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The primary data page shows the detailed antibody staining in 76 different cell types for each analyzed antibody. In addition, for each cell type, a knowledge-based annotated protein expression score based on all analyzed antibodies is displayed furthest to the right. The images and annotations can be accessed by clicking on the tissue name or score bar. More information can be found in Assays & Annotation.
The tissues and cell types can be ordered by organ, cell type or alphabetically. If ordered by organ, the tissues are presented in groups according to functional features. If ordered by cell type, the cells are presented in groups related to origin.
This score describes the level of antibody staining observed in the annotated cell types as not detected (n), low (l), medium (m) or high (h). It is based on the staining intensity and fraction of stained cells. The images and annotations can be accessed by clicking on the tissue name or score bar. More information can be found in Assays & Annotation.
Annotated protein expressioni
This score describes a knowledge-based best estimate of the protein expression in the annotated cell types as not detected (n), low (l), medium (m) or high (h). It is a result of stringent evaluation of immunohistochemical staining pattern, RNA data from internal and external sources and available protein/gene characterization data. More information can be found in Assays & Annotation.
Summarizing texts describe the staining pattern for each antibody based on staining intensity, fraction of stained cells and subcellular localization. More information can be found in Assays & Annotation.
HPA018892
Moderate cytoplasmic positivity with additional membranous staining was observed in cells of gastro-intestinal tract, lymphoid tissues and pancreas. Endothelial cells were positive. Remaining cell types were weakly stained or negative.
HPA072690
Moderate to strong cytoplasmic positivity was observed in placenta, pancreas, thyroid gland, heart and smooth muscle and a subset of endothelial and immune cells. Remaining normal tissues were mainly negative.
CAB009820
Most normal tissues displayed moderate cytoplasmic and in a few cases membranous positivity. Endothelial cells were strongly stained. Extracellular positivity was observed in most tissues. Neuronal and lymphoid tissues were weakly stained or negative.
CAB020718
Decidual cells and reaction centre cells in tonsil showed moderate cytoplasmic staining while cardiac myocytes and endothelial cells showed distinct membranous staining. Remaining normal cells displayed weak cytoplasmic positivity or were negative.
The Human Protein Atlas project is funded
