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Protein Classes
Main classes
Protein class
No of genes
Code
No of genes with
tissue profiles
Source
Kinases
503
Ki
273
UniProt
CD markers
367
Cd
219
UniProt
Blood group antigen proteins
29
Ba
12
UniProt
Transporters
472
Tr
162
Transport Classification Database (TCDB)
Ribosomal proteins
158
Ri
29
UniProt
Peptidases
520
Pe
182
UniProt/Merops
GPCRs excl olfactory receptors
392
Gp
119
UniProt
Transcription factors
1492
Tf
391
DBD
Enzymes
2492
Ez
980
ENZYME
SH2-domain containing proteins
109
SH
66
InterPro
SH3-domain containing proteins
217
SD
93
InterPro
Project related classes
Protein class
No of genes
Code
No of genes with
tissue profiles
Source
Candidate cancer biomarkers
1067
Cb
668
Plasma Proteome Institute
Plasma proteins
687
Pp
384
Plasma Proteome Institute
Candidate cardiovascular disease genes
166
Cc
108
Plasma Proteome Institute
Uniprot - no evidence at protein level
7575
Up
977
UniProt
Kinases
Protein class
No of genes
Code
No of genes with
tissue profiles
Source
Kinases
503
Ki
273
UniProt
AGC Ser/Thr protein kinases
57
Kg
35
UniProt
Atypical kinases
24
Ka
10
UniProt
TKL Ser/Thr protein kinases
34
Kl
21
UniProt
RGC receptor guanylate cyclase kinases
5
Kr
1
UniProt
CMGC Ser/Thr protein kinases
61
Km
36
UniProt
CAMK Ser/Thr protein kinases
72
Kc
35
UniProt
Tyr protein kinases
92
Kt
63
UniProt
STE Ser/Thr protein kinases
55
Ks
31
UniProt
NEK Ser/Thr protein kinases
11
Kn
5
UniProt
CK1 Ser/Thr protein kinases
12
Kk
6
UniProt
Transporters
Protein class
No of genes
Code
No of genes with
tissue profiles
Source
Transporters
472
Tr
162
Transport Classification Database (TCDB)
Transporter channels and pores
163
Tc
63
Transport Classification Database (TCDB)
Transport Electron Carriers
9
Tt
3
Transport Classification Database (TCDB)
Electrochemical Potential-driven transporters
133
Te
35
Transport Classification Database (TCDB)
Accessory Factors Involved in Transport
28
Ta
11
Transport Classification Database (TCDB)
Primary Active Transporters
101
Tp
44
Transport Classification Database (TCDB)
Peptidases
Protein class
No of genes
Code
No of genes with
tissue profiles
Source
Peptidases
520
Pe
182
UniProt/Merops
Aspartic-type peptidases
16
Pa
9
UniProt/Merops
Serine-type peptidases
169
Ps
58
UniProt/Merops
Cysteine-type peptidases
138
Pc
52
UniProt/Merops
Threonine-type peptidases
27
Pt
6
UniProt/Merops
Metallopeptidases
170
Pm
57
UniProt/Merops
G-protein coupled receptors
Protein class
No of genes
Code
No of genes with
tissue profiles
Source
G-protein coupled receptors
773
Gr
122
UniProt
Adenosine and adenine nucleotide receptors
17
Ga
5
UniProt
GPCRs excl olfactory receptors
392
Gp
119
UniProt
Family T2R receptors (taste receptor GPCRs)
17
Gt
0
UniProt
Serotonin receptors
12
Gs
6
UniProt
Odorant/olfactory and gustatory receptors
381
Go
3
UniProt
Chemokines and chemotactic factors receptors
31
Gh
16
UniProt
Family fz/smo receptors
11
Gf
4
UniProt
Family 2 (B) receptors
49
Gb
15
UniProt
Opsins
10
Gi
1
UniProt
Lysolipids receptors
15
Gl
4
UniProt
Enzymes
Protein class
No of genes
Code
No of genes with
tissue profiles
Source
Enzymes
2492
Ez
980
ENZYME
Oxidoreductases
347
Eo
117
ENZYME
Ligase
121
El
46
ENZYME
Lyases
99
Ey
47
ENZYME
Transferases
1082
Et
454
ENZYME
Isomerase
89
Ei
37
ENZYME
Hydrolases
794
Eh
299
ENZYME
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