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Widespread cytoplasmic and nuclear staining in subsets of glial cells, most abundant in olfactory bulb, cerebellum, some white matter tracts (like optic tract, middle cerebellar peduncle), choroid plexus and ventricle wall. Bergmann-glia in cerebellum exhibits strong staining. Also, some nuclei in the medulla/pons exhibit moderate neuronal cytoplasmic and nulcear stianing, like in the n ambiguus or inferior olivary nucleus.
Positive cells and structuresi
Manually selected location of the protein positivity, observed by immunofluorescence staining in mouse brain.
Glia. Choroid plexus and ventricle wall of ependymal cells.
Positivity in selected cells in principle sensory trigeminal nucleus