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Dr Lisa Berglund
Linn Fagerberg (PhD-student), Mattias Forsberg (research engineer), Kalle Jonasson (research engineer), Per Oksvold (research engineer), Åsa Sivertsson (post-doc) and Martin Zwahlen (research engineer).
(i) To deliver custom made software solutions for all operations in the
Human Proteome Resource (HPR) program, (ii) to provide the collected
data to the public via the Human Protein Atlas, and (iii) to initiate
the HPR analysis of human proteins by in silico selection of Protein
Epitope Signature Tags (PrESTs) with subsequent design of
oligonucleotide primer pairs for the cloning procedures in the Molecular
Biology module.
With the HPR-LIMS (Laboratory Information Management System) as the
backbone, data is collected from each module in the pipeline.
The protein expression profiles and raw data from the project is
published on the Human Protein Atlas public web site through annual
releases.
The Bioinformatics group performs computer-based analysis of protein
sequences for selection of protein fragments (PrESTs) to be used as
immunogens for generation of target-specific polyclonal antibodies. The
group is also heavily involved in all research performed in the HPR
program, such as data collection, data interpretation and statistical
analysis.
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