News ArticlesMultiplex tissue image of the month - CFAP45 in endometriumThis month, cilia and flagella associated protein 45 (gene: CFAP45) is highlighted among the sparse population of ciliated cells in endometrial glands through the use of multiplex immunohistochemistry (mIHC/IF)...Read more The multilocalizing proteomeKnowing where proteins are localized in the cell can help map out cellular processes and signaling pathways to better understand the flow of information within and between cells. The subcellular location of a protein is thought to be tightly linked to its function so that a protein in the nucleus may be involved in gene regulation, while one in the mitochondria might play a role in energy production. However, after having studied the subcellular location of the majority of all human proteins it seems that more than half are in fact multilocalizing proteins (MLPs)...Read more Mathias Uhlen on Europes top one biotech podcastKTH professor Mathias Uhlén, founder of the Human Protein Atlas and co-founder of numerous biotech companies, discusses science and entrepreneurship with Philip Hemme in a Flot.bio podcast episode...Read more SMIM17 - a `Gene Doe` of the brainAmong the about 20,000 genes giving rise to the human proteome there are still many rather unknown but potentially interesting genes that deserve some extra attention. Here we will focus on SMIM17, a gene with little evidence and specific expression in the brain...Read more The circulating proteome - developments, challenges, and trendsIn an article in the Journal of Proteome Research representatives of HUPO's Human Plasma Proteome Project (HPPP), including several HPA affiliated researchers, present the current progress in the study and mapping of the circulating proteome and discuss how updates of proteomics methods, emerging technologies, and investigations of proteoforms and protein networks can impact the understanding of the proteins circulating in blood...Read more |