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The primary data page shows the detailed antibody staining in 76 different cell types for each analyzed antibody. In addition, for each cell type, a knowledge-based annotated protein expression score based on all analyzed antibodies is displayed furthest to the right. The images and annotations can be accessed by clicking on the tissue name or score bar. More information can be found in Assays & Annotation.
The tissues and cell types can be ordered by organ, cell type or alphabetically. If ordered by organ, the tissues are presented in groups according to functional features. If ordered by cell type, the cells are presented in groups related to origin.
This score describes the level of antibody staining observed in the annotated cell types as not detected (n), low (l), medium (m) or high (h). It is based on the staining intensity and fraction of stained cells. The images and annotations can be accessed by clicking on the tissue name or score bar. More information can be found in Assays & Annotation.
Annotated protein expressioni
This score describes a knowledge-based best estimate of the protein expression in the annotated cell types as not detected (n), low (l), medium (m) or high (h). It is a result of stringent evaluation of immunohistochemical staining pattern, RNA data from internal and external sources and available protein/gene characterization data. More information can be found in Assays & Annotation.
Summarizing texts describe the staining pattern for each antibody based on staining intensity, fraction of stained cells and subcellular localization. More information can be found in Assays & Annotation.
HPA001816
Plasma and extracellular matrix showed positivity. Bone marrow poietic cells, glandular cells in the gastrointestinal tract, gall bladder and islet cells in pancreas showed moderate cytoplasmic positivity. Remaining normal cells were weakly stained or negative.
HPA024007
Cells in seminiferus ducts displayed strong nuclear staining while Leydig cells and a subpopulation of cells in gastric mucosa exhibited strong cytoplasmic positivity. Cells in CNS and lymphoid tissues except spleen were negative. Remaining normal tissues demonstrated weak to moderate cytoplasmic staining. Plasma showed distinct positivity.
CAB016790
A majority of normal tissues displayed weak to moderate cytoplasmic and occasional membranous positivity. Distinct positivity was observed in plasma, alveolar macrophages and in Leydig cells. Neuronal cells of CNS and lymphoid tissues were negative.