, stage:2, dead, 720 days
0.4
DO45209
0 years, male, NA, stage:4, alive, 1350 days
0.3
DO23521
0 years, male, NA, stage:3, alive, 1110 days
0.3
DO23509
0 years, male, NA, stage:3, dead, 780 days
0.3
DO48751
0 years, male, NA, stage:2, dead, 480 days
0.3
DO50785
0 years, male, NA, stage:4, dead, 90 days
0.3
DO45133
0 years, male, NA, stage:3, dead, 660 days
0.2
DO48695
0 years, male, NA, stage:2, alive, 720 days
0.2
DO45169
0 years, male, NA, stage:3, alive, 1350 days
0.2
DO23534
0 years, male, NA, stage:2, alive, 840 days
0.2
DO23533
0 years, male, NA, stage:2, alive, 900 days
0.2
DO45163
0 years, male, NA, stage:2, alive, 960 days
0.1
Show allShow less
LIVER HEPATOCELLULAR CARCINOMA - Protein relative expression (CPTAC)
Number of samples
330
Samples
Sample ID
Sample type
nRPX
471
Tumor
N/A
351
Tumor
N/A
472
Normal
N/A
231
Tumor
N/A
352
Normal
N/A
473
Tumor
N/A
111
Normal
N/A
232
Normal
N/A
353
Tumor
N/A
474
Normal
N/A
112
Tumor
N/A
354
Normal
N/A
113
Tumor
N/A
355
Tumor
N/A
114
Normal
N/A
356
Normal
N/A
477
Tumor
N/A
357
Tumor
N/A
478
Normal
N/A
358
Normal
N/A
911
Tumor
N/A
912
Normal
N/A
913
Tumor
N/A
914
Normal
N/A
915
Tumor
N/A
916
Normal
N/A
917
Tumor
N/A
918
Normal
N/A
481
Tumor
N/A
361
Tumor
N/A
482
Normal
N/A
362
Normal
N/A
483
Tumor
N/A
363
Tumor
N/A
484
Normal
N/A
364
Normal
N/A
123
Tumor
N/A
365
Tumor
N/A
124
Normal
N/A
366
Normal
N/A
487
Tumor
N/A
125
Tumor
N/A
367
Tumor
N/A
488
Normal
N/A
126
Normal
N/A
368
Normal
N/A
127
Tumor
N/A
128
Normal
N/A
921
Tumor
N/A
922
Normal
N/A
923
Tumor
N/A
924
Normal
N/A
925
Tumor
N/A
926
Normal
N/A
491
Tumor
N/A
492
Normal
N/A
493
Tumor
N/A
131
Tumor
N/A
494
Normal
N/A
132
Normal
N/A
375
Tumor
N/A
376
Normal
N/A
497
Tumor
N/A
135
Tumor
N/A
498
Normal
N/A
136
Normal
N/A
257
Tumor
N/A
137
Tumor
N/A
258
Normal
N/A
138
Normal
N/A
813
Tumor
N/A
814
Normal
N/A
815
Tumor
N/A
816
Normal
N/A
937
Tumor
N/A
817
Tumor
N/A
938
Normal
N/A
818
Normal
N/A
261
Tumor
N/A
141
Tumor
N/A
262
Normal
N/A
383
Tumor
N/A
142
Normal
N/A
384
Normal
N/A
385
Tumor
N/A
386
Normal
N/A
145
Tumor
N/A
387
Tumor
N/A
146
Normal
N/A
267
Tumor
N/A
388
Normal
N/A
147
Tumor
N/A
268
Normal
N/A
148
Normal
N/A
943
Tumor
N/A
823
Tumor
N/A
944
Normal
N/A
824
Normal
N/A
1022
Normal
N/A
1021
Tumor
N/A
391
Tumor
N/A
271
Tumor
N/A
392
Normal
N/A
272
Normal
N/A
393
Tumor
N/A
394
Normal
N/A
395
Tumor
N/A
396
Normal
N/A
277
Tumor
N/A
1016
Normal
N/A
278
Normal
N/A
1015
Tumor
N/A
1014
Normal
N/A
951
Tumor
N/A
1013
Tumor
N/A
952
Normal
N/A
953
Tumor
N/A
954
Normal
N/A
713
Tumor
N/A
955
Tumor
N/A
714
Normal
N/A
956
Normal
N/A
715
Tumor
N/A
957
Tumor
N/A
716
Normal
N/A
958
Normal
N/A
1032
Normal
N/A
1031
Tumor
N/A
161
Tumor
N/A
162
Normal
N/A
283
Tumor
N/A
284
Normal
N/A
285
Tumor
N/A
286
Normal
N/A
1028
Normal
N/A
1027
Tumor
N/A
1026
Normal
N/A
1025
Tumor
N/A
721
Tumor
N/A
963
Tumor
N/A
722
Normal
N/A
964
Normal
N/A
723
Tumor
N/A
965
Tumor
N/A
724
Normal
N/A
966
Normal
N/A
967
Tumor
N/A
968
Normal
N/A
727
Tumor
N/A
728
Normal
N/A
1044
Normal
N/A
1043
Tumor
N/A
1042
Normal
N/A
1041
Tumor
N/A
171
Tumor
N/A
172
Normal
N/A
297
Tumor
N/A
298
Normal
N/A
851
Tumor
N/A
852
Normal
N/A
975
Tumor
N/A
976
Normal
N/A
977
Tumor
N/A
615
Tumor
N/A
857
Tumor
N/A
978
Normal
N/A
616
Normal
N/A
737
Tumor
N/A
858
Normal
N/A
617
Tumor
N/A
738
Normal
N/A
618
Normal
N/A
185
Tumor
N/A
186
Normal
N/A
187
Tumor
N/A
188
Normal
N/A
981
Tumor
N/A
861
Tumor
N/A
982
Normal
N/A
741
Tumor
N/A
862
Normal
N/A
983
Tumor
N/A
742
Normal
N/A
863
Tumor
N/A
984
Normal
N/A
1046
Normal
N/A
743
Tumor
N/A
864
Normal
N/A
1045
Tumor
N/A
744
Normal
N/A
865
Tumor
N/A
745
Tumor
N/A
866
Normal
N/A
746
Normal
N/A
867
Tumor
N/A
868
Normal
N/A
627
Tumor
N/A
628
Normal
N/A
191
Tumor
N/A
192
Normal
N/A
195
Tumor
N/A
196
Normal
N/A
873
Tumor
N/A
874
Normal
N/A
513
Tumor
N/A
755
Tumor
N/A
514
Normal
N/A
635
Tumor
N/A
756
Normal
N/A
877
Tumor
N/A
515
Tumor
N/A
636
Normal
N/A
878
Normal
N/A
516
Normal
N/A
517
Tumor
N/A
518
Normal
N/A
881
Tumor
N/A
882
Normal
N/A
641
Tumor
N/A
883
Tumor
N/A
642
Normal
N/A
884
Normal
N/A
523
Tumor
N/A
524
Normal
N/A
525
Tumor
N/A
526
Normal
N/A
647
Tumor
N/A
527
Tumor
N/A
648
Normal
N/A
528
Normal
N/A
411
Tumor
N/A
412
Normal
N/A
533
Tumor
N/A
413
Tumor
N/A
534
Normal
N/A
414
Normal
N/A
535
Tumor
N/A
777
Tumor
N/A
415
Tumor
N/A
536
Normal
N/A
778
Normal
N/A
416
Normal
N/A
537
Tumor
N/A
538
Normal
N/A
661
Tumor
N/A
662
Normal
N/A
421
Tumor
N/A
663
Tumor
N/A
422
Normal
N/A
664
Normal
N/A
785
Tumor
N/A
423
Tumor
N/A
665
Tumor
N/A
786
Normal
N/A
424
Normal
N/A
545
Tumor
N/A
666
Normal
N/A
425
Tumor
N/A
546
Normal
N/A
426
Normal
N/A
427
Tumor
N/A
428
Normal
N/A
671
Tumor
N/A
672
Normal
N/A
431
Tumor
N/A
311
Tumor
N/A
432
Normal
N/A
553
Tumor
N/A
312
Normal
N/A
433
Tumor
N/A
554
Normal
N/A
313
Tumor
N/A
434
Normal
N/A
314
Normal
N/A
435
Tumor
N/A
436
Normal
N/A
557
Tumor
N/A
558
Normal
N/A
563
Tumor
N/A
443
Tumor
N/A
564
Normal
N/A
685
Tumor
N/A
444
Normal
N/A
686
Normal
N/A
445
Tumor
N/A
446
Normal
N/A
567
Tumor
N/A
447
Tumor
N/A
568
Normal
N/A
327
Tumor
N/A
448
Normal
N/A
328
Normal
N/A
571
Tumor
N/A
451
Tumor
N/A
572
Normal
N/A
331
Tumor
N/A
452
Normal
N/A
573
Tumor
N/A
211
Tumor
N/A
332
Normal
N/A
574
Normal
N/A
695
Tumor
N/A
212
Normal
N/A
696
Normal
N/A
213
Tumor
N/A
455
Tumor
N/A
697
Tumor
N/A
214
Normal
N/A
456
Normal
N/A
698
Normal
N/A
217
Tumor
N/A
218
Normal
N/A
461
Tumor
N/A
341
Tumor
N/A
462
Normal
N/A
221
Tumor
N/A
342
Normal
N/A
463
Tumor
N/A
222
Normal
N/A
343
Tumor
N/A
464
Normal
N/A
223
Tumor
N/A
344
Normal
N/A
465
Tumor
N/A
224
Normal
N/A
466
Normal
N/A
467
Tumor
N/A
468
Normal
N/A
227
Tumor
N/A
228
Normal
N/A
Show allShow less
LIVER CANCER - Protein expressioni
A mouse-over function shows sample information and annotation data. Click on an image to view it in a full screen mode. Samples can be filtered based on level of antibody staining by selecting one or several of the following categories: high, medium, low and not detected. The assay and annotation is described here.
Note that samples used for immunohistochemistry by the Human Protein Atlas do not correspond to samples in the TCGA dataset.
Antibody stainingi
Antibody staining in the annotated cell types in the current human tissue is reported as not detected, low, medium, or high, based on conventional immunohistochemistry profiling in selected tissues. This score is based on the combination of the staining intensity and fraction of stained cells.
Each image is clickable and will lead to virtual microscopy that enables deeper exploration of all samples and also displays staining intensity scores, fraction scores and subcellular localization as well as patient and tissue information for each sample.