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On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.
Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.
If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.
h
m
l
n
Ganglion cells :
Not detected
Inner nuclear layer:
High
Inner plexiform layer:
Low
Limiting membrane:
Not detected
Nerve fiber layer:
Low
Outer plexiform layer:
Low
Photoreceptor cells:
High
Pigment epithelial cells:
Not detected
RNA expressioni
A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.
The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.
Scroll down to view mRNA expression data in more detail.
Consensus:
595.7
nTPM
GTEx:
595.7
nTPM
FANTOM5:
749.3
Scaled Tags Per Million
Pig:
534.2
nTPM
Mouse:
952.9
nTPM
RETINA - Extended tissue profilei
For selected proteins extended tissue profiling is performed in addition to standard tissue microarrays. The section below contains results from the extended profiling.
, antibody HPA010698
Pigment epithelial cells
Not detected
Immunohistochemical staining of human retina shows strong cytoplasmic and membranous positivity in photoreceptor cells and cells in inner nuclear layer.
100 ฮผm
Photoreceptor cells
High
Limiting membrane
Not detected
Outer plexiform layer
Low
Inner nuclear layer
High
Inner plexiform layer
Low
Ganglion cells
Not detected
Nerve fiber layer
Low
RETINA - GTEx RNA-seqi
RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.
Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi
Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.
595.7
GTEx sample id
Sample description
nTPM
Retina Average nTPM: 595.7
Samples: 105
Max nTPM: 927.6
Min nTPM: 305.8
Std nTPM: 146.2
Median nTPM:
349_1
83 years, male
927.6
375_1
74 years, female
894.5
243_1
75 years, male
866.1
319_1
81 years, male
860.2
386_1
76 years, male
850.9
172_1
72 years, female
842.3
347_1
72 years, male
830.8
425_1
59 years, female
816.9
350_1
84 years, female
795.4
177_1
74 years, male
795.1
335_1
73 years, female
794.0
229_1
69 years, female
785.2
355_1
70 years, female
783.6
389_1
86 years, female
774.6
447_1
81 years, male
770.9
379_1
60 years, male
770.0
266_1
85 years, male
768.7
376_1
75 years, female
764.6
163_1
78 years, male
759.6
352_1
62 years, male
728.9
317_1
60 years, male
720.2
246_1
77 years, male
718.2
377_1
82 years, female
708.3
321_1
62 years, female
705.8
218_1
71 years, female
704.2
237_1
82 years, male
703.1
526_1
61 years, male
698.6
307_1
66 years, female
692.7
468_1
89 years, male
690.8
394_1
75 years, female
689.4
351_1
91 years, male
676.4
354_1
81 years, female
673.9
292_1
71 years, male
664.2
452_1
88 years, female
660.7
265_1
87 years, male
656.1
286_1
68 years, female
654.4
173_1
67 years, male
653.0
353_1
82 years, female
651.7
254_1
77 years, female
651.6
311_1
78 years, male
650.5
324_1
76 years, male
645.9
291_1
76 years, male
645.6
6_1
73 years, female
639.0
318_1
68 years, male
633.2
189_1
76 years, male
627.1
406_1
79 years, male
625.7
356_1
87 years, female
624.1
396_1
62 years, male
621.0
293_1
68 years, female
620.4
405_1
91 years, male
619.9
503_1
68 years, male
613.1
41_1
94 years, female
602.9
414_1
84 years, female
598.9
348_1
84 years, male
595.2
315_1
62 years, female
593.8
99_1
64 years, male
593.6
384_1
83 years, male
587.9
404_1
82 years, female
587.2
316_1
62 years, male
579.9
415_1
77 years, female
577.5
322_1
76 years, male
567.3
115_1
83 years, male
559.8
251_1
78 years, male
549.4
109_1
81 years, female
547.8
264_1
73 years, female
546.6
313_1
79 years, female
544.7
117_1
61 years, male
534.9
499_1
55 years, female
534.9
126_1
63 years, male
531.1
320_1
89 years, female
531.0
120_1
70 years, female
525.1
480_1
63 years, male
520.8
153_1
70 years, female
516.0
517_1
88 years, male
513.4
217_1
76 years, male
504.8
506_1
65 years, male
495.1
314_1
67 years, male
486.9
137_1
83 years, male
486.1
35_1
74 years, female
478.4
18_1
88 years, male
475.4
308_1
70 years, female
470.2
9_1
66 years, female
466.7
142_1
61 years, female
466.7
518_1
75 years, female
459.6
295_1
61 years, female
457.6
145_1
84 years, male
447.3
42_1
85 years, male
445.6
288_1
66 years, female
443.4
32_1
67 years, male
440.7
4_1
88 years, female
438.9
162_1
79 years, female
420.7
17_1
71 years, male
406.4
466_1
57 years, female
406.2
119_1
70 years, female
394.3
2_1
77 years, female
389.8
43_1
64 years, female
388.5
81_1
67 years, male
383.1
490_1
67 years, female
378.0
413_1
59 years, female
359.1
139_1
64 years, female
355.5
89_1
63 years, male
346.4
495_1
57 years, female
345.4
491_1
89 years, female
334.4
501_1
88 years, male
313.1
149_1
88 years, male
305.8
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RETINA - FANTOM5 CAGEi
RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.
Max subtype Scaled Tags Per Millioni
Max subtype Scaled Tags Per Million is the value for the subtype with the largest average Scaled Tags Per Million across the subtype samples.
Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi
Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.
Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi
Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.